scholarly journals Synthetic peptides coupled to the surface of liposomes effectively induce SARS coronavirus-specific cytotoxic T lymphocytes and viral clearance in HLA-A*0201 transgenic mice

Vaccine ◽  
2009 ◽  
Vol 27 (29) ◽  
pp. 3912-3920 ◽  
Author(s):  
Satoshi Ohno ◽  
Shunsuke Kohyama ◽  
Maiko Taneichi ◽  
Osamu Moriya ◽  
Hidenori Hayashi ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Transgenic Mice ◽  
Cytotoxic T Lymphocytes ◽  
Synthetic Peptides ◽  
Viral Clearance ◽  
Sars Coronavirus

scholarly journals Th1 but not Th0 cell help is efficient to induce cytotoxic T lymphocytes by immunization with short synthetic peptides

1999 ◽  
Vol 11 (12) ◽  
pp. 2025-2034 ◽  
Author(s):  
Ascensión López-Díaz de Cerio ◽  
Noelia Casares ◽  
Juan José Lasarte ◽  
Pablo Sarobe ◽  
Luis Alberto Pérez-Mediavilla ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes ◽  
Synthetic Peptides

scholarly journals Transgenic Mice Expressing Human HLA and CD8 Molecules Generate HLA-Restricted Measles Virus Cytotoxic T Lymphocytes of the Same Specificity as Humans with Natural Measles Virus Infection

Virology ◽  
2000 ◽  
Vol 275 (2) ◽  
pp. 286-293 ◽  
Author(s):  
Antoinette Tishon ◽  
Drake M. LaFace ◽  
Hanna Lewicki ◽  
Robert S. van Binnendijk ◽  
Albert Osterhaus ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Virus Infection ◽  
Transgenic Mice ◽  
Cytotoxic T Lymphocytes ◽  
Measles Virus

scholarly journals Use of synthetic peptides of influenza nucleoprotein to define epitopes recognized by class I-restricted cytotoxic T lymphocytes.

1987 ◽  
Vol 165 (6) ◽  
pp. 1508-1523 ◽  
Author(s):  
J Bastin ◽  
J Rothbard ◽  
J Davey ◽  
I Jones ◽  
A Townsend
Keyword(s):  
T Cells ◽  
T Lymphocytes ◽  
Infected Cell ◽  
Cytotoxic T Lymphocytes ◽  
Synthetic Peptides ◽  
Class Ii ◽  
Cytotoxicity Assay ◽  
Class I ◽  
Class I Mhc

The conserved epitopes of influenza nucleoprotein (NP) recognized by class I MHC-restricted CTL from CBA (H-2k) and C57BL/10 (H-2b) mice have been defined in vitro with synthetic peptides 50-63 and 365-379, respectively. Two Db-restricted clones were described that recognize different epitopes on peptide 365-379. Finally, the recognition of complete NP was shown to be approximately 200-fold less efficient than peptide in the cytotoxicity assay. These phenomena are closely related to results with class II-restricted T cells and they strengthen the hypothesis that influenza proteins are degraded in the infected cell before recognition by class I-restricted CTL.

Polymorphonuclear neutrophils pulsed with synthetic peptides efficiently activate memory cytotoxic T lymphocytes

1996 ◽  
Vol 60 (2) ◽  
pp. 207-213 ◽  
Author(s):  
Eva Reali ◽  
Remo Guerrini ◽  
Sabrina Moretti ◽  
Susanna Spisani ◽  
Francesco Lanza ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Cytotoxic T Lymphocytes ◽  
Synthetic Peptides ◽  
Polymorphonuclear Neutrophils ◽  
Memory Cytotoxic T Lymphocytes

HIV-1 gag-specific cytotoxic T lymphocytes defined with recombinant vaccinia virus and synthetic peptides

Nature ◽  
1988 ◽  
Vol 336 (6198) ◽  
pp. 484-487 ◽  
Author(s):  
Douglas F. Nixon ◽  
Alain R. M. Townsend ◽  
John G. Elvin ◽  
Charles R. Rizza ◽  
John Gallwey ◽  
...  
Keyword(s):  
T Lymphocytes ◽  
Vaccinia Virus ◽  
Cytotoxic T Lymphocytes ◽  
Synthetic Peptides ◽  
Recombinant Vaccinia Virus ◽  
Recombinant Vaccinia ◽  
Hiv 1
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