scholarly journals Long noncoding RNA UCA1 promotes glutamine-driven anaplerosis of bladder cancer by interacting with hnRNP I/L to upregulate GPT2 expression

2022 ◽  
Vol 17 ◽  
pp. 101340
Author(s):  
Hua Zhao ◽  
Wenjing Wu ◽  
Xu Li ◽  
Wei Chen
Keyword(s):  
Bladder Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna

Long noncoding RNA MAGI2-AS3 regulates CCDC19 expression by sponging miR-15b-5p and suppresses bladder cancer progression

2018 ◽  
Vol 507 (1-4) ◽  
pp. 231-235 ◽  
Author(s):  
Feng Wang ◽  
Yanwen Zu ◽  
Shibin Zhu ◽  
Yu Yang ◽  
Weiping Huang ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Progression ◽  
Long Noncoding Rna ◽  
Noncoding Rna

scholarly journals An epithelial–mesenchymal transition-related long noncoding RNA signature correlates with the prognosis and progression in patients with bladder cancer

2021 ◽  
Vol 41 (1) ◽  
Author(s):  
Hang Tong ◽  
Tinghao Li ◽  
Shun Gao ◽  
Hubin Yin ◽  
Honghao Cao ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Epithelial Mesenchymal Transition ◽  
Enrichment Analysis ◽  
Functional Enrichment Analysis ◽  
Risk Groups ◽  
Functional Enrichment ◽  
Diagnostic Efficacy ◽  
Mesenchymal Transition

Abstract Bladder cancer is a common malignant tumour worldwide. Epithelial–mesenchymal transition (EMT)-related biomarkers can be used for early diagnosis and prognosis of cancer patients. To explore, accurate prediction models are essential to the diagnosis and treatment for bladder cancer. In the present study, an EMT-related long noncoding RNA (lncRNA) model was developed to predict the prognosis of patients with bladder cancer. Firstly, the EMT-related lncRNAs were identified by Pearson correlation analysis, and a prognostic EMT-related lncRNA signature was constructed through univariate and multivariate Cox regression analyses. Then, the diagnostic efficacy and the clinically predictive capacity of the signature were assessed. Finally, Gene set enrichment analysis (GSEA) and functional enrichment analysis were carried out with bioinformatics. An EMT-related lncRNA signature consisting of TTC28-AS1, LINC02446, AL662844.4, AC105942.1, AL049840.3, SNHG26, USP30-AS1, PSMB8-AS1, AL031775.1, AC073534.1, U62317.2, C5orf56, AJ271736.1, and AL139385.1 was constructed. The diagnostic efficacy of the signature was evaluated by the time-dependent receiver-operating characteristic (ROC) curves, in which all the values of the area under the ROC (AUC) were more than 0.73. A nomogram established by integrating clinical variables and the risk score confirmed that the signature had a good clinically predict capacity. GSEA analysis revealed that some cancer-related and EMT-related pathways were enriched in high-risk groups, while immune-related pathways were enriched in low-risk groups. Functional enrichment analysis showed that EMT was associated with abundant GO terms or signaling pathways. In short, our research showed that the 14 EMT-related lncRNA signature may predict the prognosis and progression of patients with bladder cancer.

scholarly journals Long noncoding RNA MAFG-AS1 facilitates bladder cancer tumorigenesis via regulation of miR-143-3p/SERPINE1 axis

2020 ◽  
Vol 9 (11) ◽  
pp. 7214-7226
Author(s):  
Xi Sun ◽  
Yi Cai ◽  
Xiheng Hu ◽  
Miao Mo ◽  
Cheng Zhao ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna

Long noncoding RNA DANCR facilitates metastasis and proliferation in bladder cancer cells by activating IL-11-STAT3 signaling

2019 ◽  
Vol 18 (1) ◽  
pp. e1626
Author(s):  
C. Xu ◽  
C. Ziyue ◽  
X. Ruihui ◽  
H. Ming ◽  
Z. Jingtong ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Cancer Cells ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Stat3 Signaling ◽  
Bladder Cancer Cells

scholarly journals Long noncoding RNA AC114812.8 promotes the progression of bladder cancer through miR-371b-5p/FUT4 axis

2020 ◽  
Vol 121 ◽  
pp. 109605 ◽  
Author(s):  
Weijian Li ◽  
Youjian Li ◽  
Wenliang Ma ◽  
Jun Zhou ◽  
Zhongxu Sun ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna

scholarly journals Long noncoding RNA DLX6-AS1 promotes cell growth and invasiveness in bladder cancer via modulating the miR-223-HSP90B1 axis

Cell Cycle ◽  
2019 ◽  
Vol 18 (23) ◽  
pp. 3288-3299 ◽  
Author(s):  
Chen Fang ◽  
Le Xu ◽  
Wei He ◽  
Jun Dai ◽  
Fukang Sun
Keyword(s):  
Bladder Cancer ◽  
Cell Growth ◽  
Long Noncoding Rna ◽  
Noncoding Rna

scholarly journals Long noncoding RNA expression signatures of bladder cancer revealed by microarray

2014 ◽  
Vol 7 (4) ◽  
pp. 1197-1202 ◽  
Author(s):  
YI-PING ZHU ◽  
XIAO-JIE BIAN ◽  
DING-WEI YE ◽  
XU-DONG YAO ◽  
SHI-LIN ZHANG ◽  
...  
Keyword(s):  
Bladder Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Rna Expression

Knockdown of long noncoding RNA FGFR3- AS1 induces cell proliferation inhibition, apoptosis and motility reduction in bladder cancer

2018 ◽  
Vol 21 (2) ◽  
pp. 277-285 ◽  
Author(s):  
Xinhui Liao ◽  
Jieqing Chen ◽  
Yuchen Liu ◽  
Anbang He ◽  
Jianting Wu ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Bladder Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Proliferation Inhibition ◽  
Cell Proliferation Inhibition
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