The insulin-like growth factor-I receptor gene: a downstream target for oncogene and tumor suppressor action

Trends in Endocrinology and Metabolism ◽

10.1016/j.tem.2006.06.007 ◽

2006 ◽

Vol 17 (6) ◽

pp. 236-242 ◽

Author(s):

Haim Werner ◽

Sharon Maor

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Downstream Target ◽

Factor I ◽

Growth Factor I

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Transcriptional Activation of the Insulin-Like Growth Factor I Receptor Gene by the Kruppel-Like Factor 6 (KLF6) Tumor Suppressor Protein: Potential Interactions between KLF6 and p53

Endocrinology ◽

10.1210/en.2004-0173 ◽

2004 ◽

Vol 145 (8) ◽

pp. 3769-3777 ◽

Author(s):

Moran Rubinstein ◽

Gila Idelman ◽

Stephen R. Plymate ◽

Goutham Narla ◽

Scott L. Friedman ◽

...

Keyword(s):

Growth Factor ◽

Tumor Suppressor ◽

Transcriptional Activation ◽

Receptor Gene ◽

Tumor Suppressor Protein ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Potential Interactions

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Trinucleotide repeat polymorphism at the human insulin-like growth factor I receptor gene (IGF1R)

Nucleic Acids Research ◽

10.1093/nar/20.6.1427 ◽

1992 ◽

Vol 20 (6) ◽

pp. 1427-1427 ◽

Author(s):

R. Meloni ◽

F. Fougerousse ◽

C. Roudaut ◽

J.S. Beckmann

Keyword(s):

Growth Factor ◽

Human Insulin ◽

Trinucleotide Repeat ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Repeat Polymorphism ◽

Factor I ◽

Growth Factor I

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Regulation of Insulin-Like Growth Factor I Receptor Gene Expression in Normal and Pathological States

Advances in Experimental Medicine and Biology - Molecular Biology and Physiology of Insulin and Insulin-Like Growth Factors ◽

10.1007/978-1-4684-5949-4_24 ◽

1991 ◽

pp. 263-272 ◽

Author(s):

Haim Werner ◽

Bethel Stannard ◽

Mark A. Bach ◽

Charles T. Roberts ◽

Derek LeRoith

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Receptor Gene Expression

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Human Chorionic Gonadotropin Up-Regulates Insulin-Like Growth Factor-I Receptor Gene Expression of Leydig Cells*

Endocrinology ◽

10.1210/endo-129-6-2820 ◽

1991 ◽

Vol 129 (6) ◽

pp. 2820-2826 ◽

Author(s):

MADAN L. NAGPAL ◽

DELI WANG ◽

JO H. CALKINS ◽

WEIWEI CHANG ◽

TU LIN

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Chorionic Gonadotropin ◽

Human Chorionic Gonadotropin ◽

Leydig Cells ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Receptor Gene Expression

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Insulin-like growth factor I receptor gene expression during postnatal development of rabbit kidney

The Anatomical Record ◽

10.1002/(sici)1097-0185(199710)249:2<187::aid-ar5>3.0.co;2-v ◽

1997 ◽

Vol 249 (2) ◽

pp. 187-195 ◽

Author(s):

José L. Ojeda ◽

M. Teresa Berciano ◽

José I. Polanco ◽

Miguel Lafarga ◽

José C. Rodríguez-Rey

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Postnatal Development ◽

Receptor Gene ◽

Rabbit Kidney ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Receptor Gene Expression

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Increased expression of the insulin-like growth factor I receptor gene, IGF1R, in Wilms tumor is correlated with modulation of IGF1R promoter activity by the WT1 Wilms tumor gene product.

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.90.12.5828 ◽

1993 ◽

Vol 90 (12) ◽

pp. 5828-5832 ◽

Author(s):

H. Werner ◽

G. G. Re ◽

I. A. Drummond ◽

V. P. Sukhatme ◽

F. J. Rauscher ◽

...

Keyword(s):

Growth Factor ◽

Gene Product ◽

Promoter Activity ◽

Wilms Tumor ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Wilms Tumor Gene ◽

Factor I ◽

Growth Factor I ◽

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Extended silencing of the insulin-like growth factor-I receptor gene in MCF-7 cells by serial transfection with siRNA

Analytical Biochemistry ◽

10.1016/j.ab.2006.07.029 ◽

2006 ◽

Vol 357 (2) ◽

pp. 305-307 ◽

Author(s):

Clare McVittie ◽

Sahira Khalaf ◽

William Ogunkolade ◽

Kathryn McCarthy ◽

Chrissie Laban ◽

...

Keyword(s):

Growth Factor ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I ◽

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Insulin-like growth factor-I (IGF-I) and IGF-I receptor gene expression in the kidney of the chronically hypoinsulinemic rat and hyperinsulinemic rat

10.1016/0026-0495(95)90093-4 ◽

1995 ◽

Vol 44 (8) ◽

pp. 982-986 ◽

Author(s):

O. Weiss ◽

H. Anner ◽

I. Nephesh ◽

A. Alayoff ◽

M. Bursztyn ◽

...

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Factor I ◽

Igf I ◽

Growth Factor I ◽

Receptor Gene Expression

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Structural and functional analysis of the insulin-like growth factor I receptor gene promoter

Molecular Endocrinology ◽

10.1210/me.6.10.1545 ◽

1992 ◽

Vol 6 (10) ◽

pp. 1545-1558 ◽

Author(s):

H. Werner

Keyword(s):

Functional Analysis ◽

Growth Factor ◽

Receptor Gene ◽

Gene Promoter ◽

Insulin Like Growth Factor ◽

Factor I ◽

Growth Factor I

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Regulation of insulin-like growth factor I receptor gene expression by Sp1: physical and functional interactions of Sp1 at GC boxes and at a CT element

Molecular Endocrinology ◽

10.1210/me.9.9.1147 ◽

1995 ◽

Vol 9 (9) ◽

pp. 1147-1156 ◽

Author(s):

D. Beitner-Johnson

Keyword(s):

Gene Expression ◽

Growth Factor ◽

Receptor Gene ◽

Insulin Like Growth Factor ◽

Functional Interactions ◽

Factor I ◽

Growth Factor I ◽

Receptor Gene Expression

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