hiv positive mothers
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2104 ◽  
Vol 15 (2) ◽  
pp. 14-22 ◽  
Author(s):  
Lydia Kapiriri ◽  
Wangari Tharao ◽  
Marvelous Muchenje ◽  
Khatundi Masinde ◽  
Sandi Siegel ◽  
...  

PLoS ONE ◽  
2022 ◽  
Vol 17 (1) ◽  
pp. e0262518
Author(s):  
Aurelie Kennedy Nelson ◽  
Tali Cassidy ◽  
Laura Trivino Duran ◽  
Vivian Cox ◽  
Catherine J. Wedderburn ◽  
...  

Background Despite the reduction of HIV mother-to-child transmission, there are concerns regarding transmission rate in the breastfeeding period. We describe the routine uptake of 6 or 10 (6/10) weeks, 9 months and 18 months testing, with and without tracing, in a cohort of infants who received HIV PCR testing at birth (birth PCR) (with and without point of care (POC) testing) in a peri-urban primary health care setting in Khayelitsha, South Africa. Methods In this cohort study conducted between November 2014 and February 2018, HIV-positive mothers and their HIV-exposed babies were recruited at birth and all babies were tested with birth PCR. Results of routine 6/10 weeks PCR, 9 months and 18 months testing were followed up by a patient tracer. We compared testing at 6/10 weeks with a subgroup from historical cohort who was not tested with birth PCR. Results We found that the uptake of 6/10 weeks testing was 77%, compared to 82% with tracing. When including all infants in the cascade and comparing to a historical cohort without birth testing, we found that infants who tested a birth were 22% more likely to have a 6/10 weeks test compared to those not tested at birth. There was no significant difference between the uptake of 6/10 weeks testing after birth PCR POC versus birth PCR testing without POC. Uptake of 9 months and 18 months testing was 39% and 24% respectively. With intense tracing efforts, uptake increased to 45% and 34% respectively. Conclusion Uptake of HIV testing for HIV-exposed uninfected infants in the first 18 months of life shows good completion of the 6/10 weeks PCR but suboptimal uptake of HIV testing at 9 months and 18 months, despite tracing efforts. Birth PCR testing did not negatively affect uptake of the 6/10 weeks HIV test compared to no birth PCR testing.


2021 ◽  
Vol 9 ◽  
Author(s):  
Mesfin Wudu Kassaw ◽  
Ayele Mamo Abebe ◽  
Biruk Beletew Abate ◽  
Mikiyas Amare Getu ◽  
Ayelign Mengesha Kassie

Background: Prevention of mother-to-child transmission of HIV program (PMTCT) is a comprehensive approach that aimed for the wellbeing of all HIV-infected women, to prevent new HIV infection among infants born to HIV-positive mothers, and providing management for HIV-positive women and infants. Nevertheless, there was considerably high attrition within the prevention of mother-to-child transmission programs that was merely because of loss to follow-up (LTFU) followed by mortality. In resource-limited countries, one-third of infected children die before 1 year, and more than half of them die before 2 years. The aim of this study was to assess the prevalence or incidence of mortality and LTFU among infants born from HIV-positive mothers in the Amhara regional state referral hospitals, Ethiopia.Methods: This study was conducted in five Amhara regional state referral hospitals' prevention of mother-to-child transmission departments. A simple random sampling technique with proportional allocation was used to assess the outcomes of 221 exposed infants. A retrospective cohort design was used in selecting the 221 exposed infants' document from the referral hospitals of the region, Amhara. The exposed infants' profiles were documented between January 1, 2014 and May 30, 2017.Results: This study described attritions (death and loss-to-follow-up) of exposed babies in PMTCT departments of Amhara regional state referral hospitals in Ethiopia. In this study, low LTFU with zero death was reported. Residence, immunization status of babies, and place of delivery were independent factors of LTFU.Conclusions: The cumulative incidence of mortality in this study was zero. This assured that the recommended option is substantial for the elimination of HIV-caused death in 2030 as per WHO plan. However, the cumulative incidence of LTFU was not zero.


2021 ◽  
Vol 21 (3) ◽  
Author(s):  
Daniel Opotamutale Ashipala ◽  
Getruida Shikukumwa ◽  
Medusalem Hangula Joel

Background: In sub-Saharan Africa, over 1,000 newborns are infected with HIV every day, despite available medical in- terventions. Mother-to-child transmission (MTCT) remains one of the primary sources of HIV infection in children and without interventions 40% of babies born from HIV-positive mothers would be infected with the virus. It is estimated that 300 000 children become infected with HIV worldwide, whilst 1.5 million children die when their mothers opt for other choices instead of breastfeeding. Objective: The purpose of the study was to assess and describe the knowledge, attitudes and practices of HIV-positive mothers regarding the benefits of exclusive breastfeeding at Rundu Intermediate Hospital, Kavango East Region in Namibia. Method: The study was a descriptive cross-sectional survey that used convenience sampling, as the researcher sought to use subjects available during the time of study to select 79 HIV positive mothers. Results: Participants in this study (94%; n=51) had good knowledge of the benefit of exclusive breastfeeding and that the benefits of breastfeeding outweigh the risk of HIV transmission from mother to child. The results confirmed that (77.2%; n=42) of the mothers opted to take ART with the babies until they stop breastfeeding. Conclusion: HIV positive mothers had good knowledge, attitudes and practices regarding the benefits of exclusive breast- feeding. A significant number of mothers were, however, not sure about breastfeeding exclusively for 6 months as they would stop if offered free formula milk for the baby. Support by the fathers and others in the community is vital. Keywords: Knowledge; HIV; breastfeeding; attitudes; practices; HIV-positive mothers; Namibia.


2021 ◽  
Vol 7 (9) ◽  
pp. 87727-87741
Author(s):  
José Henrique Rodrigues Machado ◽  
Tainá Goulart ◽  
Patrícia Lemes Silva ◽  
Evandro Barros Ribeiro ◽  
Joaquim Domingos Da Silva Neto

2021 ◽  
Vol 12 (2) ◽  
pp. 236
Author(s):  
Siti Waghisatul Astutik ◽  
Antono Suryoputro ◽  
Zahroh Shaluhiyah

AbstrakAIDS (Acquired Immunodeficiency Syndrome) merupakan kumpulan penyakit yang disebabkan oleh Virus HIV (Human Immunodeficiency Virus) yang menular dan mematikan. Berdasarkan data Kementrian Kesehatan pada tahun 2015 jumlah anak usia ≤ 4 tahun yang terinfeksi HIV sebanyak 795, meningkat pada tahun 2016 menjadi 903. Pencegahan Penularan HIV dari Ibu ke Anak dapat dilakukan melalui 4 (empat) prong/kegiatan, yaitu : 1) Pencegahan penularan HIV pada perempuan usia reproduksi, 2) Pencegahan kehamilan yang tidak direncanakan pada ibu HIV positif, 3) pencegahan penularan HIV dari ibu hamil HIV positif ke bayi yang dikandung, dan 4) pemberian dukungan psikologis, sosial dan perawatan kepada ibu HIV positif beserta anak dan keluarganya. Pencegahan Penularan HIV dari Ibu ke Anak (PPIA) atau Prevention Mother to Child Transmission (PMTCT) merupakan program pemerintah untuk mencegah penularan virus HIV/AIDS dari ibu ke bayi yang dikandungnya. Tujuan dari literature review ini adalah untuk mengetahui konsep, model atau teori yang efektif digunakan untuk mengeketahui gambaran indeks keluarga sehat di beberapa daerah Indonesia. Metode yang digunakan dengan cara melakukan pencarian beberapa studi yang diterbitkan melalui database Google Scholar, Science direct, dan Scopus. Studi yang dipilih diterbitkan dari tahun 2017-2021. Setelah dilakukan pencarian artikel dengan kata kunci tersebut maka total artikel yang di review dalam tinjauan literatur ini sebanyak 5 (lima) artikel. Faktor yang mempengaruhi pelaksanaan PMTCT adalah kelengkapan data, kualitas SDM, gender, serta dukungan keluarga. Kata Kunci: Evaluasi, Implementsi, PMTCT AbstractAIDS (Acquired Immunodeficiency Syndrome) is a collection of diseases caused by the infectious and deadly HIV Virus (Human Immunodeficiency Virus). Based on data from the Ministry of Health in 2015 the number of children aged ≤ 4 years infected with HIV as many as 795, increased in 2016 to 903. Prevention of HIV transmission from Mother to Child can be done through 4 (four) activities, namely: 1) Prevention of HIV transmission in women of reproductive age, 2) Prevention of unplanned pregnancy in HIV-positive mothers, 3) prevention of HIV transmission from HIV-positive pregnant women to conceived babies, and 4) providing psychological, social and care support to HIV-positive mothers and their children and families. Prevention of HIV Transmission from Mother to Child (PPIA) or Prevention Mother to Child Transmission (PMTCT) is a government program to prevent transmission of HIV/AIDS virus from mother to baby. The purpose of this literature review is to know the concept, model or theory that is effectively used to know the picture of healthy family index in some areas of Indonesia. The method is used by searching for several studies published through the Google Scholar, Science direct, and Scopus databases. Selected studies are published from 2017-2021. After searching for articles with these keywords, the total articles reviewed in this literature review as many as 5 (five) articles. Factors that affect the implementation of PMTCT are the completeness of data, the quality of human resources, gender, and family support.Keywords: Evaluation, Implementation, PMTCT 


2021 ◽  
Vol 4 (4) ◽  
pp. 15888-15897
Author(s):  
William Marllon Oliveira J. R. Dos Santos ◽  
Flaviane Magalhães Pimentel ◽  
Tatiane Santos Da Conceição ◽  
Camilla Portes De Moura ◽  
Fabiana Ferreira Koopmans

Author(s):  
Nathaniel D. Adewole ◽  
Adaora A. Okechukwu ◽  
Richard A. Offiong ◽  
Francis O. Adebayo ◽  
Dennis A. Isah ◽  
...  

Background: Anaemia in pregnancy and HIV infection are two common public health issues in sub-Saharan African with Nigeria bearing the greatest burden. The duo occurring together poses a higher risk of morbidity and mortality for both the foetus and the mother. We therefore conducted this study to determine the burden of anaemia and other haematological abnormalities among HIV positive pregnant mothers on antiretroviral therapy who attended antenatal clinical services in our health institution.Methods: A 10-year retrospective review from January 2010 to December 2019 of medical records of HIV positive mothers on highly anti-retroviral therapy in attendance for antenatal clinical services in our health institution was carried out for the above objectives. Information extracted were, age, HIV status, gestational age at delivery, type of antiretroviral drugs used, duration of use, haemoglobin level, platelet, and complete blood count at booking of the positive mothers.Results: Of a total of 330 HIV positive mothers seen during the review period, 82.7% were from rural communities, 88.8% were from middle socio-economic class, 80.0% were Christians, and 80.3% started their highly active antiretroviral therapy before their index pregnancy. Most, 51.5% and 42.7% were on zidovudine, lamivudine and nevirapine, and tenofovir with lamivudine and lopinavir boasted ritonavir combinations, while 94.2% were on 1st line antiretroviral medication. Their mean age, gestational age at delivery, and parity were 31.11±4.7 years, 38.57±3.1 weeks, and 2.0±1.6 respectively. The prevalence of anaemia, thrombocytopenia and leucopoenia were 36.1%, 4.8%, and 6.7% respectively while their mean CD4 cell count and viral loads at the point of booking were 543.63±283.7 cells/μl, and 2953.02±1619.9 copies/ml. The two maternal variables that showed significant relationship with haemoglobin concentration of <10 gm/dl was mother’s level of education x2=6.29, p=0.043, and her socio=economic class, x2=10.162, p=0.006.Conclusions: There is high burden of anaemia among HIV positive mothers on antiretroviral therapy in our environment. The prevalence of thrombocytopenia and leucopoenia was much lower. The burden of maternal anaemia was associated with maternal level of education and her socio-economic class.


2021 ◽  
Author(s):  
Ndidiamaka N. Amutah-Onukagha ◽  
Kafuli Agbemenu ◽  
Julie Cederbaum ◽  
Faith Fletcher ◽  
Winston Abara

Abstract Background: Daughters of HIV positive women are often exposed to similar factors that placed their mothers at risk of HIV. Compared to women of other racial/ethnic groups, African American women have disproportionately higher rates of HIV/AIDS. This pilot study examines the relationship between African American HIV positive mothers and their daughters, and this relationship’s association with mother-daughter HIV risk communication and related domains.Methods: This mixed-method study employed quantitative surveys and qualitative interviews. All participants completed the quantitative survey while qualitative data were collected from a subset of participants. Results: Ninety-eight percent of respondents were African American, 73% had been HIV-infected for at least 10 years, and the mean age was 49.9 years. Among daughters, 85% reported feeling comfortable talking to their mothers about sex.Discussion: Results underscore the need to strengthen the mother-daughter communication around these topics in ways that may positively influence the sexual behaviors of the daughter.


2021 ◽  
Vol 16 (1) ◽  
Author(s):  
Betty Mogesi Samburu ◽  
Judith Kimiywe ◽  
Sera Lewise Young ◽  
Frederick Murunga Wekesah ◽  
Milka Njeri Wanjohi ◽  
...  

Abstract Background Although recent policies have sought to increase the rates of exclusive breastfeeding (EBF) and continued breastfeeding for HIV exposed infants, few programs have considered the multiple social and cultural barriers to the practice. Therefore, to generate evidence for exclusive and continued breastfeeding policies in Kenya, we examined community perspectives on the facilitators and barriers in adherence to EBF for the HIV positive mothers. Methods Qualitative research was conducted in Koibatek, a sub-County in Baringo County Kenya, in August 2014 among 205 respondents. A total of 14 focus group discussions (n = 177), 14 In-depth Interviews and 16 key informant interviews were conducted. Transcribed data was analyzed thematically. NVivo version 10.0 computer qualitative software program was used to manage and facilitate the analysis. Results Facilitators to exclusive breastfeeding were perceived to include counselling at the health facility, desire to have a healthy baby, use of antiretroviral drugs and health benefits associated with breastmilk. Barriers to EBF included poor dissemination of policies, knowledge gap, misinterpretation of EBF, inadequate counselling, attitude of mother and health workers due to fear of vertical HIV transmission, stigma related to misconception and misinformation that EBF is only compulsory for HIV positive mothers, stigma related to HIV and disclosure, social pressure, lack of male involvement, cultural practices and traditions, employment, food insecurity. Conclusions There are multiple facilitators and barriers of optimal breastfeeding that needs a holistic approach to interventions aimed at achieving elimination of mother to child transmission. Extension of infant feeding support in the context of HIV to the community while building on existing interventions such as the Baby Friendly Community Initiative is key to providing confidential support services for the additional needs faced by HIV positive mothers.


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