Pharmacological, non-pharmacological and stem cell therapies for the management of autism spectrum disorders: A focus on human studies

2020 ◽  
Vol 152 ◽  
pp. 104579 ◽  
Author(s):  
Francesca Pistollato ◽  
Tamara Yuliett Forbes-Hernández ◽  
Ruben Calderón Iglesias ◽  
Roberto Ruiz ◽  
Maria Elexpuru Zabaleta ◽  
...  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Human Studies ◽  
Stem Cell Therapies ◽  
Cell Therapies ◽  
Spectrum Disorders

scholarly journals Efficacy of Fetal Stem Cell Transplantation in Autism Spectrum Disorders: An Open-Labeled Pilot Study

2014 ◽  
Vol 23 (1_suppl) ◽  
pp. 105-112 ◽  
Author(s):  
James Jeffrey Bradstreet ◽  
Nataliia Sych ◽  
Nicola Antonucci ◽  
Mariya Klunnik ◽  
Olena Ivankova ◽  
...  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Pilot Study ◽  
Stem Cell Transplantation ◽  
Cell Transplantation ◽  
Autism Spectrum ◽  
Fetal Stem Cell ◽  
Spectrum Disorders

Pharmacological Modulation of GABA Function in Autism Spectrum Disorders: A Systematic Review of Human Studies

2015 ◽  
Vol 46 (3) ◽  
pp. 825-839 ◽  
Author(s):  
Natascia Brondino ◽  
Laura Fusar-Poli ◽  
Cristina Panisi ◽  
Stefano Damiani ◽  
Francesco Barale ◽  
...  
Keyword(s):  
Systematic Review ◽  
Autism Spectrum Disorders ◽  
Autism Spectrum ◽  
Human Studies ◽  
Pharmacological Modulation ◽  
Spectrum Disorders ◽  
Gaba Function

Prospect of Stem Cell Therapy for Autism Spectrum Disorders

2011 ◽  
Vol 4 (3) ◽  
pp. 134
Author(s):  
Xuejun Kong ◽  
◽  
Xiaochun Wang ◽  
William Stone ◽  
◽  
...  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Autism Spectrum ◽  
Spectrum Disorders

scholarly journals The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery

2014 ◽  
Vol 3 (11) ◽  
pp. 1275-1286 ◽  
Author(s):  
David J. Brick ◽  
Hubert E. Nethercott ◽  
Samantha Montesano ◽  
Maria G. Banuelos ◽  
Alexander E. Stover ◽  
...  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Drug Discovery ◽  
Disease Modeling ◽  
Orange County ◽  
Autism Spectrum ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Spectrum Disorders

scholarly journals The Autism Spectrum Disorders Stem Cell Resource at Children's Hospital of Orange County: Implications for Disease Modeling and Drug Discovery

2015 ◽  
Vol 4 (11) ◽  
pp. 1369-1369
Author(s):  
David J. Brick ◽  
Hubert E. Nethercott ◽  
Samantha Montesano ◽  
Maria G. Banuelos ◽  
Alexander E. Stover ◽  
...  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Drug Discovery ◽  
Disease Modeling ◽  
Orange County ◽  
Autism Spectrum ◽  
Children's Hospital ◽  
Children’S Hospital ◽  
Spectrum Disorders

scholarly journals Autism Spectrum Disorders: Is Mesenchymal Stem Cell Personalized Therapy the Future?

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Dario Siniscalco ◽  
Anna Sapone ◽  
Alessandra Cirillo ◽  
Catia Giordano ◽  
Sabatino Maione ◽  
...  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Mesenchymal Stem Cell ◽  
Autism Spectrum ◽  
Molecular Medicine ◽  
Stem Cell Population ◽  
Great Promise ◽  
Mesenchymal Stem Cell Transplantation ◽  
The Future ◽  
Spectrum Disorders

Autism and autism spectrum disorders (ASDs) are heterogeneous neurodevelopmental disorders. They are enigmatic conditions that have their origins in the interaction of genes and environmental factors. ASDs are characterized by dysfunctions in social interaction and communication skills, in addition to repetitive and stereotypic verbal and nonverbal behaviours. Immune dysfunction has been confirmed with autistic children. There are no defined mechanisms of pathogenesis or curative therapy presently available. Indeed, ASDs are still untreatable. Available treatments for autism can be divided into behavioural, nutritional, and medical approaches, although no defined standard approach exists. Nowadays, stem cell therapy represents the great promise for the future of molecular medicine. Among the stem cell population, mesenchymal stem cells (MSCs) show probably best potential good results in medical research. Due to the particular immune and neural dysregulation observed in ASDs, mesenchymal stem cell transplantation could offer a unique tool to provide better resolution for this disease.

Effectiveness of Stem Cell Therapy in Autism Spectrum Disorders: Case Study of Identical Twins

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Sandhya K ◽  
◽  
Shobha HC ◽  
Keyword(s):  
Stem Cell ◽  
Autism Spectrum Disorders ◽  
Cell Therapy ◽  
Stem Cell Therapy ◽  
Present Report ◽  
Neurodevelopmental Disorder ◽  
Autism Spectrum ◽  
Immune System Dysfunction ◽  
Spectrum Disorders

Autism Spectrum Disorders (ASDs) is a neurodevelopmental disorder with immune system dysfunction. Recent year’s researches have exposed importance of cell based therapies, which were proposed and applied to ASDs as ASDs are considered to be a Neurobiological condition. Although a few studies show stem cell therapy as an active treatment, method for individuals with ASDs there is a lack of empirical evidences to confirm the effectiveness. A twin case study is presented who are diagnosed as having ASDs who had undergone Stem cell therapy treatment. The results of detailed Speech and Language evaluations and other treatments the children had undergone are the focus of present report. Precautions to be taken while choosing the right management option, which involves careful parental counselling are discussed.

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