Triterpene glycosides and phenylpropane derivatives from Staurogyne concinnula possessing anti-angiogenic activity

2021 ◽  
Vol 184 ◽  
pp. 112666
Author(s):  
Thanh-Hoa Vo ◽  
Yu-Chi Lin ◽  
Chia-Ching Liaw ◽  
Wen-Pin Pan ◽  
Jing-Jy Cheng ◽  
...  
Keyword(s):  
Triterpene Glycosides ◽  
Angiogenic Activity

Highly Potent rhenium(I) Tricarbonyl Complexes with Dual Anticancer and Anti-Angiogenic Activity Against Colorectal Carcinoma

2020 ◽  
Author(s):  
Joachim Delasoie ◽  
Aleksandar Pavic ◽  
Noémie Voutier ◽  
Sandra Vojnovic ◽  
Aurélien Crochet ◽  
...  
Keyword(s):  
Colorectal Carcinoma ◽  
Anticancer Drugs ◽  
Xenograft Model ◽  
Therapeutic Window ◽  
Low Doses ◽  
Sunitinib Malate ◽  
Angiogenic Activity ◽  
Antimetastatic Activity ◽  
Clinical Drugs

Synthesized and characterized a series of rhenium(I) trycarbonyl-based complexes with increased lipophilicity. Two of these novel compounds were discovered to possess remarkable anticancer, anti-angiogenic and antimetastatic activity <i>in vivo</i> (zebrafish-human CRC xenograft model), being effective at very low doses (1-3 µM). At doses as high as 250 µM the complexes did not provoke toxicity issues encountered in clinical anticancer drugs (cardio-, hepato-, and myelotoxicity). The two compounds exceed the antiproliferative and anti-angiogenic potency of clinical drugs cisplatin and sunitinib-malate, and display a large therapeutic window.

Crocin Rich Extract of Nyctanthes arbor-tristis Flower Calyx Induces Anti-angiogenic Activity

2015 ◽  
Vol 06 (999) ◽  
pp. 1-1
Author(s):  
Neha D.Pawar ◽  
Shital S.Panchal ◽  
Kumaravelu J. ◽  
Tasneem Shahmalak ◽  
Chhaya Gadgoli
Keyword(s):  
Angiogenic Activity

scholarly journals Vinegar-processed Curcuma phaeocaulis promotes anti-angiogenic activity and reduces toxicity in zebrafish and rat models

2021 ◽  
Vol 59 (1) ◽  
pp. 410-417
Author(s):  
Wan Liao ◽  
Yi Chen ◽  
Zongping Zhu ◽  
Jiao Chen ◽  
Tianhui Gao ◽  
...  
Keyword(s):  
Angiogenic Activity ◽  
Rat Models

Triterpene glycosides ofSalsola micranthera. II. The strucutre of salsoloside E

1984 ◽  
Vol 20 (1) ◽  
pp. 60-64
Author(s):  
Ch. Annaev ◽  
M. Isamukhamedova ◽  
N. K. Abubakirov
Keyword(s):  
Triterpene Glycosides

Two new oleanane triterpene glycosides from Gymnema inodorum

2008 ◽  
Vol 2008 (11) ◽  
pp. 655-657 ◽  
Author(s):  
Dingyong Wang ◽  
Guocheng Li ◽  
Yujing Feng ◽  
Suying Xu
Keyword(s):  
Triterpene Glycosides ◽  
Dioic Acid

Two new oleanane triterpene glycosides were isolated from the n-BuOH extract of Gymnema inodorum. On the basis of spectroscopic evidences, their structures were elucidated as 2α, 3β-dihydroxy-olean-12-ene-23, 28-dioic acid-3-O-β-D-glucopyrano-side and 2α, 3β, 15β-trihydroxy-olean-12-ene-23, 28-dioic acid-3-O-β-D-gluco-pyranoside.

Triterpene glycosides with in vitro anti-inflammatory activity from Cyclamen repandum tubers

2010 ◽  
Vol 345 (5) ◽  
pp. 709-714 ◽  
Author(s):  
Stefano Dall’Acqua ◽  
Ignazio Castagliuolo ◽  
Paola Brun ◽  
Federica Ditadi ◽  
Giorgio Palù ◽  
...  
Keyword(s):  
Triterpene Glycosides ◽  
Inflammatory Activity ◽  
Anti Inflammatory
Sign in / Sign up

Export Citation Format

Share Document