Oxidative C(Sp3)–H activation and C–N cleavage of N-methyl amines under transition-metal-free condition for synthesis of methylene-bridged bis-1,3-diketones

Tetrahedron ◽  
2014 ◽  
Vol 70 (12) ◽  
pp. 2195-2202 ◽  
Author(s):  
Xiaohu Wang ◽  
Yi Wang ◽  
Yu Yuan ◽  
Chun-Hui Xing
Keyword(s):  
Transition Metal ◽  
Free Condition ◽  
Metal Free

scholarly journals K2S2O8-Promoted Aryl Thioamides Synthesis from Aryl Aldehydes Using Thiourea as the Sulfur Source

Molecules ◽  
2018 ◽  
Vol 23 (9) ◽  
pp. 2225 ◽  
Author(s):  
Yongjun Bian ◽  
Xingyu Qu ◽  
Yongqiang Chen ◽  
Jun Li ◽  
Leng Liu
Keyword(s):  
Transition Metal ◽  
Functional Groups ◽  
Sulfur Atom ◽  
Coupling Reaction ◽  
Sulfur Source ◽  
Atom Transfer ◽  
Free Condition ◽  
Metal Free ◽  
Aryl Aldehydes ◽  
Three Component Coupling

Thiourea as a sulfur atom transfer reagent was applied for the synthesis of aryl thioamides through a three-component coupling reaction with aryl aldehydes and N,N-dimethylformamide (DMF) or N,N-dimethylacetamide (DMAC). The reaction could tolerate various functional groups and gave moderate to good yields of desired products under the transition-metal-free condition.

(Z)-Tetrahydrothiophene and (Z)-tetrahydrothiopyran synthesis through nucleophilic substitution and intramolecular cycloaddition of alkynyl halides and EtOCS2K

2019 ◽  
Vol 17 (31) ◽  
pp. 7315-7319 ◽  
Author(s):  
Xianglin Luo ◽  
Yibiao Li ◽  
Xiuwen Chen ◽  
Zhiyan Song ◽  
Junyi Liang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Nucleophilic Substitution ◽  
Thiyl Radical ◽  
Intramolecular Cycloaddition ◽  
Free Condition ◽  
Metal Free ◽  
Novel Method

This protocol provides a novel method for the synthesis of (Z)-tetrahydrothiophene derivatives through the formation of C–S bonds under transition-metal-free condition using thiyl radical intramolecular cycloaddition cascade strategy.

Synthesis of 1H-1,3-benzimidazoles, benzothiazoles and 3H-imidazo[4,5-c]pyridine using DMF in the presence of HMDS as a reagent under the transition-metal-free condition

2018 ◽  
Vol 72 (12) ◽  
pp. 2973-2978 ◽  
Author(s):  
Hamid Mostafavi ◽  
Mohammad Reza Islami ◽  
Ehsan Ghonchepour ◽  
Ahmad Momeni Tikdari
Keyword(s):  
Transition Metal ◽  
Free Condition ◽  
Metal Free

Oxidative Cross‐Coupling of Alcohols and Amines Catalyzed by TEMPO under Transition‐Metal‐Free Condition

2020 ◽  
Vol 5 (21) ◽  
pp. 6285-6293
Author(s):  
Revathi Chandrasekaran ◽  
Elgin Carlose ◽  
Ajun E. Muthu ◽  
Athira Suresh ◽  
Tamilselvi Chinnusamy
Keyword(s):  
Transition Metal ◽  
Cross Coupling ◽  
Free Condition ◽  
Metal Free

Carbazole and Triarylpyrrole Synthesis from Anilines and Cyclohexanones or Acetophenones under Transition-Metal-Free Condition

2017 ◽  
Vol 82 (11) ◽  
pp. 5743-5750 ◽  
Author(s):  
Jun Wu ◽  
Xiangui Chen ◽  
Yanjun Xie ◽  
Yanjun Guo ◽  
Qian Zhang ◽  
...  
Keyword(s):  
Transition Metal ◽  
Free Condition ◽  
Metal Free

Transition-metal-free catalytic hydroboration reduction of amides to amines

2020 ◽  
Vol 7 (21) ◽  
pp. 3515-3520
Author(s):  
Wubing Yao ◽  
Jiali Wang ◽  
Aiguo Zhong ◽  
Shiliang Wang ◽  
Yinlin Shao
Keyword(s):  
Transition Metal ◽  
Selective Catalytic Reduction ◽  
Catalytic Reduction ◽  
Value Added ◽  
Metal Free

The selective catalytic reduction of amides to value-added amine products is a desirable but challenging transformation.

Deaminative carbonylative thioesterification of activated alkylamines with thiophenols under transition-metal-free conditions

2021 ◽  
Author(s):  
Fengqian Zhao ◽  
Xiao-Feng Wu
Keyword(s):  
Free Radical ◽  
Transition Metal ◽  
Metal Free

A transition-metal-free radical carbonylation of activated alkylamines with thiophenols has been successfully developed. Various thioesters were selectively produced with moderate to good yields.

Regioselective C3-H Trifluoromethylation of 2H-Indazole Under Transition-Metal-Free Photoredox Catalysis

2019 ◽  
Author(s):  
Arumugavel Murugan ◽  
Venkata Nagarjuna Babu ◽  
Nagaraj Sabarinathan ◽  
Sharada Duddu. S
Keyword(s):  
Transition Metal ◽  
Visible Light ◽  
Practical Approach ◽  
Hypervalent Iodine ◽  
Radical Mechanism ◽  
Photoredox Catalysis ◽  
Metal Free

Here we report a visible-light-promoted metal-free regioselective C3-H trifluoromehtylation reaction that proceeds via radical mechanism and which supported by control experiments. The combination of photoredox catalysis and hypervalent iodine reagent provides a practical approach for the present trifluoromethylation reaction and synthesis of a library of trifluoromethylated indazoles.

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