CMS121, a fatty acid synthase inhibitor, protects against excess lipid peroxidation and inflammation and alleviates cognitive loss in a transgenic mouse model of Alzheimer's disease

Synthase Inhibitor

Dietary n-3 polyunsaturated fatty acid depletion activates caspases and decreases NMDA receptors in the brain of a transgenic mouse model of Alzheimer's disease

European Journal of Neuroscience ◽

10.1111/j.1460-9568.2005.04253.x ◽

2005 ◽

Vol 22 (3) ◽

pp. 617-626 ◽

Cited By ~ 165

Author(s):

Frédéric Calon ◽

Giselle P. Lim ◽

Takashi Morihara ◽

Fusheng Yang ◽

Oliver Ubeda ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Fatty Acid ◽

Mouse Model ◽

Nmda Receptors ◽

Transgenic Mouse ◽

Polyunsaturated Fatty Acid ◽

Transgenic Mouse Model ◽

The Brain

Faculty Opinions recommendation of Preserved fronto-striatal plasticity and enhanced procedural learning in a transgenic mouse model of Alzheimer's disease overexpressing mutant hAPPswe.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1020559.235469 ◽

2004 ◽

Author(s):

Karl-Peter Giese

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Procedural Learning ◽

Faculty Opinions recommendation of Modulation of gamma-secretase reduces beta-amyloid deposition in a transgenic mouse model of Alzheimer's disease.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.5594956.5560054 ◽

2010 ◽

Author(s):

Riqiang Yan

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Beta Amyloid ◽

Transgenic Mouse Model ◽

Amyloid Deposition ◽

Gamma Secretase ◽

High‐Fat Diet Modulates Hepatic Amyloid β and Cerebrosterol Metabolism in the Triple Transgenic Mouse Model of Alzheimer’s Disease

Hepatology Communications ◽

10.1002/hep4.1609 ◽

2020 ◽

Author(s):

Cristina R. Bosoi ◽

Milène Vandal ◽

Marine Tournissac ◽

Manon Leclerc ◽

Hortense Fanet ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

High Fat Diet ◽

Amyloid Β ◽

Transgenic Mouse Model ◽

High Fat ◽

Triple Transgenic Mouse

Decreased Glucose Metabolism and Glutamine Synthesis in the Retina of a Transgenic Mouse Model of Alzheimer’s Disease

Cellular and Molecular Neurobiology ◽

10.1007/s10571-021-01126-y ◽

2021 ◽

Author(s):

Anna Luna Mølgaard Tams ◽

Berta Sanz-Morello ◽

Emil Winther Westi ◽

Zaynab Ahmad Mouhammad ◽

Jens Velde Andersen ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Glucose Metabolism ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Glutamine Synthesis

Naphthalene Monoimide Derivative Ameliorates Amyloid Burden and Cognitive Decline in a Transgenic Mouse Model of Alzheimer's Disease

Advanced Therapeutics ◽

10.1002/adtp.202000225 ◽

2021 ◽

pp. 2000225

Author(s):

Sourav Samanta ◽

Kolla Rajasekhar ◽

Madhu Ramesh ◽

Natarajan Arul Murugan ◽

Shadab Alam ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Cognitive Decline ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Amyloid Burden ◽

Wide-Ranging Effects on the Brain Proteome in a Transgenic Mouse Model of Alzheimer’s Disease Following Treatment with a Brain-Targeting Somatostatin Peptide

ACS Chemical Neuroscience ◽

10.1021/acschemneuro.1c00303 ◽

2021 ◽

Author(s):

Fadi Rofo ◽

Friederike A. Sandbaumhüter ◽

Aikaterini Chourlia ◽

Nicole G. Metzendorf ◽

Jamie I. Morrison ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Brain Targeting ◽

Brain Proteome ◽

The Brain

Genetic ablation of the p66Shc adaptor protein reverses cognitive deficits and improves mitochondrial function in an APP transgenic mouse model of Alzheimer’s disease

Molecular Psychiatry ◽

10.1038/mp.2016.112 ◽

2016 ◽

Vol 22 (4) ◽

pp. 605-614 ◽

Cited By ~ 13

Author(s):

R Derungs ◽

G G Camici ◽

R D Spescha ◽

T Welt ◽

C Tackenberg ◽

...

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Cognitive Deficits ◽

Mitochondrial Function ◽

Adaptor Protein ◽

Transgenic Mouse Model ◽

Genetic Ablation ◽

EGb 761 enhances adult hippocampal neurogenesis and phosphorylation of CREB in transgenic mouse model of Alzheimer's disease

The FASEB Journal ◽

10.1096/fj.06-7649com ◽

2007 ◽

Vol 21 (10) ◽

pp. 2400-2408 ◽

Cited By ~ 103

Author(s):

Flaubert Tchantchou ◽

Yanan Xu ◽

Yanjue Wu ◽

Yves Christen ◽

Yuan Luo

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Hippocampal Neurogenesis ◽

Adult Hippocampal Neurogenesis ◽

Egb 761 ◽

P1-081: Memantine reduces amyloid and Tau pathologies in a triple-transgenic mouse model of Alzheimer's disease

Alzheimer s & Dementia ◽

10.1016/j.jalz.2008.05.667 ◽

2008 ◽

Vol 4 ◽

pp. T230-T230

Author(s):

Kim N. Green ◽

Hilda Martinez-Coria ◽

Pradeep K. Banerjee ◽

Sandeep Gupta ◽

Frank M. LaFerla

Keyword(s):

Alzheimer’S Disease ◽

Alzheimer's Disease ◽

Mouse Model ◽

Transgenic Mouse ◽

Transgenic Mouse Model ◽

Triple Transgenic Mouse