Impact of Human Leukocyte Antigen-DR Mismatch Status on Kidney Graft Survival in a Predominantly African-American Population Under the Newer Immunosuppressive Era

2011 ◽  
Vol 43 (5) ◽  
pp. 1544-1550 ◽  
Author(s):  
I. Karabicak ◽  
A. Adekile ◽  
D.A. Distant ◽  
D. O'Shaunessy ◽  
S. Lewis ◽  
...  
Keyword(s):  
African American ◽  
Human Leukocyte Antigen ◽  
Graft Survival ◽  
Human Leukocyte ◽  
Kidney Graft ◽  
American Population ◽  
Leukocyte Antigen ◽  
African American Population

scholarly journals PIRCHE-II: an algorithm to predict indirectly recognizable HLA epitopes in solid organ transplantation

2019 ◽  
Vol 72 (1-2) ◽  
pp. 119-129 ◽  
Author(s):  
Kirsten Geneugelijk ◽  
Eric Spierings
Keyword(s):  
Human Leukocyte Antigen ◽  
Organ Transplantation ◽  
Graft Survival ◽  
Solid Organ Transplantation ◽  
Human Leukocyte ◽  
Solid Organ ◽  
Hla Alleles ◽  
Leukocyte Antigen ◽  
Hla System ◽  
Hla Mismatches

AbstractHuman leukocyte antigen (HLA) mismatches between donors and recipients may lead to alloreactivity after solid organ transplantation. Over the last few decades, our knowledge of the complexity of the HLA system has dramatically increased, as numerous new HLA alleles have been identified. As a result, the likelihood of alloreactive responses towards HLA mismatches after solid organ transplantation cannot easily be assessed. Algorithms are promising solutions to estimate the risk for alloreactivity after solid organ transplantation. In this review, we show that the recently developed PIRCHE-II (Predicted Indirectly ReCognizable HLA Epitopes) algorithm can be used to minimize alloreactivity towards HLA mismatches. Together with the use of other algorithms and simulation approaches, the PIRCHE-II algorithm aims for a better estimated alloreactive risk for individual patients and eventually an improved graft survival after solid organ transplantation.

Impact of human leukocyte antigen (HLA) matching on graft survival after lung transplantation

2002 ◽  
Vol 21 (1) ◽  
pp. 169-170
Author(s):  
P.S Neuhauser ◽  
A Kocher ◽  
P Jaksch ◽  
T Wekerle ◽  
W Klepetko ◽  
...  
Keyword(s):  
Lung Transplantation ◽  
Human Leukocyte Antigen ◽  
Graft Survival ◽  
Human Leukocyte ◽  
Hla Matching ◽  
Leukocyte Antigen

Impact of Pretransplant Human Leukocyte Antigen-C and -DP Antibodies on Kidney Graft Outcome

2011 ◽  
Vol 43 (9) ◽  
pp. 3412-3414 ◽  
Author(s):  
M. Gilbert ◽  
S. Paul ◽  
G. Perrat ◽  
C. Giannoli ◽  
C. Pouteil Noble ◽  
...  
Keyword(s):  
Human Leukocyte Antigen ◽  
Human Leukocyte ◽  
Kidney Graft ◽  
Leukocyte Antigen ◽  
Graft Outcome
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