Vaccination with the recombinant chimeric antigen recNcMIC3-1-R induces a non-protective Th2-type immune response in the pregnant mouse model for N. caninum infection

Vaccine ◽  
2012 ◽  
Vol 30 (46) ◽  
pp. 6588-6594 ◽  
Author(s):  
Thierry Monney ◽  
Karim Debache ◽  
Denis Grandgirard ◽  
Stephen L. Leib ◽  
Andrew Hemphill
Keyword(s):  
Immune Response ◽  
Mouse Model ◽  
Pregnant Mouse ◽  
Caninum Infection

Characterization of an Outbred Pregnant Mouse Model of Neospora caninum Infection

2002 ◽  
Vol 88 (4) ◽  
pp. 691
Author(s):  
Helen E. Quinn ◽  
Catherine M. D. Miller ◽  
Cheryl Ryce ◽  
Peter A. Windsor ◽  
John T. Ellis
Keyword(s):  
Mouse Model ◽  
Neospora Caninum ◽  
Pregnant Mouse ◽  
Caninum Infection

CHARACTERIZATION OF AN OUTBRED PREGNANT MOUSE MODEL OF NEOSPORA CANINUM INFECTION

2002 ◽  
Vol 88 (4) ◽  
pp. 691-696 ◽  
Author(s):  
Helen E. Quinn ◽  
Catherine M. D. Miller ◽  
Cheryl Ryce ◽  
Peter A. Windsor ◽  
John T. Ellis
Keyword(s):  
Mouse Model ◽  
Neospora Caninum ◽  
Pregnant Mouse ◽  
Caninum Infection

scholarly journals Effects of Neospora caninum Infection at Mid-Gestation on Placenta in a Pregnant Mouse Model

2010 ◽  
Vol 96 (5) ◽  
pp. 1017-1020 ◽  
Author(s):  
I. C. López-Pérez ◽  
E. Collantes-Fernández ◽  
S. Rojo-Montejo ◽  
V. Navarro-Lozano ◽  
V. Risco-Castillo ◽  
...  
Keyword(s):  
Mouse Model ◽  
Neospora Caninum ◽  
Pregnant Mouse ◽  
Caninum Infection

scholarly journals Use of a Th1 Stimulator Adjuvant for Vaccination against Neospora caninum Infection in the Pregnant Mouse Model

Pathogens ◽  
2013 ◽  
Vol 2 (2) ◽  
pp. 193-208 ◽  
Author(s):  
Thierry Monney ◽  
Denis Grandgirard ◽  
Stephen Leib ◽  
Andrew Hemphill
Keyword(s):  
Mouse Model ◽  
Neospora Caninum ◽  
Pregnant Mouse ◽  
Caninum Infection

scholarly journals Polymorphonuclear Neutrophils Are Necessary for the Recruitment of CD8+ T Cells in the Liver in a Pregnant Mouse Model of Chlamydophila abortus (Chlamydia psittaci Serotype 1) Infection

2000 ◽  
Vol 68 (3) ◽  
pp. 1746-1751 ◽  
Author(s):  
Roberto Montes de Oca ◽  
Antonio J. Buendía ◽  
Laura Del Río ◽  
Joaquín Sánchez ◽  
Jesús Salinas ◽  
...  
Keyword(s):  
Immune Response ◽  
Mouse Model ◽  
Pregnant Mouse ◽  
Chlamydia Psittaci ◽  
Polymorphonuclear Neutrophils ◽  
Interleukin 4 ◽  
Specific Response ◽  
Chlamydophila Abortus ◽  
Serotype 1 ◽  
Leukocyte Populations

ABSTRACT The role of polymorphonuclear neutrophils (PMNs) in the development of the specific immune response against Chlamydophila abortus (Chlamydia psittaci serotype 1) infection was studied in a pregnant mouse model involving treatment with RB6-8C5 monoclonal antibody. PMN depletion significantly affected the immune response in the liver, in which the T-lymphocyte and F4/80+cell populations decreased, particularly the CD8+ T-cell population. A Th1-like response, characterized by high levels of gamma interferon without detectable levels of interleukin 4 (IL-4) in serum, was observed in both depleted and nondepleted mice, although an increased production of IL-10 was detected in the depleted group. Our results suggest that PMNs play a very important role in the recruitment of other leukocyte populations to the inflammatory foci but have little influence in the polarization of the immune specific response toward a Th1-like response.

scholarly journals Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Showed Cardioprotection Effect in a Myocardial Ischemia (MI) Mouse Model

Proceedings ◽  
2019 ◽  
Vol 22 (1) ◽  
pp. 72
Author(s):  
Lena Trifonov ◽  
Vadim Nudelman ◽  
Michael Zhenin ◽  
Guy Cohen ◽  
Krzysztof Jozwiak ◽  
...  
Keyword(s):  
Immune Response ◽  
Pattern Recognition ◽  
Myocardial Ischemia ◽  
Mouse Model ◽  
Innate Immune Response ◽  
Pattern Recognition Receptor ◽  
Innate Immune ◽  
Microbial Pathogens ◽  
Toll Like Receptors ◽  
Recognition Receptor

TLR4, a member of the toll-like receptors (TLRs) family, serves as a pattern recognition receptor in the innate immune response to different microbial pathogens. [...]

Beneficial Effects of Fingolimod on Social Interaction, CNS and Peripheral Immune Response in the BTBR Mouse Model of Autism

Neuroscience ◽  
2020 ◽  
Vol 435 ◽  
pp. 22-32
Author(s):  
Roberta De Simone ◽  
Alessia Butera ◽  
Monica Armida ◽  
Antonella Pezzola ◽  
Monica Boirivant ◽  
...  
Keyword(s):  
Immune Response ◽  
Social Interaction ◽  
Mouse Model ◽  
Beneficial Effects ◽  
Btbr Mouse ◽  
Peripheral Immune Response

Aggregate content influences the Th1/Th2 immune response to influenza vaccine: Evidence from a mouse model

2003 ◽  
Vol 72 (1) ◽  
pp. 138-142 ◽  
Author(s):  
Shawn Babiuk ◽  
Danuta M. Skowronski ◽  
Gaston De Serres ◽  
Kent HayGlass ◽  
Robert C. Brunham ◽  
...  
Keyword(s):  
Immune Response ◽  
Mouse Model ◽  
Influenza Vaccine ◽  
Aggregate Content ◽  
Th2 Immune Response
Sign in / Sign up

Export Citation Format

Share Document