A Highly Sensitive Switch-on Spectrofluorometric Method for Determination of Ascorbic Acid Using a Selective Eco-Friendly Approach

2021 ◽  
pp. 120802
Author(s):  
Samah F. El-Malla ◽  
Rehab H. Elattar ◽  
Amira H. Kamal ◽  
Fotouh R. Mansour
Keyword(s):  
Ascorbic Acid ◽  
Highly Sensitive ◽  
Spectrofluorometric Method

scholarly journals A highly sensitive biosensor based on methacrylated graphene oxide-grafted polyaniline for ascorbic acid determination

2020 ◽  
Vol 9 (1) ◽  
pp. 760-767 ◽  
Author(s):  
Seyed Morteza Naghib ◽  
Farahnaz Behzad ◽  
Mehdi Rahmanian ◽  
Yasser Zare ◽  
Kyong Yop Rhee
Keyword(s):  
Ascorbic Acid ◽  
Graphene Oxide ◽  
Current Response ◽  
Functionalized Graphene ◽  
Serum Samples ◽  
Promising Candidate ◽  
Graphene Nanocomposites ◽  
Selective Determination ◽  
Highly Sensitive

AbstractFunctionalized graphene-based nanocomposites have opened new windows to address some challenges for increasing the sensitivity, accuracy and functionality of biosensors. Polyaniline (PANI) is one of the most potentially promising and technologically important conducting polymers, which brings together the electrical features of metals with intriguing properties of plastics including facile processing and controllable chemical and physical properties. PANI/graphene nanocomposites have attracted intense interest in various fields due to unique physicochemical properties including high conductivity, facile preparation and intriguing redox behavior. In this article, a functionalized graphene-grafted nanostructured PANI nanocomposite was applied for determining the ascorbic acid (AA) level. A significant current response was observed after treating the electrode surface with methacrylated graphene oxide (MeGO)/PANI nanocomposite. The amperometric responses showed a robust linear range of 8–5,000 µM and detection limit of 2 µM (N = 5). Excellent sensor selectivity was demonstrated in the presence of electroactive components interfering species, commonly found in real serum samples. This sensor is a promising candidate for rapid and selective determination of AA.

Automated Fluorometric Method for the Determination of Total Vitamin C in Food Products

1976 ◽  
Vol 59 (6) ◽  
pp. 1244-1250 ◽  
Author(s):  
Ram B Roy ◽  
Aldo Conetta ◽  
Jerry Salpeter
Keyword(s):  
Ascorbic Acid ◽  
Vitamin C ◽  
Dehydroascorbic Acid ◽  
Food Products ◽  
Total Vitamin ◽  
Automated Method ◽  
Highly Sensitive ◽  
Aoac Method ◽  
Analytical System

Abstract A specific microfluorometric method for the determination of ascorbic acid, dehydroascorbic acid, and total vitamin C in food products has been automated. The procedure developed is an adaptation of the official AOAC method (secs. 43.056–43.062), except that N-bromosuccinimide is used instead of Norit to oxidize vitamin C. Ascorbic acid is selectively oxidized by N-bromosuccinimide before other interfering substances that may be present, so this method is a highly sensitive and specific technique with extensive applicability. The proposed automated method is simple, rapid, reliable, and sufficiently sensitive to analyze as little as 2 × 10−3 to 0.1 mg ascorbic acid/ml. Analytical results obtained for ascorbic acid, dehydroascorbic acid, and total vitamin C in a wide variety of food products are reported. The analytical system developed has the capability of analyzing 50 samples/hr.

scholarly journals A Highly Sensitive Spectrofluorometric Method for the Determination of a New Antidepressant Drug, Reboxetine, in Tablets

2006 ◽  
Vol 89 (4) ◽  
pp. 972-975 ◽  
Author(s):  
ArmaĞan Önal
Keyword(s):  
Antidepressant Drug ◽  
Fluorescence Emission ◽  
Calibration Graph ◽  
Control Analysis ◽  
Optimum Conditions ◽  
Highly Sensitive ◽  
Relative Standard ◽  
Spectrofluorometric Method ◽  
Interday Precision

Abstract A highly sensitive, selective, and rapid spectrofluorometric method has been developed for the determination of reboxetine (REB) in tablets. The method is based on derivatization with 7-chloro-4-nitrobenzofurazan. The product showed an absorption maximum at 476 nm and a fluorescence emission peak at 533 nm in ethyl acetate. The optimum conditions of the reaction were investigated, and it was found that the reaction proceeded quantitatively at pH 8.5, 70C in 5 min. The calibration graph is rectilinear over the range of 0.02-0.40 μg/mL. The relative standard deviation values for intraday and interday precision were 0.40-0.93 and 0.54-1.37%, respectively. The proposed method was applied to the assay of REB in tablets. Mean recovery of REB from the tablets ranged between 99.91-100.20%. The results were compared statistically with those obtained by a method reported in the literature. The method is sensitive, simple, and selective, and can be used for routine quality control analysis.

scholarly journals Utilization of a new gold/Schiff-base iron(iii) complex composite as a highly sensitive voltammetric sensor for determination of epinephrine in the presence of ascorbic acid

RSC Advances ◽  
2016 ◽  
Vol 6 (104) ◽  
pp. 101888-101899 ◽  
Author(s):  
Adam Gorczyński ◽  
Maciej Kubicki ◽  
Klaudia Szymkowiak ◽  
Teresa Łuczak ◽  
Violetta Patroniak
Keyword(s):  
Ascorbic Acid ◽  
Schiff Base ◽  
Schiff Base Complex ◽  
Voltammetric Sensor ◽  
Base Complex ◽  
Highly Sensitive

A new voltammetric sensor based on an iron(iii) Schiff-base complex/Au composite is synthesized and applied for the in vitro detection of epinephrine.

Highly sensitive and selective electrochemical determination of dopamine and ascorbic acid at Ag/Ag2S modified electrode

2011 ◽  
Vol 56 (5) ◽  
pp. 1955-1959 ◽  
Author(s):  
Chen-Yan Li ◽  
Ying-Jie Cai ◽  
Chien-Hsin Yang ◽  
Chen-Hao Wu ◽  
Yen Wei ◽  
...  
Keyword(s):  
Ascorbic Acid ◽  
Modified Electrode ◽  
Electrochemical Determination ◽  
Highly Sensitive
Sign in / Sign up

Export Citation Format

Share Document