Effective connectivity within a triple network brain system discriminates schizophrenia spectrum disorders from psychotic bipolar disorder at the single-subject level

2019 ◽  
Vol 214 ◽  
pp. 24-33 ◽  
Author(s):  
Lena Palaniyappan ◽  
Gopikrishna Deshpande ◽  
Pradyumna Lanka ◽  
D. Rangaprakash ◽  
Sarina Iwabuchi ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Effective Connectivity ◽  
Single Subject ◽  
Schizophrenia Spectrum Disorders ◽  
Brain System ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
Psychotic Bipolar Disorder

Cerebellar Structure Across Early and Chronic Stages of Illness in Schizophrenia Spectrum Disorders and Psychotic Bipolar Disorder

2021 ◽  
Vol 89 (9) ◽  
pp. S179-S180
Author(s):  
Alexandra Moussa-Tooks ◽  
Anna Huang ◽  
Baxter Rogers ◽  
Julia Sheffield ◽  
Jennifer Blackford ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
Psychotic Bipolar Disorder

Altered systemic cortisol metabolism in bipolar disorder and schizophrenia spectrum disorders

2014 ◽  
Vol 52 ◽  
pp. 57-62 ◽  
Author(s):  
Nils Eiel Steen ◽  
Paal Methlie ◽  
Steinar Lorentzen ◽  
Ingrid Dieset ◽  
Monica Aas ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Schizophrenia Spectrum Disorders ◽  
Cortisol Metabolism ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders

scholarly journals Abnormal bodily experiences detected by Abnormal Bodily Phenomena questionnaire are more frequent and severe in schizophrenia than in bipolar disorder with psychotic features

2020 ◽  
Vol 63 (1) ◽  
Author(s):  
Giovanni Stanghellini ◽  
Davide Palumbo ◽  
Massimo Ballerini ◽  
Armida Mucci ◽  
Francesco Catapano ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Internal Consistency ◽  
Convergent Validity ◽  
Type I ◽  
Semistructured Interview ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Bodily Experiences ◽  
Spectrum Disorders ◽  
Psychotic Features

Abstract Background: Patients with schizophrenia display experiential anomalies in their feelings and cognitions arising in the domain of their lived body. These abnormal bodily phenomena (ABP) are not part of diagnostic criteria for schizophrenia. One of the reasons is the difficulty to assess specific ABP for schizophrenia spectrum disorders. The present study aimed to explore the presence in patients with schizophrenia of specific ABP. Methods: We used a semistructured interview—the Abnormal Bodily Phenomena questionnaire (ABPq), an instrument devised to detect and measure ABP specific to patients with schizophrenia. Fifty-one outpatients affected by schizophrenia and 28 euthymic outpatients affected by bipolar disorder type I with psychotic features (BD-pf-e) were recruited. Before assessing the specificity for schizophrenia of the observed ABP, we tested the internal consistency and the convergent validity of the ABPq in patients with schizophrenia. Specificity was assessed by examining potential differences in ABPq among the patients with schizophrenia in remission (SCZ-r) and BD-pf-e. Results: The ABPq shows strong internal consistency and convergent validity. As to the specificity, ABP measured by ABPq were more frequent and severe in SCZ-r than in BD-pf-e. In particular, all ABPq dimensions, except “Coherence,” had at least mild severity in over 50% of SCZ-r, while dimensions with at least mild severity were observed in 5–10% of the BD-pf-e. Conclusions: These findings can contribute to establish more precise phenomenal boundaries between schizophrenia and bipolar disorder, to explore the borders between nonpsychotic and psychotic forms of ABP, between ABP and negative and disorganized symptoms, and to enlighten core aspects of schizophrenia.

Attributions for Hallucinations in Bipolar Affective Disorder

2010 ◽  
Vol 38 (2) ◽  
pp. 221-226 ◽  
Author(s):  
Paul Hammersley ◽  
Katherine Taylor ◽  
John McGovern ◽  
Peter Kinderman
Keyword(s):  
Bipolar Disorder ◽  
Mood State ◽  
Bipolar Affective Disorder ◽  
Bipolar Disorders ◽  
Auditory Hallucinations ◽  
Schizophrenia Spectrum Disorders ◽  
Schizophrenia Spectrum ◽  
Preliminary Study ◽  
Randomized Control ◽  
Spectrum Disorders

Background: Attributions for hallucinations in the “schizophrenia” spectrum disorders have been subject to extensive investigation; however, in comparison very little is known about attributions for hallucinations in the bipolar disorders spectrum. Aims: This preliminary study is an attempt to investigate attributions for hallucinations in bipolar disorder with regard to prevalence, modality and mood state. Method: Forty participants were recruited from a larger randomized control trial into CBT for bipolar disorder and asked to provide information related to attributions for hallucinations both in and out of episode. Data was collected using a specially designed instrument based on the Belief about Voices Questionnaire (BAVQ). Results: Just under half of the participants reported experiencing true hallucinations during their illness. Participants tended to report visual hallucinations in mania and auditory hallucinations in depression. The vast majority of participants attributed hallucinations to illness when out of episode, and unlike in previously reported analyses of attributions for hallucinations in the schizophrenia spectrum, malevolent/omnipotent attributions were comparatively rare. Conclusions: Attributions for hallucinations in bipolar disorder may be clinically distinct from attributions previously observed in the schizophrenia spectrum, and CBT aimed at reducing the distress associated with these attributions may have to be tailored accordingly.

Sustained Attention and Visual Processing Speed in Children and Adolescents with Bipolar Disorder and other Psychiatric Disorders

2004 ◽  
Vol 95 (1) ◽  
pp. 39-47 ◽  
Author(s):  
James McCarthy ◽  
Alexandra McGlashan ◽  
Keith Kraseski ◽  
Diana Arrese ◽  
Brad Rappaport ◽  
...  
Keyword(s):  
Bipolar Disorder ◽  
Conduct Disorder ◽  
Visual Processing ◽  
Digit Span ◽  
Schizophrenia Spectrum Disorders ◽  
Oppositional Defiant ◽  
Not Otherwise Specified ◽  
Schizophrenia Spectrum ◽  
Spectrum Disorders ◽  
Visual Processing Speed

To investigate the cognitive functioning of children and adolescents with bipolar illness, 112 child and adolescent psychiatric inpatients and day-hospital patients at a state psychiatric hospital were administered the Wechsler Intelligence Scale for Children–III (WISC–III) as part of an admission psychological assessment. There were 22 patients with Bipolar Disorder and 90 with other psychiatric disorders; all were between 8 and 17 years of age. The patients with Bipolar Disorder had a mean age of 14 yr., a mean Verbal IQ of 78, a mean Performance IQ of 76, and a mean Full Scale IQ of 75. When their WISC–III scores were compared with those who had Schizophrenia Spectrum disorders (Schizophrenia and Schizoaffective Disorder), Psychosis Not Otherwise Specified, Attention Deficit Hyperactivity Disorder, and Conduct Disorder and Oppositional Defiant Disorder, there were no significant between-group mean differences for Verbal IQ, but patients with Bipolar Disorder had a significantly lower mean Performance IQ than those with ADHD and those with Conduct Disorder and Oppositional Defiant Disorder. Contrary to the expectation that the patients with Bipolar Disorder might have better sustained attention (higher Digit Span scores) than those with Schizophrenia Spectrum disorders and worse visual processing speed (lower Coding scores) than the other diagnostic groups, the bipolar patients' Digit Span and Coding scores did not differ significantly from those of the other groups. The patients with Psychosis, Not Otherwise Specified had significantly lower mean Performance IQ, Full Scale IQ, and Coding than the ADHD and the Conduct Disorder and Oppositional Disorder groups.

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