Skull Base Juvenile Psammomatoid Ossifying Fibroma: Clinical Characteristics, Treatment, and Prognosis

Juvenile psammomatoid ossifying fibroma (JPOF) is a fibroosseous tumor that arises in the craniofacial bones in young people. This lesion usually originates in the jaw, orbit, and ethmoid complex but can also be associated with the skull base and calvaria. Diagnosis must be made based on observing typical radiological and histopathological features. Although JPOF is a rare pathological entity, neurosurgeons must consider this odontogenic lesion in the differential diagnosis of skull masses given the lesion’s aggressive behavior and locally invasive growth. Treatment must be gross-total resection. In the following article, the authors present a case of cranial JPOF and discuss various aspects of this entity.

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Juvenile psammomatoid ossifying fibroma in paranasal sinus and skull base

Acta Oto-Laryngologica ◽

10.1080/00016489.2016.1276302 ◽

2017 ◽

Vol 137 (7) ◽

pp. 743-749 ◽

Cited By ~ 7

Author(s):

Mingjie Wang ◽

Bing Zhou ◽

Shunjiu Cui ◽

Yunchuan Li

Keyword(s):

Skull Base ◽

Paranasal Sinus ◽

Ossifying Fibroma ◽

Psammomatoid Ossifying Fibroma

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Subacute cystic expansion of intracranial juvenile psammomatoid ossifying fibroma

Journal of Neurosurgery Pediatrics ◽

10.3171/2013.2.peds12253 ◽

2013 ◽

Vol 11 (6) ◽

pp. 687-691 ◽

Cited By ~ 8

Author(s):

Nathan C. Rowland ◽

Walter J. Jermakowicz ◽

Tarik Tihan ◽

Ivan H. El-Sayed ◽

Michael W. McDermott

Keyword(s):

Aggressive Behavior ◽

Skull Base ◽

Surgical Approach ◽

Neurological Deficit ◽

Ossifying Fibroma ◽

Distinct Population ◽

Focal Neurological Deficit ◽

Osseous Lesion ◽

Psammomatoid Ossifying Fibroma ◽

Active Processes

Juvenile psammomatoid ossifying fibroma (JPOF) is a benign fibro-osseous lesion typically associated with the jaw, paranasal region, or orbit. However, JPOF may also originate from the skull base and locally invade the cranium. In published reports, intracranial JPOFs constitute only a small percentage of cases, and therefore it is not known whether more aggressive behavior typifies this distinct population of JPOFs compared with those in other locations. Nevertheless, JPOF histopathology is characterized by a number of active processes, including cystic transformation, that may precipitate violation of skull base boundaries. In the following article, the authors present a case of skull base JPOF that underwent cystic expansion in a young girl, produced a focal neurological deficit, and was resolved using a staged surgical approach.

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Aggressive Neurocranial Juvenile Psammomatoid Ossifying Fibroma

10.1055/s-0040-1702716 ◽

2020 ◽

Author(s):

Cheyanne M. Silver ◽

Lucas P. Carlstrom ◽

Christopher S. Graffeo ◽

Avital Perry ◽

Garret W. Choby ◽

...

Keyword(s):

Ossifying Fibroma ◽

Psammomatoid Ossifying Fibroma

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The Microsurgical Relationships between Internal Carotid-Posterior Communicating Artery Aneurysms and the Skull Base

Journal of Neurological Surgery Part B Skull Base ◽

10.1055/s-0037-1615804 ◽

2017 ◽

Vol 79 (05) ◽

pp. 427-436 ◽

Cited By ~ 1

Author(s):

Noritaka Komune ◽

Ryosuke Tsuchimochi ◽

Yasutoshi Kai ◽

Kenichi Matsumoto ◽

Sei Haga ◽

...

Keyword(s):

Skull Base ◽

Clinical Characteristics ◽

Internal Carotid ◽

Posterior Communicating Artery ◽

Microsurgical Anatomy ◽

Anterior Clinoid Process ◽

Anterior Clinoidectomy ◽

Close Relationship ◽

Anatomical Relationship ◽

Formalin Fixed

Objective This study aimed to review the anatomical and clinical characteristics of internal carotid-posterior communicating artery (IC-PC) aneurysms, especially those located close to the skull base. Methods The microsurgical anatomy around the posterior communicating artery (PComA) was examined in a dry skull and five formalin-fixed human cadaveric heads. The clinical characteristics of 37 patients with 39 IC-PC aneurysms, who were treated microsurgically between April 2008 and July 2016, were retrospectively reviewed. Results The anterior clinoid process (ACP), as well as the anterior petroclinoidal dural fold (APF), which forms part of the oculomotor triangle, are closely related to the origin of the PComA. Among the 39 IC-PC aneurysms, anterior clinoidectomy was performed on 4 (10.3%) and a partial resection of the APF was performed on 2 (5.1%). Both of these aneurysms projected inferior to the tentorium, or at least part of the aneurysm's dome was inferior to the tentorium. Conclusion Proximally located IC-PC aneurysms have an especially close relationship with the ACP and APF. We should be familiar with the anatomical relationship between IC-PC aneurysms and the structures of the skull base to avoid hazardous complications.

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Endoscopic surgical treatment with nasal cavity approach for chondrosarcoma of paranasal sinus and the skull base

10.21203/rs.2.15283/v1 ◽

2019 ◽

Author(s):

Junxiao Gao ◽

Zhenchao Zhu ◽

Yudong Ye ◽

Qianhui Qiu ◽

Ming Fu

Keyword(s):

Skull Base ◽

Paranasal Sinus ◽

Endoscopic Surgery ◽

Clinical Characteristics ◽

Clinical Symptoms ◽

Residual Tumor ◽

Clinical Results ◽

Blurred Vision ◽

Normal Tissues ◽

Attachment Sites

Abstract Background Chondrosarcoma(ChSa) is a rare malignant tumor. But it’s necessary to discuss the clinical characteristics and treatments for ChSa of paranasal sinus and the skull base. Methods The clinical characteristics of ChSa of paranasal sinus and skull base in 10 patients (6 males and 4 females) from 2001 to 2017 were analyzed. They all underwent by endoscopic surgery . The patients’ age ranged from 18 to 47 years, with a median of 35 years. Clinical symptoms: stuffy, nose bleeding, runny, headache, diplopia, eye outreach limited, blurred vision and even blindness. Surgery methods：under nasal endoscopy, after the attachment sites of the tumors to normal tissues were confirmed, the tumors were peeled off along the clear boundary between the tumors and normal tissues, and the potential residual tumor tissues on bones were cleared by a drill. Results All patients were treated with endoscopic surgery，followed up postoperatively for 24 to 108 months, with a median of 36 months. 8 of 10 patients were no recurrence,2 were alive with tumor. Conclusion ChSa of paranasal sinus and skull base can be treated by nasal endoscopic surgery with good clinical results.

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A Case of Juvenile Psammomatoid Ossifying Fibroma in the Ethmoid Sinus

Nihon Bika Gakkai Kaishi (Japanese Journal of Rhinology) ◽

10.7248/jjrhi.59.6 ◽

2020 ◽

Vol 59 (1) ◽

pp. 6-12

Author(s):

Hiroyuki Morishita ◽

Masayoshi Kobayashi ◽

Kazuhiko Takeuchi

Keyword(s):

Ethmoid Sinus ◽

Ossifying Fibroma ◽

Psammomatoid Ossifying Fibroma

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Juvenile Psammomatoid Ossifying Fibroma of Fronto-Ethmoid Complex Mimicking Fibrous Dysplasia: Case Report

Nepalese Journal of Radiology ◽

10.3126/njr.v8i1.20454 ◽

2018 ◽

Vol 8 (1) ◽

pp. 33-36

Author(s):

Kapil Adhikari ◽

Ashok Raj Pant ◽

Sapana Koirala

Keyword(s):

Differential Diagnosis ◽

Case Report ◽

Fibrous Dysplasia ◽

Histopathological Examination ◽

Plain Radiograph ◽

Ossifying Fibroma ◽

Histopathological Findings ◽

Psammomatoid Ossifying Fibroma

Juvenile Psammomatoid Ossifying Fibromais a rare fibro-osseous tumor seen in children and adolescentand mostly arising from the cranio-facial bone.We report a case of 18-year-old boy who presented with diplopiaand progressive right fronto-orbital swelling. On plain radiograph and CT, it was diagnosed as fibrous dysplasiaand mucocele as differential diagnosis. The tumor was resected and histopathological examination showed psammomatoid features. Therefore, the diagnosis of Juvenile Psammomatoid Ossifying Fibroma must be based on both radiological and histopathological findings.

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