scholarly journals Inhibition of T Helper Cell Differentiation by Tacrolimus or Sirolimus Results in Reduced B-Cell Activation: Effects on T Follicular Helper Cells

2019 ◽  
Vol 51 (10) ◽  
pp. 3463-3473 ◽  
Author(s):  
Rens Kraaijeveld ◽  
Yi Li ◽  
Lin Yan ◽  
Kitty de Leur ◽  
Marjolein Dieterich ◽  
...  
Keyword(s):  
Cell Differentiation ◽  
B Cell ◽  
Cell Activation ◽  
T Helper Cell ◽  
Helper Cell ◽  
B Cell Activation ◽  
T Helper ◽  
T Follicular Helper Cells ◽  
Helper Cells ◽  
Follicular Helper

scholarly journals Dendritic Cell-Independent B Cell Activation During Acute Virus Infection: A Role for Early CCR7-Driven B-T Helper Cell Collaboration

2007 ◽  
Vol 178 (3) ◽  
pp. 1468-1476 ◽  
Author(s):  
Elke Scandella ◽  
Katja Fink ◽  
Tobias Junt ◽  
Beatrice M. Senn ◽  
Evelyn Lattmann ◽  
...  
Keyword(s):  
Dendritic Cell ◽  
Virus Infection ◽  
B Cell ◽  
Cell Activation ◽  
T Helper Cell ◽  
Helper Cell ◽  
B Cell Activation ◽  
T Helper

T helper cell‐dependent B cell activation

1991 ◽  
Vol 5 (13) ◽  
pp. 2770-2776 ◽  
Author(s):  
Randolph J. Noelle ◽  
E. Charles Snow
Keyword(s):  
B Cell ◽  
Cell Activation ◽  
T Helper Cell ◽  
Helper Cell ◽  
B Cell Activation ◽  
T Helper

Mechanism of B Cell Activation by Monoclonal T Helper Cell Populations

1982 ◽  
pp. 385-395 ◽  
Author(s):  
Richard J. Hodes ◽  
Yoshihiro Asano ◽  
Minoru Shigeta ◽  
Karen S. Hathcock ◽  
Masao Kimoto ◽  
...  
Keyword(s):  
B Cell ◽  
Cell Activation ◽  
T Helper Cell ◽  
Helper Cell ◽  
Cell Populations ◽  
B Cell Activation ◽  
T Helper

scholarly journals A Rapid-Response Humoral Vaccine Platform Exploiting Pre-Existing Non-Cognate Populations of Anti-Vaccine or Anti-Viral CD4+ T Helper Cells to Confirm B Cell Activation

PLoS ONE ◽  
2016 ◽  
Vol 11 (11) ◽  
pp. e0166383 ◽  
Author(s):  
Thomas Hills ◽  
Phillip G. Jakeman ◽  
Robert C. Carlisle ◽  
Paul Klenerman ◽  
Leonard W. Seymour ◽  
...  
Keyword(s):  
B Cell ◽  
T Helper Cells ◽  
Cell Activation ◽  
Rapid Response ◽  
B Cell Activation ◽  
T Helper ◽  
Vaccine Platform ◽  
Helper Cells

T Helper Cell Activation in B-Cell Lymphomas

2002 ◽  
Vol 20 (12) ◽  
pp. 2904-2905 ◽  
Author(s):  
H. Bosshart ◽  
Stephen M. Ansell ◽  
Diane F. Jelinek ◽  
Peter J. Wettstein ◽  
Thomas E. Witzig
Keyword(s):  
B Cell ◽  
Cell Activation ◽  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
B Cell Lymphomas

scholarly journals Differentiation, functions, and roles of T follicular regulatory cells in autoimmune diseases

2021 ◽  
Vol 41 (1) ◽  
Author(s):  
He Hao ◽  
Shingo Nakayamada ◽  
Yoshiya Tanaka
Keyword(s):  
Cell Differentiation ◽  
Autoimmune Diseases ◽  
B Cell ◽  
Cell Activation ◽  
B Cell Differentiation ◽  
B Cell Activation ◽  
Regulatory Cells ◽  
Autoantibody Production ◽  
Follicular Helper ◽  
Autoantibody Response

AbstractT follicular helper cells participate in stimulating germinal center (GC) formation and supporting B cell differentiation and autoantibody production. However, T follicular regulatory (Tfr) cells suppress B cell activation. Since changes in the number and functions of Tfr cells lead to dysregulated GC reaction and autoantibody response, targeting Tfr cells may benefit the treatment of autoimmune diseases. Differentiation of Tfr cells is a multistage and multifactorial process with various positive and negative regulators. Therefore, understanding the signals regulating Tfr cell generation is crucial for the development of targeted therapies. In this review, we discuss recent studies that have elucidated the roles of Tfr cells in autoimmune diseases and investigated the modulators of Tfr cell differentiation. Additionally, potential immunotherapies targeting Tfr cells are highlighted.

scholarly journals Distinct T helper cell dependence of memory B-cell proliferation versus plasma cell differentiation

Immunology ◽  
2017 ◽  
Vol 150 (3) ◽  
pp. 329-342 ◽  
Author(s):  
Franziska Zabel ◽  
Antonia Fettelschoss ◽  
Monique Vogel ◽  
Pål Johansen ◽  
Thomas M. Kündig ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Cell Differentiation ◽  
B Cell ◽  
Plasma Cell ◽  
T Helper Cell ◽  
Helper Cell ◽  
T Helper ◽  
Memory B Cell ◽  
Plasma Cell Differentiation
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