scholarly journals Age-related changes in slow wave activity rise time and NREM sleep EEG with and without zolpidem in healthy young and older adults

2014 ◽  
Vol 15 (9) ◽  
pp. 1037-1045 ◽  
Author(s):  
Evan D. Chinoy ◽  
Danielle J. Frey ◽  
Daniel N. Kaslovsky ◽  
Francois G. Meyer ◽  
Kenneth P. Wright
Keyword(s):  
Older Adults ◽  
Slow Wave ◽  
Rise Time ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Sleep Eeg ◽  
Age Related ◽  
Age Related Changes

scholarly journals Reduced Regional NREM Sleep Slow-Wave Activity Is Associated With Cognitive Impairment in Parkinson Disease

2021 ◽  
Vol 12 ◽  
Author(s):  
Simon J. Schreiner ◽  
Lukas L. Imbach ◽  
Philipp O. Valko ◽  
Angelina Maric ◽  
Rina Maqkaj ◽  
...  
Keyword(s):  
Cognitive Impairment ◽  
Parkinson Disease ◽  
Slow Wave ◽  
Slow Wave Sleep ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Dependent Manner ◽  
Age Related

Growing evidence implicates a distinct role of disturbed slow-wave sleep in neurodegenerative diseases. Reduced non-rapid eye movement (NREM) sleep slow-wave activity (SWA), a marker of slow-wave sleep intensity, has been linked with age-related cognitive impairment and Alzheimer disease pathology. However, it remains debated if SWA is associated with cognition in Parkinson disease (PD). Here, we investigated the relationship of regional SWA with cognitive performance in PD. In the present study, 140 non-demented PD patients underwent polysomnography and were administered the Montréal Cognitive Assessment (MoCA) to screen for cognitive impairment. We performed spectral analysis of frontal, central, and occipital sleep electroencephalography (EEG) derivations to measure SWA, and spectral power in other frequency bands, which we compared to cognition using linear mixed models. We found that worse MoCA performance was associated with reduced 1–4 Hz SWA in a region-dependent manner (F2, 687 =11.67, p < 0.001). This effect was driven by reduced regional SWA in the lower delta frequencies, with a strong association of worse MoCA performance with reduced 1–2 Hz SWA (F2, 687 =18.0, p < 0.001). The association of MoCA with 1–2 Hz SWA (and 1–4 Hz SWA) followed an antero-posterior gradient, with strongest, weaker, and absent associations over frontal (rho = 0.33, p < 0.001), central (rho = 0.28, p < 0.001), and occipital derivations, respectively. Our study shows that cognitive impairment in PD is associated with reduced NREM sleep SWA, predominantly in lower delta frequencies (1–2 Hz) and over frontal regions. This finding suggests a potential role of reduced frontal slow-wave sleep intensity in cognitive impairment in PD.

K-complexes and slow wave activity during nrem sleep in patients with Alzheimer's disease

2017 ◽  
Vol 40 ◽  
pp. e115-e116
Author(s):  
M. Gorgoni ◽  
F. Reda ◽  
G. Lauri ◽  
I. Truglia ◽  
S. Cordone ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Slow Wave ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity

scholarly journals Dynamics of Slow-Wave Activity During the NREM Sleep of Sleepwalkers and Control Subjects

SLEEP ◽  
2000 ◽  
Vol 23 (6) ◽  
pp. 1-6 ◽  
Author(s):  
Hélène Gaudreau ◽  
Steve Joncas ◽  
Antonio Zadra ◽  
Jacques Montplaisir
Keyword(s):  
Slow Wave ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Control Subjects ◽  
And Control

Interleukin-1 derived from astrocytes enhances slow wave activity in sleep EEG of the rat

1984 ◽  
Vol 104 (1-2) ◽  
pp. 191-192 ◽  
Author(s):  
Irene Tobler ◽  
Alexander A. Borbély ◽  
Martin Schwyzer ◽  
Adriano Fontana
Keyword(s):  
Slow Wave ◽  
Interleukin 1 ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Sleep Eeg

scholarly journals Relationship of sleep homeostasis to seizures and cognition in children with focal epilepsy

2020 ◽  
Author(s):  
Maria H Eriksson ◽  
Torsten Baldeweg ◽  
Ronit Pressler ◽  
Stewart G Boyd ◽  
Reto Huber ◽  
...  
Keyword(s):  
Slow Wave ◽  
Focal Epilepsy ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Iq Testing ◽  
Sleep Homeostasis ◽  
Interictal Discharges ◽  
Relationship Of ◽  
The Relationship

AbstractObjectiveSleep disruption and cognitive impairment are important co-morbidities in childhood epilepsy, yet a mechanistic link has not been substantiated. Slow wave activity during sleep and its homeostatic decrease across the night is associated with synaptic renormalisation, and shows maturational changes over the course of childhood. Here, we aimed to investigate the effect of epilepsy on sleep homeostasis in the developing brain.MethodsWe examined the relationship of sleep homeostasis as reflected in slow wave activity to seizures, cognition and behaviour, comparing 22 children (aged 6 to 16 years) with focal epilepsy to 21 age-matched healthy controls. Participants underwent overnight sleep EEG and IQ testing and performed memory consolidation tasks. Their parents completed standard behavioural questionnaires.ResultsChildren with epilepsy had lower slow wave activity at the start of non-rapid eye movement (NREM) sleep, though similar overnight decline and slow wave activity in the final hour of NREM sleep. Both groups displayed an antero-posterior shift in peak slow wave activity overnight, though individual patients showed persistent local increases at scalp locations matching those of focal interictal discharges. Patients who had seizures during their admission had lower early-night slow wave activity, the group without seizures showing similar activity to controls. We found a positive correlation between full scale IQ and early-night slow wave activity in patients but not controls.InterpretationReduced early night slow wave activity in children with focal epilepsies is correlated with lower cognitive ability and more seizures and may reflect a reduction in learning-related synaptic potentiation.

Deep sleep after social stress: NREM sleep slow-wave activity is enhanced in both winners and losers of a conflict

2015 ◽  
Vol 47 ◽  
pp. 149-154 ◽  
Author(s):  
Jeanine Kamphuis ◽  
Marike Lancel ◽  
Jaap M. Koolhaas ◽  
Peter Meerlo
Keyword(s):  
Slow Wave ◽  
Social Stress ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Slow Wave Activity ◽  
Deep Sleep

scholarly journals EEG sigma and slow-wave activity during NREM sleep correlate with overnight declarative and procedural memory consolidation

2012 ◽  
Vol 21 (6) ◽  
pp. 612-619 ◽  
Author(s):  
JOHANNES HOLZ ◽  
HANNAH PIOSCZYK ◽  
BERND FEIGE ◽  
KAI SPIEGELHALDER ◽  
CHIARA BAGLIONI ◽  
...  
Keyword(s):  
Slow Wave ◽  
Memory Consolidation ◽  
Nrem Sleep ◽  
Procedural Memory ◽  
Wave Activity ◽  
Slow Wave Activity

Slow-wave activity in NREM sleep: sex and age effects in depressed outpatients and healthy controls

2000 ◽  
Vol 95 (3) ◽  
pp. 201-213 ◽  
Author(s):  
Roseanne Armitage ◽  
Robert Hoffmann ◽  
Madhukar Trivedi ◽  
A.John Rush
Keyword(s):  
Slow Wave ◽  
Nrem Sleep ◽  
Wave Activity ◽  
Age Effects ◽  
Slow Wave Activity ◽  
Healthy Controls ◽  
Sleep Sex
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