Mannose-Binding Lectin 2 and Ficolin-2 Gene Polymorphisms Influence the Susceptibility to Bloodstream Infections in Kidney Transplant Recipients

2013 ◽  
Vol 45 (9) ◽  
pp. 3289-3292 ◽  
Author(s):  
Q.-Q. Wan ◽  
Q.-F. Ye ◽  
J.-D. Zhou
Keyword(s):  
Kidney Transplant ◽  
Gene Polymorphisms ◽  
Bloodstream Infections ◽  
Mannose Binding Lectin ◽  
Transplant Recipients ◽  
Kidney Transplant Recipients ◽  
Mannose Binding ◽  
Binding Lectin

The Clinical Relevance Of Mannose-Binding Lectin (MBL) In Long Term Survival Of Lung Transplant Recipients

2010 ◽  
Author(s):  
Johanna M. Kwakkel-van Erp ◽  
Annelieke W. Paantjens ◽  
Diana A. van Kessel ◽  
Jules M.M. van den Bosch ◽  
Jan C. Grutters ◽  
...  
Keyword(s):  
Clinical Relevance ◽  
Lung Transplant ◽  
Mannose Binding Lectin ◽  
Transplant Recipients ◽  
Term Survival ◽  
Long Term Survival ◽  
Mannose Binding ◽  
Lung Transplant Recipients ◽  
Binding Lectin

Lack of association between Mannose Binding Lectin-2 gene polymorphisms and periodontitis: A meta-analysis

Meta Gene ◽  
2020 ◽  
Vol 26 ◽  
pp. 100757
Author(s):  
Felipe Rodolfo Pereira da Silva ◽  
Alessandro Luiz Araújo Bentes Leal ◽  
Luigi Nibali ◽  
Jae Il Shin ◽  
Marcelo Diniz Carvalho ◽  
...  
Keyword(s):  
Gene Polymorphisms ◽  
Meta Analysis ◽  
Mannose Binding Lectin ◽  
Mannose Binding ◽  
Binding Lectin

Mannose-binding Lectin MBL2 Gene Polymorphisms and Outcome of Hepatitis C Virus-infected Patients

2008 ◽  
Vol 28 (5) ◽  
pp. 495-500 ◽  
Author(s):  
Eirini Koutsounaki ◽  
George N. Goulielmos ◽  
Mary Koulentaki ◽  
Christianna Choulaki ◽  
Elias Kouroumalis ◽  
...  
Keyword(s):  
Hepatitis C Virus ◽  
Hepatitis C ◽  
Gene Polymorphisms ◽  
Mannose Binding Lectin ◽  
Mbl2 Gene ◽  
Mannose Binding ◽  
Binding Lectin

Mannose binding lectin 2 gene polymorphisms in patients after renal transplantation with acute graft rejection

2019 ◽  
Vol 54 ◽  
pp. 29-37 ◽  
Author(s):  
Michał Czerewaty ◽  
Maciej Tarnowski ◽  
Krzysztof Safranow ◽  
Leszek Domanski ◽  
Andrzej Pawlik
Keyword(s):  
Renal Transplantation ◽  
Graft Rejection ◽  
Gene Polymorphisms ◽  
Mannose Binding Lectin ◽  
Acute Graft Rejection ◽  
Mannose Binding ◽  
Binding Lectin ◽  
Acute Graft

scholarly journals Association between Mannose-Binding Lectin Gene Polymorphisms and Susceptibility to Severe Acute Respiratory Syndrome Coronavirus Infection

2005 ◽  
Vol 192 (8) ◽  
pp. 1355-1361 ◽  
Author(s):  
Hongxing Zhang ◽  
Gangqiao Zhou ◽  
Lianteng Zhi ◽  
Hao Yang ◽  
Yun Zhai ◽  
...  
Keyword(s):  
Severe Acute Respiratory Syndrome ◽  
Gene Polymorphisms ◽  
Direct Sequencing ◽  
Population Attributable Fraction ◽  
Mannose Binding Lectin ◽  
Promoter Polymorphisms ◽  
Homogeneous Population ◽  
Control Subjects ◽  
Mannose Binding ◽  
Binding Lectin

Abstract BackgroundGenetic determinants of susceptibility to severe acute respiratory syndrome coronavirus (SARS-CoV) infection remain unknown. We assessed whether mannose-binding lectin (MBL) gene polymorphisms were associated with susceptibility to SARS-CoV infection or disease severity in an ethnically homogeneous population born in northern China MethodsThe frequencies of 1 mutation in codon 54 and 3 promoter polymorphisms at nt −550, −221, and 4 were ascertained in 352 patients with SARS and 392 control subjects, by means of polymerase chain reaction direct sequencing ResultsOf 352 patients with SARS and 392 control subjects, 120 (34.4%) and 91 (23.2%) were carriers of the codon 54 variant, respectively (odds ratio [OR], 1.73 [95% confidence interval {CI}, 1.25–2.39]; P=.00086). A total of 123 (36.0%) of 352 patients with SARS and 100 (25.5%) of 392 control subjects had haplotype pairs associated with medium or low expression of MBL (OR, 1.67 [95% CI, 1.21–2.29]; P=.00187). The population-attributable fraction of patients with SARS that was associated with having the codon 54 variant was 20.1% (95% CI, 7.9%–32.3%) Conclusions MBL gene polymorphisms were significantly associated with susceptibility to SARS-CoV infection; this might be explained by the reduced expression of functional MBL secondary to having the codon 54 variant

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