scholarly journals Long-term quality of life and functional impairment after decompressive craniectomy for malignant middle cerebral artery infarction

2014 ◽  
Vol 57 ◽  
pp. e22
Author(s):  
M. Sevin ◽  
D. Devos ◽  
A. Stefan ◽  
N. Gavrylova ◽  
G. Marc ◽  
...  
2014 ◽  
Vol 22 (1) ◽  
pp. 6-14 ◽  
Author(s):  
Jarle Sundseth ◽  
Antje Sundseth ◽  
Bente Thommessen ◽  
Lars G. Johnsen ◽  
Marianne Altmann ◽  
...  

2009 ◽  
Vol 256 (7) ◽  
pp. 1126-1133 ◽  
Author(s):  
Bessy Benejam ◽  
Juan Sahuquillo ◽  
Maria Antonia Poca ◽  
Laura Frascheri ◽  
Elisabeth Solana ◽  
...  

2014 ◽  
Vol 10 (2) ◽  
pp. 170-176 ◽  
Author(s):  
Tessa van Middelaar ◽  
Paul J. Nederkoorn ◽  
H. Bart van der Worp ◽  
Jan Stam ◽  
Edo Richard

2021 ◽  
Author(s):  
Alex Vicino ◽  
Philippe Vuadens ◽  
Bertrand Léger ◽  
Charles Benaim

Abstract PurposeDecompressive craniectomy (DC) can rapidly reduce intracranial pressure and save lives in the acute phase of severe traumatic brain injury (TBI) or stroke, but little is known about the long-term outcome after DC. We evaluated quality of life (QoL) a few years after DC for severe TBI/stroke.MethodsThe following data were collected for stroke/TBI patients hospitalized for neurorehabilitation after DC: 1) at discharge, motor and cognitive sub-scores of the Functional Independence Measure (motor-FIM [score 13-91] and cognitive-FIM [score 5-35]) and 2) more than 4 years after discharge, the QOLIBRI health-related QoL (HR-QoL) score (0-100; <60 representing low or impaired QoL) and the return to work (RTW: 0%, partial, 100%)ResultsWe included 88 patients (66 males, median age 38 [interquartile range 26.3-51.0], 65 with TBI/23 stroke); 46 responded to the HR-QoL questionnaire. Responders and non-responders had similar characteristics (age, sex, functional levels upon discharge). Median motor-FIM and cognitive-FIM scores were 85/91 and 27/35, with no significant difference between TBI and stroke patients. Long-term QoL was borderline low for TBI patients and within normal values for stroke patients (score 58.0[42.0-69.0] vs. 67.0[54.0-81.5], p=0.052). RTW was comparable between the groups (62% full time).ConclusionWe already knew that DC can save the lives of TBI or stroke patients in the acute phase and this study suggests that their long-term quality of life is generally quite acceptable.


Neurosurgery ◽  
2020 ◽  
Vol 86 (3) ◽  
pp. E318-E325 ◽  
Author(s):  
Taco Goedemans ◽  
Dagmar Verbaan ◽  
Bert A Coert ◽  
Bertjan Kerklaan ◽  
René van den Berg ◽  
...  

Abstract BACKGROUND Based on randomized controlled trials (RCTs), clinical guidelines for the treatment of space-occupying hemispheric infarct employ age (≤60 yr) and time elapsed since stroke onset (≤48 h) as decisive criteria whether to perform decompressive craniectomy (DC). However, only few patients in these RCTs underwent DC after 48 h. OBJECTIVE To study the association between the timing of DC and (un)favorable outcome in patients with space-occupying middle cerebral artery (MCA) infarct undergoing DC. METHODS We performed a single-center cohort study from 2007 to 2017. Unfavorable outcome at 1 yr was defined as a Glasgow outcome scale 1 to 3. Additionally, we systematically reviewed the literature up to November 2018, including studies reporting on the timing of DC and other predictors of outcome. We performed Firth penalized likelihood and random-effects meta-analysis with odds ratio (OR) on unfavorable outcome. RESULTS A total of 66 patients were enrolled. A total of 26 (39%) patients achieved favorable and 40 (61%) unfavorable outcomes (13 [20%] died). DC after 48 h since stroke diagnosis did not significantly increase the risk of unfavorable outcome (OR 0.8, 95% CI 0.3-2.3). Also, in the meta-analysis, DC after 48 h of stroke onset was not associated with a higher risk of unfavorable outcome (OR 1.11; 95% CI 0.89-1.38). CONCLUSION The outcome of DC performed after 48 h in patients with malignant MCA infarct was not worse than the outcome of DC performed within 48 h. Contrary to current guidelines, we, therefore, advocate not to set a restriction of ≤48 h on the time elapsed since stroke onset in the decision whether to perform DC.


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