Basal lamina characterization in frozen-thawed and long-term grafted human prepubertal ovarian tissue

2021 ◽  
Vol 42 (5) ◽  
pp. 859-869
Author(s):  
Charlotte Philippart ◽  
Rossella Masciangelo ◽  
Alessandra Camboni ◽  
Jacques Donnez ◽  
Marie-Madeleine Dolmans
Keyword(s):  
Basal Lamina ◽  
Ovarian Tissue

scholarly journals Impact of freezing and thawing of human ovarian tissue on follicular growth after long-term xenotransplantation

2011 ◽  
Vol 28 (12) ◽  
pp. 1157-1165 ◽  
Author(s):  
Christiani A. Amorim ◽  
Anu David ◽  
Marie-Madeleine Dolmans ◽  
Alessandra Camboni ◽  
Jacques Donnez ◽  
...  
Keyword(s):  
Ovarian Tissue ◽  
Follicular Growth ◽  
Freezing And Thawing ◽  
Human Ovarian Tissue

Slush nitrogen vitrification of human ovarian tissue does not alter gene expression and improves follicle health and progression in long-term in vitro culture

2018 ◽  
Vol 110 (7) ◽  
pp. 1356-1366 ◽  
Author(s):  
Vincenza Barbato ◽  
Roberto Gualtieri ◽  
Teresa Capriglione ◽  
Maria Michela Pallotta ◽  
Sabrina Braun ◽  
...  
Keyword(s):  
Gene Expression ◽  
In Vitro Culture ◽  
Ovarian Tissue ◽  
Human Ovarian Tissue

Successful achievement after heterotopic transplantations of long-term stored ovarian tissue in Hodgkin’s lymphoma survivor

2019 ◽  
Vol 35 (6) ◽  
pp. 470-472 ◽  
Author(s):  
R. Fabbri ◽  
R. Seracchioli ◽  
R. Vicenti ◽  
R. Paradisi ◽  
S. Rossi ◽  
...  
Keyword(s):  
Hodgkin’S Lymphoma ◽  
Ovarian Tissue ◽  
Hodgkin's Lymphoma

scholarly journals Polycystic Ovary Syndrome, Insulin Resistance, and Obesity: Navigating the Pathophysiologic Labyrinth

2014 ◽  
Vol 2014 ◽  
pp. 1-17 ◽  
Author(s):  
Joselyn Rojas ◽  
Mervin Chávez ◽  
Luis Olivar ◽  
Milagros Rojas ◽  
Jessenia Morillo ◽  
...  
Keyword(s):  
Insulin Resistance ◽  
Polycystic Ovary Syndrome ◽  
Polycystic Ovary ◽  
Ovarian Tissue ◽  
Ovary Syndrome ◽  
Main Culprit ◽  
Exact Etiology

Polycystic ovary syndrome (PCOS) is a highly prevalent endocrine-metabolic disorder that implies various severe consequences to female health, including alarming rates of infertility. Although its exact etiology remains elusive, it is known to feature several hormonal disturbances, including hyperandrogenemia, insulin resistance (IR), and hyperinsulinemia. Insulin appears to disrupt all components of the hypothalamus-hypophysis-ovary axis, and ovarian tissue insulin resistance results in impaired metabolic signaling but intact mitogenic and steroidogenic activity, favoring hyperandrogenemia, which appears to be the main culprit of the clinical picture in PCOS. In turn, androgens may lead back to IR by increasing levels of free fatty acids and modifying muscle tissue composition and functionality, perpetuating this IR-hyperinsulinemia-hyperandrogenemia cycle. Nonobese women with PCOS showcase several differential features, with unique biochemical and hormonal profiles. Nevertheless, lean and obese patients have chronic inflammation mediating the long term cardiometabolic complications and comorbidities observed in women with PCOS, including dyslipidemia, metabolic syndrome, type 2 diabetes mellitus, and cardiovascular disease. Given these severe implications, it is important to thoroughly understand the pathophysiologic interconnections underlying PCOS, in order to provide superior therapeutic strategies and warrant improved quality of life to women with this syndrome.

scholarly journals Assessment of long-term function of heterotopic transplants of vitrified ovarian tissue in cynomolgus monkeys

2012 ◽  
Vol 27 (8) ◽  
pp. 2420-2429 ◽  
Author(s):  
N. Suzuki ◽  
S. Hashimoto ◽  
S. Igarashi ◽  
S. Takae ◽  
M. Yamanaka ◽  
...  
Keyword(s):  
Ovarian Tissue ◽  
Cynomolgus Monkeys ◽  
Term Function
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