scholarly journals Lung Ultrasound Severity Index: Development and Usefulness in Patients with Suspected SARS-Cov-2 Pneumonia. A Prospective Study

Author(s):  
Michele Domenico Spampinato ◽  
Andrea Sposato ◽  
Maria Teresa Migliano ◽  
Giovanni Gordini ◽  
Vincenzo Bua ◽  
...  
2019 ◽  
Vol 54 (9) ◽  
pp. 1479-1486 ◽  
Author(s):  
Anna Maria Musolino ◽  
Paolo Tomà ◽  
Maria Chiara Supino ◽  
Barbara Scialanga ◽  
Alessia Mesturino ◽  
...  

2020 ◽  
Author(s):  
Danilo Buonsenso ◽  
Annamaria Musolino ◽  
Valentina Ferro ◽  
Cristina De Rose ◽  
Rosa Morello ◽  
...  

ABSTRACTObjective and designOur prospective study is one of the largest prospective study assessing the role of detailed lung ultrasound features to discriminate the etiological diagnosis of Community acquired pneumonia (CAP) in children.MethodologyWe prospectively analysed patients aged from 1 month to 17 years admitted between March 2018 and April 2020 who were hospitalized for CAP. For all patients included in the study, history, clinical parameters, microbiological data, and lung ultrasound data were collected.Patients were stratified into three main groups (“bacterial”, “viral”, “atypical”) according to the presumed microbial aetiology and lung ultrasound findings evaluated according to the aetiological group.ResultsWe found that some ultrasound findings as size, number and distribution of consolidations, the position and motion of air bronchograms, pleural effusions and distribution of vertical artifacts significantly differ (p < 0.05) in children with bacterial, viral and atypical CAP. Conversely, clinical parameters and laboratory were not able to significantly distinguish between these groups. Chest x-ray, despite being still widely used, was the less useful tool in this discrimination.ConclusionOur study provides a detailed analysis of LUS features able to predict the etiology CAP in children. These findings may help the physicians to better manage a child with CAP and to offer personalized approach, from diagnosis to treatment and follow-up.


2020 ◽  
Vol 2 (4) ◽  
pp. 42-47
Author(s):  
Dr. MD Atik Ahmed ◽  
◽  
Dr. MD Toufik Ahemad ◽  
Dr. MD Mustak Ahmed ◽  
◽  
...  

Background: To assess the severity of acute pancreatitis (AP) using computed tomography (CT)severity index (CTSI) and modified CT severity index (MCTSI), to correlate with clinical outcomemeasures, and to assess concordance with severity grading, as per the revised Atlanta classification(RAC). Material and Methods: This is a prospective study, conducted from August 2019 to July2020, in the Department of Radiology, Al Ameen Medical College. A total of 70 patients referred fromthe Department of Medicine and Department of Surgery, presented with the chief complaint ofepigastric pain, nausea and vomiting and CECT abdomen were suggestive of acute pancreatitis wereincluded in this study. Assessment of severity of acute pancreatitis was done in all cases byBalthazar CTSI scoring and Mortele Modified CTSI scoring. Results: In the present study total 70cases of acute pancreatitis cases were included in the study. These patients underwent CT abdomenand pelvis, later images were reviewed by the radiologist. The maximum patients were in the agegroup of 21 to 40 years [n=33 (47.1%)]. Majority of the cases were categorized as mild pancreatitisaccording to Balthazar CTSI score. Majority of the cases were categorized as severe pancreatitisusing the Modified Mortele CTS score. Whereas, organ failure, moderate and severe category inmodified Mortele CTSI, mild, moderate, severe category in Balthazar CTSI. Conclusion: Inconclusion CECT was found to be an excellent imaging modality for diagnosis, establishing theextent of the disease process and in grading its severity.


2019 ◽  
Vol 50 (4) ◽  
pp. 364-369 ◽  
Author(s):  
Ji Yeon Ham ◽  
Kyung Eun Song

Abstract Despite widely used severity indices such as the pneumonia severity index (PSI) and CURB-65, a rapid, easy-to-detect biological marker is required for assessment of community-acquired pneumonia (CAP) severity. We aimed to investigate the ability of presepsin to differentiate between high- and low-risk patients, categorized according to PSI and CURB-65 scores. This prospective study was performed in an emergency department (ED) with 90 CAP patients. Whole blood presepsin levels were measured with a point-of-care test instrument. Using PSI and CURB-65 scores, we classified patients into outpatient (low-score group of PSI and CURB-65) and inpatient (high-score group of PSI and CURB-65) management groups. Presepsin levels were significantly higher in CAP patients with the high-score groups compared to the corresponding low-score groups. Presepsin correlated well with low- and high-score PSI (ROC AUC: presepsin, 0.726; PCT, 0.614; CRP, 0.544) and CURB-65 groups (ROC AUC: presepsin, 0.669; PCT, 0.645; CRP, 0.602). Presepsin is a valuable biomarker for assessing and classifying CAP severity.


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