Subacute cystic expansion of intracranial juvenile psammomatoid ossifying fibroma

2013 ◽  
Vol 11 (6) ◽  
pp. 687-691 ◽  
Author(s):  
Nathan C. Rowland ◽  
Walter J. Jermakowicz ◽  
Tarik Tihan ◽  
Ivan H. El-Sayed ◽  
Michael W. McDermott
Keyword(s):  
Aggressive Behavior ◽  
Skull Base ◽  
Surgical Approach ◽  
Neurological Deficit ◽  
Ossifying Fibroma ◽  
Distinct Population ◽  
Focal Neurological Deficit ◽  
Osseous Lesion ◽  
Psammomatoid Ossifying Fibroma ◽  
Active Processes

Juvenile psammomatoid ossifying fibroma (JPOF) is a benign fibro-osseous lesion typically associated with the jaw, paranasal region, or orbit. However, JPOF may also originate from the skull base and locally invade the cranium. In published reports, intracranial JPOFs constitute only a small percentage of cases, and therefore it is not known whether more aggressive behavior typifies this distinct population of JPOFs compared with those in other locations. Nevertheless, JPOF histopathology is characterized by a number of active processes, including cystic transformation, that may precipitate violation of skull base boundaries. In the following article, the authors present a case of skull base JPOF that underwent cystic expansion in a young girl, produced a focal neurological deficit, and was resolved using a staged surgical approach.

scholarly journals Cranial juvenile psammomatoid ossifying fibroma: case report

2016 ◽  
Vol 17 (3) ◽  
pp. 318-323 ◽  
Author(s):  
Cristina Barrena López ◽  
Alicia Bollar Zabala ◽  
Enrique Úrculo Bareño
Keyword(s):  
Differential Diagnosis ◽  
Case Report ◽  
Young People ◽  
Aggressive Behavior ◽  
Skull Base ◽  
Ossifying Fibroma ◽  
Invasive Growth ◽  
Total Resection ◽  
Odontogenic Lesion ◽  
Psammomatoid Ossifying Fibroma

Juvenile psammomatoid ossifying fibroma (JPOF) is a fibroosseous tumor that arises in the craniofacial bones in young people. This lesion usually originates in the jaw, orbit, and ethmoid complex but can also be associated with the skull base and calvaria. Diagnosis must be made based on observing typical radiological and histopathological features. Although JPOF is a rare pathological entity, neurosurgeons must consider this odontogenic lesion in the differential diagnosis of skull masses given the lesion’s aggressive behavior and locally invasive growth. Treatment must be gross-total resection. In the following article, the authors present a case of cranial JPOF and discuss various aspects of this entity.

Skull Base Juvenile Psammomatoid Ossifying Fibroma: Clinical Characteristics, Treatment, and Prognosis

2019 ◽  
Vol 125 ◽  
pp. e843-e848 ◽  
Author(s):  
Ke Wang ◽  
Xiu-Jian Ma ◽  
Shu-Yu Hao ◽  
Jiang Du ◽  
Li-Wei Zhang ◽  
...  
Keyword(s):  
Skull Base ◽  
Clinical Characteristics ◽  
Ossifying Fibroma ◽  
Psammomatoid Ossifying Fibroma

A Case of Juvenile Psammomatoid Ossifying Fibroma on Skull Base

2018 ◽  
Vol 29 (5) ◽  
pp. e497-e499 ◽  
Author(s):  
Do-Youn Kim ◽  
Oh Hyeong Lee ◽  
Gyeong Cheol Choi ◽  
Jin Hee Cho
Keyword(s):  
Skull Base ◽  
Ossifying Fibroma ◽  
Psammomatoid Ossifying Fibroma

Fibrous dysplasia and ossifying fibroma of the paranasal sinuses

1998 ◽  
Vol 112 (10) ◽  
pp. 964-968 ◽  
Author(s):  
D. J. Commins ◽  
N. S. Tolley ◽  
C. A. Milford
Keyword(s):  
Fibrous Dysplasia ◽  
Surgical Approach ◽  
Paranasal Sinuses ◽  
Radical Surgery ◽  
Anterior Skull Base ◽  
Ossifying Fibroma ◽  
Clinical Classification ◽  
Osseous Lesion ◽  
Clinical Behaviour ◽  
Management Perspective

AbstractFibro-osseous lesions involving the paranasal sinuses, the mid-face and anterior skull base are uncommon. In addition, there appears to be no clear pathological or clinical classification that embraces the variety of lesions that exhibit such diverse pathological and clinical behaviour, yet may still be referred to as a fibro-osseous lesion. The diagnosis of fibrous dysplasia and ossifying fibroma is made on a combination of clinical, radiological and pathological criteria.This paper emphasizes the clinical and pathological differences between fibrous dysplasia and ossifying fibroma. The more aggressive clinical behaviour of the latter is highlighted and a more radical surgical approach i s recommended. In contradistinction, fibrous dysplasia can exhibit a more benign behaviour and radical surgery s i not always justified.A clinicopathological distinction between these two conditions is important from a management perspective despite the fact that they both may be encompassed under the ‘umbrella’ term fibro-osseous lesion.

scholarly journals Juvenile psammomatoid ossifying fibroma with skull base and orbital wall invasion: a rare case report

ENT Updates ◽  
2017 ◽  
Vol 7 (3) ◽  
pp. 157-160
Author(s):  
Özlem Ünsal ◽  
Pınar Soytaş ◽  
Fevziye Kabukçuoğlu ◽  
Berna Uslu Coşkun
Keyword(s):  
Case Report ◽  
Skull Base ◽  
Rare Case ◽  
Ossifying Fibroma ◽  
Orbital Wall ◽  
Rare Case Report ◽  
Psammomatoid Ossifying Fibroma ◽  
Wall Invasion

Juvenile psammomatoid ossifying fibroma in paranasal sinus and skull base

2017 ◽  
Vol 137 (7) ◽  
pp. 743-749 ◽  
Author(s):  
Mingjie Wang ◽  
Bing Zhou ◽  
Shunjiu Cui ◽  
Yunchuan Li
Keyword(s):  
Skull Base ◽  
Paranasal Sinus ◽  
Ossifying Fibroma ◽  
Psammomatoid Ossifying Fibroma

scholarly journals Juvenile psammomatoid ossifying fibroma of the parietal bone and review of calvarial presentations: illustrative case

2021 ◽  
Vol 2 (10) ◽  
Author(s):  
Robert T. Chung ◽  
Julio D. Montejo ◽  
Darcy A. Kerr ◽  
Jennifer Hong
Keyword(s):  
Molecular Mechanisms ◽  
Parietal Bone ◽  
Ossifying Fibroma ◽  
Illustrative Case ◽  
Osseous Lesion ◽  
Left Parietal Bone ◽  
Psammomatoid Ossifying Fibroma

BACKGROUND Juvenile psammomatoid ossifying fibroma (JPOF) is an uncommon benign fibro-osseous lesion that only rarely presents in the calvaria. OBSERVATIONS The authors reported a case of JPOF in the left parietal bone of a 20-year-old patient and reviewed the 27 other cases of JPOF occurring in the calvaria as reported in the literature. LESSONS JPOF rarely presents in the calvaria, and because diagnosis is a histopathologic one, clinicians should consider this entity when presented with a lytic, expansile mass on imaging. Little is known about the molecular mechanisms driving development of JPOF. MDM2 amplification may play a role, although this was not seen in the case presented herein.

Aggressive Neurocranial Juvenile Psammomatoid Ossifying Fibroma

2020 ◽  
Author(s):  
Cheyanne M. Silver ◽  
Lucas P. Carlstrom ◽  
Christopher S. Graffeo ◽  
Avital Perry ◽  
Garret W. Choby ◽  
...  
Keyword(s):  
Ossifying Fibroma ◽  
Psammomatoid Ossifying Fibroma

Hypoglycemic Hemiparesis Masquerading As Ischemic Stroke: When Guideline Fails

2020 ◽  
Vol 15 (4) ◽  
pp. 420-422
Author(s):  
Dhruvkumar M. Patel ◽  
Mukundkumar V. Patel ◽  
Jayanti K. Gurumukhani ◽  
Maitri M. Patel ◽  
Himal J. Mahadevia ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Thrombolytic Therapy ◽  
Neurological Deficit ◽  
Clinical Case ◽  
Complete Recovery ◽  
Acute Onset ◽  
Diabetic Patients ◽  
Focal Neurological Deficit ◽  
Random Blood Sugar ◽  
Resident Doctor

Background: Hypoglycemia may rarely present as hemiparesis and sometimes it is difficult to differentiate from ischemic stroke. When random blood sugar (RBS) value is between 50 and 80 mg % in patients presenting with focal neurological deficit, no guideline exists to consider the possibility of hypoglycemia before initiating thrombolytic therapy. Clinical Case: A 58-year-old male, who was a known case of diabetes and hypertension, was brought to the emergency room with acute onset of right hemiparesis and dysarthria of 90 minutes duration. His NIHSS Score was 9, blood pressure was 150/90 mm of Hg and RBS was 79 mg% on admission. His CT scan brain was normal and was considered for thrombolysis. Resident doctor not aware of previous sugar repeated RBS before thrombolysis which was surprisingly 60 mg% 60 minutes after the first RBS. Even though he was a candidate for thrombolysis, intravenous 25 % dextrose was administered considering the possibility of hypoglycemia. He made a complete recovery within 20 minutes and thrombolytic therapy was withheld. : In Diabetic patients with focal neurological deficit and RBS less than 80 mg% on admission, RBS should be rechecked and in appropriate cases should be challenged with IV dextrose considering the possibility of hypoglycemia before commencing thrombolytic therapy.

Central ossifying fibroma of mandible

2020 ◽  
Vol 13 (12) ◽  
pp. e239286
Author(s):  
Kumar Nilesh ◽  
Prashant Punde ◽  
Nitin Shivajirao Patil ◽  
Amol Gautam
Keyword(s):  
Fibrous Tissue ◽  
Three Dimensional ◽  
Facial Asymmetry ◽  
Ossifying Fibroma ◽  
Mandible Reconstruction ◽  
Three Dimensional Printing ◽  
Osseous Lesion ◽  
Large Size ◽  
Dimensional Printing

Ossifying fibroma (OF) is a rare, benign, fibro-osseous lesion of the jawbone characterised by replacement of the normal bone with fibrous tissue. The fibrous tissue shows varying amount of calcified structures resembling bone and/or cementum. The central variant of OF is rare, and shows predilection for mandible among the jawbone. Although it is classified as fibro-osseous lesion, it clinically behaves as a benign tumour and can grow to large size, causing bony swelling and facial asymmetry. This paper reports a case of large central OF of mandible in a 40-year-old male patient. The lesion was treated by segmental resection of mandible. Reconstruction of the surgical defect was done using avascular fibula bone graft. Role of three-dimensional printing of jaw and its benefits in surgical planning and reconstruction are also highlighted.

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