scholarly journals A label-free microfluidic chip for the highly selective isolation of single and cluster CTCs from breast cancer patients

2021 ◽  
Vol 14 (1) ◽  
pp. 100959
Author(s):  
Xiaofen Zhang ◽  
Xu Lu ◽  
Wanlei Gao ◽  
Yanmin Wang ◽  
Chunping Jia ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Microfluidic Chip ◽  
Label Free ◽  
Selective Isolation ◽  
Breast Cancer Patients

Rapid isolation of circulating cancer associated fibroblasts by acoustic microstreaming for assessing metastatic propensity of breast cancer patients

Lab on a Chip ◽  
2021 ◽  
Author(s):  
Ruoyu Jiang ◽  
Sudhanshu Agrawal ◽  
Mohammad Aghaamoo ◽  
Ritesh Parajuli ◽  
Anshu Agrawal ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
High Throughput ◽  
Capture Efficiency ◽  
Cancer Associated Fibroblasts ◽  
Label Free ◽  
Breast Cancer Patients ◽  
Rapid Isolation ◽  
Functional Integrity ◽  
Circulating Cells

We demonstrate a label free and high-throughput microbubble-based acoustic microstreaming technique to isolate rare circulating cells from cancer patients with a capture efficiency of 94% while preserving cell functional integrity within 8 minutes.

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