The hydroperoxyl and superoxide anion radical scavenging activity of anthocyanidins in physiological environments: Theoretical insights into mechanisms and kinetics

Six purple corn grains were chosen to investigate their antioxidant activities and the relationships between anthocyanins and phenolics contents with antioxidant activities. Purple grains were screened for their antioxidant potentials using various in-vitro models such as superoxide anion radical scavenging activity and reducing power at various concentrations. The result showed that ZS39 and FS11 exhibited the highest anthocyanins and total phenolics contents. ZS39 and FS11 also exhibited the highest superoxide anion radical scavenging activity. There was no significant difference among the reducing power of six different purple corn grain extracts. It was found that there were positive correlations between anthocyanins and superoxide anion radical scavenging activity or reducing power, R2=0.9911, R2=0.9873, respectively. Whereas the correlations between total phenolics and superoxide anion radical scavenging activity or reducing power, R2=0.9863, R2=0.9826, respectively. It suggested that purple corn appeared to be a rich and interesting source of natural antioxidants.

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The presence of thecagpathogenicity island is associated with increased superoxide anion radical scavenging activity byHelicobacter pylori

FEMS Immunology & Medical Microbiology ◽

10.1016/j.femsim.2004.10.018 ◽

2005 ◽

Vol 44 (2) ◽

pp. 227-232 ◽

Cited By ~ 9

Author(s):

Jacob J. BriedÃ© ◽

Raymond G.J. Pot ◽

Ernst J. Kuipers ◽

Arnoud H.M. Vliet ◽

Jos C.S. Kleinjans ◽

...

Keyword(s):

Superoxide Anion ◽

Anion Radical ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Superoxide Anion Radical ◽

Scavenging Activity

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Mechanisms of the hydroxyl and superoxide anion radical scavenging activity and protective effect on lipid peroxidation of thymoquinone: a DFT study

Monatshefte für Chemie - Chemical Monthly ◽

10.1007/s00706-014-1341-3 ◽

2014 ◽

Vol 146 (4) ◽

pp. 601-611 ◽

Cited By ~ 9

Author(s):

Keivan Akhtari ◽

Keyumars Hassanzadeh ◽

Bahareh Fakhraei ◽

Nahid Fakhraei ◽

Halaleh Hassanzadeh ◽

...

Keyword(s):

Lipid Peroxidation ◽

Protective Effect ◽

Superoxide Anion ◽

Anion Radical ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Superoxide Anion Radical ◽

Dft Study ◽

Scavenging Activity

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Optimization of Pyrogallol Autoxidation Conditions and Its Application in Evaluation of Superoxide Anion Radical Scavenging Capacity for Four Antioxidants

Journal of AOAC International ◽

10.5740/jaoacint.15-0223 ◽

2016 ◽

Vol 99 (2) ◽

pp. 504-511 ◽

Cited By ~ 7

Author(s):

Qing-An Zhang ◽

Xi Wang ◽

Yun Song ◽

Xue-Hui Fan ◽

Juan Francisco García Martín

Keyword(s):

Ascorbic Acid ◽

Antioxidant Capacity ◽

Gallic Acid ◽

Superoxide Anion ◽

Anion Radical ◽

Radical Scavenging Activity ◽

Radical Scavenging ◽

Superoxide Anion Radical ◽

Scavenging Activity ◽

Pyrogallol Autoxidation

Abstract In this study, some factors influencing pyrogallol autoxidation, including EDTA, temperature, and solvent, were systematically investigated to improve its feasibility in the evaluation of antioxidants for the first time. Subsequently, the improved pyrogallol autoxidation conditions were used to assess the superoxide anion scavenging activity (SASA) of four commonly used antioxidants, namely, ascorbic acid, rutin, catechin, and gallic acid, by both the reaction rate method and the terminated method. The results indicate that pyrogallol autoxidation could be successfully used to determine the antioxidant capacity of ascorbic acid and rutin, which correspondingly suggests the feasibility of its use to measure the superoxide anion radical scavenging activity of polysaccharides and flavonols, because these compounds have a similar basic structural unit as ascorbic acid and rutin, respectively. Unexpectedly, however, pyrogallol autoxidation cannot be used to evaluate the SASA of catechin and gallic acid, although their good antioxidant capacity was confirmed by the 1,1-diphenyl-2-picrylhydrazyl assay. Together, these results suggest the importance of noting the conditions used for pyrogallol autoxidation when assessing the SASA of targeted compounds.

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