Quantitative Systems Pharmacology Approach for Risk Assessment on Drug-Induced Proarrhythmic Effects with Physiologically Based Pharmacokinetic Model

2017 ◽  
Vol 88 ◽  
pp. 183
Author(s):  
Mikiko Nakamura ◽  
Fumiya Yoneyama ◽  
Akira Hirata ◽  
Kazuyuki Fujishima ◽  
Ryuta Saito
Keyword(s):  
Risk Assessment ◽  
Pharmacokinetic Model ◽  
Systems Pharmacology ◽  
Physiologically Based Pharmacokinetic Model ◽  
Drug Induced ◽  
Quantitative Systems Pharmacology ◽  
Physiologically Based Pharmacokinetic ◽  
Physiologically Based

Physiologically Based Pharmacokinetic Model Use in Risk Assessment—Why Being Published Is Not Enough

2011 ◽  
Vol 126 (1) ◽  
pp. 5-15 ◽  
Author(s):  
Eva D. McLanahan ◽  
Hisham A. El-Masri ◽  
Lisa M. Sweeney ◽  
Leonid Y. Kopylev ◽  
Harvey J. Clewell ◽  
...  
Keyword(s):  
Risk Assessment ◽  
Pharmacokinetic Model ◽  
Physiologically Based Pharmacokinetic Model ◽  
Physiologically Based Pharmacokinetic ◽  
Physiologically Based
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