scholarly journals Efficacy of chitinase-3-like protein 1 as an in vivo bone formation predictable marker of maxillary/mandibular bone marrow stromal cells

2021 ◽  
Vol 18 ◽  
pp. 38-50
Author(s):  
Naohiro Komabashiri ◽  
Fumio Suehiro ◽  
Masakazu Ishii ◽  
Masahiro Nishimura
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Mandibular Bone ◽  
In Vivo Bone Formation

In vivo bone formation by human bone marrow stromal cells: Effect of carrier particle size and shape

2000 ◽  
Vol 72 (1) ◽  
pp. 96-107 ◽  
Author(s):  
Mahesh H. Mankani ◽  
Sergei A. Kuznetsov ◽  
Bruce Fowler ◽  
Albert Kingman ◽  
Pamela Gehron Robey
Keyword(s):  
Bone Marrow ◽  
Particle Size ◽  
Bone Formation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Particle Size And Shape ◽  
In Vivo Bone Formation

scholarly journals Association between in vivo bone formation and ex vivo migratory capacity of human bone marrow stromal cells

2015 ◽  
Vol 6 (1) ◽  
Author(s):  
Rikke K. Andersen ◽  
Walid Zaher ◽  
Kenneth H. Larsen ◽  
Nicholas Ditzel ◽  
Katharina Drews ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Ex Vivo ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Migratory Capacity ◽  
In Vivo Bone Formation

In Vivo Bone Formation by Human Bone Marrow Stromal Cells: Reconstruction of the Mouse Calvarium and Mandible

Stem Cells ◽  
2006 ◽  
Vol 24 (9) ◽  
pp. 2140-2149 ◽  
Author(s):  
Mahesh H. Mankani ◽  
Sergei A. Kuznetsov ◽  
Raymond M. Wolfe ◽  
Grayson W. Marshall ◽  
Pamela Gehron Robey
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Human Bone ◽  
Human Bone Marrow ◽  
In Vivo Bone Formation

Cbfa1/osf2 Transduced Bone Marrow Stromal Cells Facilitate Bone Formation In Vitro and In Vivo

2004 ◽  
Vol 74 (2) ◽  
pp. 194-203 ◽  
Author(s):  
H. Zheng ◽  
Z. Guo ◽  
Q. Ma ◽  
H. Jia ◽  
G. Dang
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells

scholarly journals Periostin Mediates Oestrogen-Induced Osteogenic Differentiation of Bone Marrow Stromal Cells in Ovariectomised Rats

2020 ◽  
Vol 2020 ◽  
pp. 1-10
Author(s):  
Chunrong Li ◽  
Xin Li ◽  
Xian Wang ◽  
Pei Miao ◽  
Jia Liu ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Bone Formation ◽  
Osteogenic Differentiation ◽  
Stromal Cells ◽  
Bone Marrow Stromal Cells ◽  
Marrow Stromal Cells ◽  
Ovx Rats ◽  
Novel Target

Osteoporosis is a metabolic disease that results in the progressive loss of bone mass, which, in postmenopausal women, is related to oestrogen deficiency. Periostin (POSTN) plays a key role in the early stages of bone formation. However, whether POSTN participates in oestradiol regulation of osteogenic differentiation of bone marrow stromal cells (BMSCs) from ovariectomised (OVX) rats remains unclear. In vivo, using microcomputed tomography (micro-CT), immunohistochemistry, and dynamic analysis of femurs, we found that 17β-E2 promotes bone formation and POSTN expression at the endosteal surface. In vitro, 17β-E2 upregulated POSTN expression in OVX-BMSCs. POSTN overexpression activated the Wnt/β-catenin signalling pathway and enhanced osteogenic differentiation of OVX-BMSCs. Furthermore, knockdown of Postn blocks the involvement of 17β-E2 in the osteogenic differentiation of OVX-BMSCs. Collectively, our study indicated the role of POSTN in the osteogenesis and stemness of OVX-BMSCs and proves that 17β-E2 reduces osteoporosis and promotes osteogenesis through the POSTN-Wnt/β-catenin pathway. POSTN could, therefore, be a novel target gene for anti-osteoporosis therapies.

Sign in / Sign up

Export Citation Format

Share Document