Recent progress in solid-state NMR studies of drugs confined within drug delivery systems

2014 ◽  
Vol 57-58 ◽  
pp. 2-16 ◽  
Author(s):  
Ewa Skorupska ◽  
Agata Jeziorna ◽  
Slawomir Kazmierski ◽  
Marek J. Potrzebowski
Molecules ◽  
2021 ◽  
Vol 26 (14) ◽  
pp. 4142
Author(s):  
Marianna Porcino ◽  
Xue Li ◽  
Ruxandra Gref ◽  
Charlotte Martineau-Corcos

In the past decades, nanosized drug delivery systems (DDS) have been extensively developed and studied as a promising way to improve the performance of a drug and reduce its undesirable side effects. DDSs are usually very complex supramolecular assemblies made of a core that contains the active substance(s) and ensures a controlled release, which is surrounded by a corona that stabilizes the particles and ensures the delivery to the targeted cells. To optimize the design of engineered DDSs, it is essential to gain a comprehensive understanding of these core–shell assemblies at the atomic level. In this review, we illustrate how solid-state nuclear magnetic resonance (ssNMR) spectroscopy has become an essential tool in DDS design.


Author(s):  
Wen-Jie Xu ◽  
Jia-Xin Cai ◽  
Yong-Jiang Li ◽  
Jun-Yong Wu ◽  
Daxiong Xiang

2017 ◽  
Vol 14 (3) ◽  
pp. 228 ◽  
Author(s):  
Yanru Xin ◽  
Mingming Yin ◽  
Liyuan Zhao ◽  
Fanling Meng ◽  
Liang Luo

2020 ◽  
Vol 153 (15) ◽  
pp. 154506
Author(s):  
Benjamin Malfait ◽  
Natália T. Correia ◽  
Carmen Ciotonea ◽  
Jérémy Dhainaut ◽  
Jean-Philippe Dacquin ◽  
...  

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