Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone

Xue-Feng Wu; Zi-Jun Ouyang; Li-Li Feng; Gong Chen; Wen-Jie Guo; Yan Shen; Xu-Dong Wu; Yang Sun; Qiang Xu

doi:10.1016/j.taap.2014.10.002

Suppression of NF-κB signaling and NLRP3 inflammasome activation in macrophages is responsible for the amelioration of experimental murine colitis by the natural compound fraxinellone

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2014.10.002 ◽

2014 ◽

Vol 281 (1) ◽

pp. 146-156 ◽

Cited By ~ 46

Author(s):

Xue-Feng Wu ◽

Zi-Jun Ouyang ◽

Li-Li Feng ◽

Gong Chen ◽

Wen-Jie Guo ◽

...

Keyword(s):

Nlrp3 Inflammasome ◽

Natural Compound ◽

Inflammasome Activation ◽

Murine Colitis ◽

Nlrp3 Inflammasome Activation

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Protective effects of wedelolactone on dextran sodium sulfate induced murine colitis partly through inhibiting the NLRP3 inflammasome activation via AMPK signaling

Biomedicine & Pharmacotherapy ◽

10.1016/j.biopha.2017.06.071 ◽

2017 ◽

Vol 94 ◽

pp. 27-36 ◽

Cited By ~ 9

Author(s):

Wencheng Wei ◽

Meiling Ding ◽

Kai Zhou ◽

Haifeng Xie ◽

Mian Zhang ◽

...

Keyword(s):

Nlrp3 Inflammasome ◽

Sodium Sulfate ◽

Dextran Sodium Sulfate ◽

Inflammasome Activation ◽

Protective Effects ◽

Ampk Signaling ◽

Murine Colitis ◽

Nlrp3 Inflammasome Activation

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Suppression of NLRP3 inflammasome activation in LPS‐induced RAW264.7 cells by natural compound Lava Spirulina maxima extract

The FASEB Journal ◽

10.1096/fasebj.2019.33.1_supplement.795.3 ◽

2019 ◽

Vol 33 (S1) ◽

Author(s):

Sungwoo Chei ◽

Ji‐Hyeon Song ◽

Young‐Jin Seo ◽

Kippeum Lee ◽

Heegu Jin ◽

...

Keyword(s):

Nlrp3 Inflammasome ◽

Natural Compound ◽

Raw264.7 Cells ◽

Inflammasome Activation ◽

Spirulina Maxima ◽

Nlrp3 Inflammasome Activation

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248-LB: Deficiency of APPL1 in Macrophages Triggers Adipose Tissue Inflammation and Insulin Resistance by Potentiating NLRP3 Inflammasome Activation

Diabetes ◽

10.2337/db19-248-lb ◽

2019 ◽

Vol 68 (Supplement 1) ◽

pp. 248-LB ◽

Cited By ~ 1

Author(s):

KELVIN K.L. WU ◽

AIMIN XU ◽

KENNETH K. CHENG

Keyword(s):

Insulin Resistance ◽

Adipose Tissue ◽

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Adipose Tissue Inflammation ◽

Tissue Inflammation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Non-transcriptional priming and deubiquitination regulate NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.717980435.793471692 ◽

2013 ◽

Author(s):

Laurel Lenz ◽

Rebecca Schmidt

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Omega-3 fatty acids prevent inflammation and metabolic disorder through inhibition of NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718039111.793480657 ◽

2013 ◽

Author(s):

Douglas Green ◽

Jennifer Martinez

Keyword(s):

Fatty Acids ◽

Nlrp3 Inflammasome ◽

Metabolic Disorder ◽

Inflammasome Activation ◽

Omega 3 Fatty Acids ◽

Omega 3 ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of 3,4-methylenedioxy-β-nitrostyrene inhibits NLRP3 inflammasome activation by blocking assembly of the inflammasome.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.718184539.793519737 ◽

2016 ◽

Author(s):

Eicke Latz

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Dimethyl fumarate ameliorates dextran sulfate sodium-induced murine experimental colitis by activating Nrf2 and suppressing NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726362863.793559823 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Dextran Sulfate ◽

Dextran Sulfate Sodium ◽

Experimental Colitis ◽

Dimethyl Fumarate ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of Hemin and cobalt protoporphyrin inhibit NLRP3 inflammasome activation by enhancing autophagy: A novel mechanism of inflammasome regulation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.726766143.793523875 ◽

2016 ◽

Author(s):

Mark A Williams

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation ◽

Cobalt Protoporphyrin

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Faculty Opinions recommendation of Cholesterol Homeostatic Regulator SCAP-SREBP2 Integrates NLRP3 Inflammasome Activation and Cholesterol Biosynthetic Signaling in Macrophages.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734279765.793559839 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Nlrp3 Inflammasome Activation

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Faculty Opinions recommendation of PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.734514948.793559815 ◽

2019 ◽

Author(s):

Paras Anand

Keyword(s):

Nlrp3 Inflammasome ◽

Inflammasome Activation ◽

Trans Golgi Network ◽

Nlrp3 Inflammasome Activation ◽

Golgi Network

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