Sleep spindles and slow wave activity are associated with sleep-dependent memory consolidation in healthy older adults and obstructive sleep apnoea

2019 ◽  
Vol 64 ◽  
pp. S378
Author(s):  
J.Z. Teh ◽  
L. Grummit ◽  
C. Haroutonian ◽  
N. Cross ◽  
B. Skinner ◽  
...  
2010 ◽  
Vol 37 (5) ◽  
pp. 1144-1150 ◽  
Author(s):  
N. Ben-Israel ◽  
Y. Zigel ◽  
A. Tal ◽  
Y. Segev ◽  
A. Tarasiuk

2017 ◽  
Vol 27 (4) ◽  
pp. 389-402 ◽  
Author(s):  
Nathan Cross ◽  
Amit Lampit ◽  
Jonathon Pye ◽  
Ronald R. Grunstein ◽  
Nathaniel Marshall ◽  
...  

2015 ◽  
Vol 8 (3) ◽  
pp. 520-527 ◽  
Author(s):  
Peter Garside ◽  
Joseph Arizpe ◽  
Chi-Ieong Lau ◽  
Crystal Goh ◽  
Vincent Walsh

2018 ◽  
Vol 52 (1) ◽  
pp. 1800740 ◽  
Author(s):  
Nathan E. Cross ◽  
Negar Memarian ◽  
Shantel L. Duffy ◽  
Casey Paquola ◽  
Haley LaMonica ◽  
...  

This study aimed to investigate associations between obstructive sleep apnoea (OSA) and cortical thickness in older adults with subjective and objective cognitive difficulties, who are considered “at-risk” for dementia.83 middle-aged to older adults (51–88 years) underwent neuropsychological testing, polysomnography assessment of OSA and a structural magnetic resonance imaging brain scan. A principal components analysis was performed on OSA measures. Cortical thickness and subcortical volumes were compared to extracted components of “oxygen desaturation” and “sleep disturbance”.Oxygen desaturation was significantly related to reduced cortical thickness in the bilateral temporal lobes (left: r=−0.44, p<0.001; right: r=−0.39, p=0.003). Conversely, sleep disturbance was associated with increased thickness in the right postcentral gyrus (r=0.48, p<0.001), pericalcarine (r=0.50, p=0.005) and pars opercularis (r=0.46, p=0.009) and increased volume of the hippocampus and amygdala. Decreased thickness in the bilateral temporal regions was associated with reduced verbal encoding (r=0.28, p=0.010).Given the clinical significance of this sample in terms of dementia prevention, these changes in grey matter reveal how OSA might contribute to neurodegenerative processes in older adults.


Thorax ◽  
2009 ◽  
Vol 65 (2) ◽  
pp. 107-112 ◽  
Author(s):  
R. Ratnavadivel ◽  
D. Stadler ◽  
S. Windler ◽  
J. Bradley ◽  
D. Paul ◽  
...  

2014 ◽  
Vol 15 (9) ◽  
pp. 1037-1045 ◽  
Author(s):  
Evan D. Chinoy ◽  
Danielle J. Frey ◽  
Daniel N. Kaslovsky ◽  
Francois G. Meyer ◽  
Kenneth P. Wright

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