Prediction of Apparent Oral Clearance of Small-Molecule Inhibitors in Pediatric Patients

Journal of Pharmaceutical Sciences ◽

10.1016/j.xphs.2017.11.001 ◽

2018 ◽

Vol 107 (3) ◽

pp. 949-956

Author(s):

Yoshihiko Kimura ◽

Yugo Chisaki ◽

Tomohiko Saki ◽

Chikako Matsumura ◽

Hideyuki Motohashi ◽

...

Keyword(s):

Small Molecule ◽

Pediatric Patients ◽

Small Molecule Inhibitors ◽

Oral Clearance ◽

Apparent Oral Clearance

Download Full-text

From molecular diagnostics to molecular targeted therapy with natural product small molecule inhibitors in oral squamous cell carcinoma

Planta Medica ◽

10.1055/s-2007-986722 ◽

2007 ◽

Vol 73 (09) ◽

Author(s):

VB Konkimalla ◽

VL Suhas ◽

NR Chandra ◽

E Gebhart ◽

T Efferth

Keyword(s):

Squamous Cell Carcinoma ◽

Targeted Therapy ◽

Oral Squamous Cell Carcinoma ◽

Cell Carcinoma ◽

Natural Product ◽

Molecular Diagnostics ◽

Small Molecule ◽

Squamous Cell ◽

Molecular Targeted Therapy ◽

Small Molecule Inhibitors

Download Full-text

Faculty Opinions recommendation of Nanomolar small molecule inhibitors for alphav(beta)6, alphav(beta)5, and alphav(beta)3 integrins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1004750.54854 ◽

2002 ◽

Author(s):

Carol Otey

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors

Download Full-text

Faculty Opinions recommendation of Identification of small molecule inhibitors of anthrax lethal factor.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1016978.201559 ◽

2004 ◽

Author(s):

Kristina Downing

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Lethal Factor ◽

Anthrax Lethal Factor

Download Full-text

Faculty Opinions recommendation of Harnessing chaperones to generate small-molecule inhibitors of amyloid beta aggregation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1017973.285766 ◽

2005 ◽

Author(s):

George Perry

Keyword(s):

Small Molecule ◽

Amyloid Beta ◽

Small Molecule Inhibitors

Download Full-text

Faculty Opinions recommendation of High-affinity small molecule inhibitors of T cell costimulation: compounds for immunotherapy.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1023153.264839 ◽

2005 ◽

Author(s):

Robert Kelley

Keyword(s):

T Cell ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

Download Full-text

Faculty Opinions recommendation of Novel small molecule inhibitors of 3-phosphoinositide-dependent kinase-1.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1024840.292879 ◽

2005 ◽

Author(s):

Chandra Kumar

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors ◽

Phosphoinositide Dependent Kinase

Download Full-text

Faculty Opinions recommendation of Identification of new small molecule inhibitors of cystic fibrosis transmembrane conductance regulator protein: in vitro and in vivo studies.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.1069767.522696 ◽

2007 ◽

Author(s):

Kim Barrett

Keyword(s):

Cystic Fibrosis ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

In Vivo Studies ◽

Transmembrane Conductance Regulator ◽

Transmembrane Conductance ◽

Regulator Protein ◽

Cystic Fibrosis Transmembrane

Download Full-text

Faculty Opinions recommendation of Discovery and characterization of small molecule inhibitors of the BET family bromodomains.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.13411091.14784061 ◽

2011 ◽

Author(s):

Martin Stahl

Keyword(s):

Small Molecule ◽

Small Molecule Inhibitors

Download Full-text

Faculty Opinions recommendation of Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3462958.3157056 ◽

2010 ◽

Author(s):

Jim Maher

Keyword(s):

Small Molecule ◽

Rational Design ◽

Small Molecule Inhibitors ◽

Hiv Replication

Download Full-text

Faculty Opinions recommendation of Reversible, allosteric small-molecule inhibitors of regulator of G protein signaling proteins.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.3767956.3494054 ◽

2010 ◽

Author(s):

Stephen Schwartz

Keyword(s):

G Protein ◽

Small Molecule ◽

Small Molecule Inhibitors ◽

G Protein Signaling ◽

Signaling Proteins ◽

Protein Signaling

Download Full-text