scholarly journals Pretreatment of red palm oil extracted from palm fruit (Elaeis guineensis) attenuates carbon tetrachloride induced toxicity in Wistar rats

2021 ◽  
pp. 100079
Author(s):  
Okezie Emmanuel ◽  
Ugochukwu M. Okezie ◽  
Emeka J. Iweala ◽  
Eziuche A. Ugbogu
2013 ◽  
Vol 2013 ◽  
pp. 1-19 ◽  
Author(s):  
Olawale R. Ajuwon ◽  
Emma Katengua-Thamahane ◽  
Jacques Van Rooyen ◽  
Oluwafemi O. Oguntibeju ◽  
Jeanine L. Marnewick

The possible protective effects of an aqueous rooibos extract (Aspalathus linearis), red palm oil (RPO) (Elaeis guineensis), or their combination ontert-butyl-hydroperoxide-(t-BHP-)induced oxidative hepatotoxicity in Wistar rats were investigated.tert-butyl hydroperoxide caused a significant (P<0.05) elevation in conjugated dienes (CD) and malondialdehyde (MDA) levels, significantly (P<0.05) decreased reduced glutathione (GSH) and GSH : GSSG ratio, and induced varying changes in activities of catalase, superoxide dismutase, glutathione peroxidase, and glutathione reductase in the blood and liver. This apparent oxidative injury was associated with histopathological changes in liver architecture and elevated levels of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH). Supplementation with rooibos, RPO, or their combination significantly (P<0.05) decreased CD and MDA levels in the liver and reduced serum level of ALT, AST, and LDH. Likewise, changes observed in the activities of antioxidant enzymes and impairment in redox status in the erythrocytes and liver were reversed. The observed protective effects when rooibos and RPO were supplemented concomitantly were neither additive nor synergistic. Our results suggested that rooibos and RPO, either supplemented alone or combined, are capable of alleviatingt-BHP-induced oxidative hepatotoxicity, and the mechanism of this protection may involve inhibition of lipid peroxidation and modulation of antioxidants enzymes and glutathione status.


1994 ◽  
Vol 15 (2) ◽  
pp. 1-8 ◽  
Author(s):  
Choo Yuen May

Crude palm oil is the richest natural plant source of carotenoids in terms of retinol (provitamin A) equivalent. This article reports on » the carotenoids found in palm oil, its fractions, byproducts, and derivatives from the Elaeis guineensis and E. oleifera palms, including their hybrids and a back-cross, as well as the carotenoids of pressed palm fibres, second-pressed oil, palm leaves, and palm-derived alkyl esters; » two novel procedures for preparing highly concentrated sources of carotenoids (>80,000 ppm), by recovery by palm alkyl esters, and by retention and concentration in deacidified and deodorized red palm oil; » the carotenoid content and profiles of the above sources obtained by high-performance liquid chromatography; and » nutritional effects of palm oil carotenoids and their potential applications for health promotion and disease prevention.


2012 ◽  
Vol 26 (S1) ◽  
Author(s):  
Ademola Ayeleso ◽  
Oluwafemi Oguntibeju ◽  
Nicole Brooks

2011 ◽  
Vol 205 ◽  
pp. S191
Author(s):  
O.R. Ajuwon ◽  
O.O. Fakoya ◽  
O.V. Afuwape ◽  
B.M. Raheem ◽  
O. Oguntibeju ◽  
...  

2021 ◽  
Vol 12 (2) ◽  
pp. 1470-1479

Basically, oil palm has three types of fruit, namely the dura, pisifera, and tenera varieties. These three varieties have different characteristics, likewise with resulting Crude Palm Oil (CPO) levels. Generally, palm oil contains 500–700 ppm of carotenoid compounds, and the amount is equivalent to 15 times the carotenoids in carrots and 300 times in tomatoes. This is a study of information about the carotenoid composition of three varieties of oil palm fruit and applying the most superior analytical methods to obtain carotenoids from CPO. The purpose of this review is to examine the carotenoid composition of three varieties of oil palm fruit and carotenoid analysis methods presented for consideration as a reference. The method used in this review is the inclusion and exclusion criteria in literary search. The results showed that the carotenoid composition of the three varieties of oil palm in the presence of 11 types of carotene and the highest percentage composition was β-carotene with a content range of 54.39–56.02%. As for the development of new methods for carotenoid analysis from CPO, namely Raman and FT-NIR spectroscopy with the advantages of being environmentally friendly, not using solvents, and fast measurement compared to methods UV-Vis Spectrophotometry, UPLC, and HPLC.


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