Synergetic Role of Hypromellose and Methacrylic Acid Copolymer in the Dissolution Improvement of Amorphous Solid Dispersions

Acid Copolymer

Insights into the Release Mechanisms of ITZ:HPMCAS Amorphous Solid Dispersions: The Role of Drug-Rich Colloids

10.1021/acs.molpharmaceut.1c00578 ◽

2021 ◽

Author(s):

Patrícia D. Nunes ◽

João F. Pinto ◽

João Henriques ◽

A. Mafalda Paiva

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Release Mechanisms

Balancing Solid-State Stability and Dissolution Performance of Lumefantrine Amorphous Solid Dispersions: The Role of Polymer Choice and Drug–Polymer Interactions

10.1021/acs.molpharmaceut.1c00481 ◽

2021 ◽

Author(s):

Tze Ning Hiew ◽

Dmitry Y. Zemlyanov ◽

Lynne S. Taylor

Keyword(s):

Solid State ◽

Solid Dispersions ◽

Amorphous Solid ◽

Solid State Stability ◽

Polymer Interactions

Congruent Release of Drug and Polymer from Amorphous Solid Dispersions: Insights into the Role of Drug-Polymer Hydrogen Bonding, Surface Crystallization, and Glass Transition

10.1021/acs.molpharmaceut.9b01272 ◽

2020 ◽

Vol 17 (4) ◽

pp. 1261-1275 ◽

Cited By ~ 8

Author(s):

Sugandha Saboo ◽

Umesh S. Kestur ◽

Daniel P. Flaherty ◽

Lynne S. Taylor

Keyword(s):

Hydrogen Bonding ◽

Glass Transition ◽

Solid Dispersions ◽

Amorphous Solid ◽

Surface Crystallization ◽

Bonding Surface

Role of Permeability on the Biopredictive Dissolution of Amorphous Solid Dispersions

AAPS PharmSciTech ◽

10.1208/s12249-021-02125-4 ◽

2021 ◽

Vol 22 (7) ◽

Author(s):

Gayathri Ramachandran ◽

M. S. Sudheesh

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

The role of polymers and excipients in developing amorphous solid dispersions: An industrial perspective

Drug Delivery Aspects ◽

10.1016/b978-0-12-821222-6.00005-1 ◽

2020 ◽

pp. 79-113 ◽

Cited By ~ 2

Author(s):

Vaibhav Sihorkar ◽

Thomas Dürig

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Structural and Dynamic Properties of Amorphous Solid Dispersions: The Role of Solid-State Nuclear Magnetic Resonance Spectroscopy and Relaxometry

Journal of Pharmaceutical Sciences ◽

10.1002/jps.23966 ◽

2014 ◽

Vol 103 (9) ◽

pp. 2635-2662 ◽

Cited By ~ 68

Author(s):

Amrit Paudel ◽

Marco Geppi ◽

Guy Van den Mooter

Keyword(s):

Nuclear Magnetic Resonance ◽

Solid State ◽

Magnetic Resonance ◽

Magnetic Resonance Spectroscopy ◽

Dynamic Properties ◽

Solid Dispersions ◽

Amorphous Solid ◽

Resonance Spectroscopy ◽

Insights into the Dissolution Behavior of Ledipasvir–Copovidone Amorphous Solid Dispersions: Role of Drug Loading and Intermolecular Interactions

10.1021/acs.molpharmaceut.9b01025 ◽

2019 ◽

Vol 16 (12) ◽

pp. 5054-5067 ◽

Cited By ~ 13

Author(s):

Chailu Que ◽

Xiaochun Lou ◽

Dmitry Y. Zemlyanov ◽

Huaping Mo ◽

Anura S. Indulkar ◽

...

Keyword(s):

Intermolecular Interactions ◽

Drug Loading ◽

Solid Dispersions ◽

Amorphous Solid ◽

Dissolution Behavior ◽

Phase Behavior of Drug-Hydroxypropyl Methylcellulose Amorphous Solid Dispersions Produced from Various Solvent Systems: Mechanistic Understanding of the Role of Polymer using Experimental and Theoretical Methods

10.1021/acs.molpharmaceut.8b00324 ◽

2018 ◽

Vol 15 (8) ◽

pp. 3236-3251 ◽

Cited By ~ 8

Author(s):

Naila A. Mugheirbi ◽

Laura I. Mosquera-Giraldo ◽

Carlos H. Borca ◽

Lyudmila V. Slipchenko ◽

Lynne S. Taylor

Keyword(s):

Phase Behavior ◽

Solid Dispersions ◽

Hydroxypropyl Methylcellulose ◽

Amorphous Solid ◽

Theoretical Methods ◽

Solvent Systems ◽

Mechanistic Understanding

Molecular Mobility as a Polymer Selection Tool for Amorphous Solid Dispersions

10.26226/morressier.57d6b2b6d462b8028d88e3c5 ◽

2016 ◽

Author(s):

Pinal Mistry

Keyword(s):

Molecular Mobility ◽

Solid Dispersions ◽

Amorphous Solid ◽

Selection Tool

Drug Dissolution Enhancement via Nanocomposites vs. Amorphous Solid Dispersions Prepared by Nanoextrusion Process

10.26226/morressier.57d6b2b8d462b8028d88d8de ◽

2016 ◽

Author(s):

Meng Li

Keyword(s):

Solid Dispersions ◽

Amorphous Solid ◽

Drug Dissolution ◽

Dissolution Enhancement ◽