Lipid accumulation-induced hepatocyte senescence regulates the activation of hepatic stellate cells through the Nrf2-antioxidant response element pathway

Induction of the Nrf2-Antioxidant Response Element (ARE) Pathway in Cultured Hepatic Stellate Cells (HSCs) Leads to Increased Markers of HSC Activation

Journal of Surgical Research ◽

10.1016/j.jss.2013.11.872 ◽

2014 ◽

Vol 186 (2) ◽

pp. 678

Author(s):

L.N. Taylor ◽

L. Lee ◽

L. Zhang ◽

J.A. Johnson ◽

D.P. Foley

Keyword(s):

Hepatic Stellate Cells ◽

Stellate Cells ◽

Antioxidant Response ◽

Induction of the Nrf2-Antioxidant Response Element Pathway (ARE) in Hepatic Stellate Cells Protects Hepatocytes from Oxidative Stress-Induced Injury

Journal of Surgical Research ◽

10.1016/j.jss.2011.11.282 ◽

2012 ◽

Vol 172 (2) ◽

pp. 205-206

Author(s):

D.P. Foley ◽

S.E. Nelson ◽

D.A. Johnson ◽

J.A. Johnson

Keyword(s):

Oxidative Stress ◽

Hepatic Stellate Cells ◽

Stellate Cells ◽

Antioxidant Response ◽

Overexpression of the Nrf2-Antioxidant Response Element (ARE) Pathway in Hepatic Stellate Cells (HSCs) Ameliorates the Development of Non-Alcoholic Steatohepatitis (NASH) in Mice

Journal of Surgical Research ◽

10.1016/j.jss.2013.11.445 ◽

2014 ◽

Vol 186 (2) ◽

pp. 548

Author(s):

L. Lee ◽

L. Zhang ◽

D. Roenneburg ◽

J.A. Johnson ◽

D.P. Foley

Keyword(s):

Hepatic Stellate Cells ◽

Stellate Cells ◽

Antioxidant Response ◽

Response Element ◽

Alcoholic Steatohepatitis

Lipid accumulation in hepatocytes induces activation and pro-fibrotic gene expression in hepatic stellate cells.–A new in vitro model to study fibrogenesis in hepatic steatosis

Zeitschrift für Gastroenterologie ◽

10.1055/s-2008-1037459 ◽

2008 ◽

Vol 46 (01) ◽

Author(s):

H Wobser ◽

C Dorn ◽

T Weiss ◽

T Amann ◽

C Bollheimer ◽

...

Keyword(s):

Gene Expression ◽

Hepatic Steatosis ◽

Hepatic Stellate Cells ◽

Lipid Accumulation ◽

In Vitro Model ◽

Stellate Cells ◽

Vitro Model

Serum Choice Influences Lipid Accumulation and Cell Viability in Fatty Acid Treated Immortalised Hepatocytes and Hepatic Stellate Cells

10.26226/morressier.5ef37080b2a27f760262bb43 ◽

2020 ◽

Author(s):

Zixuan Zhang ◽

James Thorne ◽

J Bernadette Moore

Keyword(s):

Fatty Acid ◽

Cell Viability ◽

Hepatic Stellate Cells ◽

Lipid Accumulation ◽

Stellate Cells

Induction of activation of the antioxidant response element and stabilization of Nrf2 by 3-(3-pyridylmethylidene)-2-indolinone (PMID) confers protection against oxidative stress-induced cell death

Toxicology and Applied Pharmacology ◽

10.1016/j.taap.2011.12.027 ◽

2012 ◽

Vol 259 (2) ◽

pp. 227-235 ◽

Cited By ~ 13

Author(s):

Jia-Wei Yao ◽

Jing Liu ◽

Xiang-Zhen Kong ◽

Shou-Guo Zhang ◽

Xiao-Hui Wang ◽

...

Keyword(s):

Oxidative Stress ◽

Cell Death ◽

Antioxidant Response ◽

Transcriptional regulation of a rat liver glutathione S-transferase Ya subunit gene. Analysis of the antioxidant response element and its activation by the phorbol ester 12-O-tetradecanoylphorbol-13-acetate.

Journal of Biological Chemistry ◽

10.1016/s0021-9258(17)36880-1 ◽

1994 ◽

Vol 269 (18) ◽

pp. 13656-13662 ◽

Cited By ~ 2

Author(s):

T. Nguyen ◽

T.H. Rushmore ◽

C.B. Pickett

Keyword(s):

Transcriptional Regulation ◽

Rat Liver ◽

Phorbol Ester ◽

Antioxidant Response ◽

Gene Analysis ◽

Subunit Gene ◽

Glutathione S Transferase ◽

Response Element ◽

Liver Glutathione

Induction of the Protective Antioxidant Response Element Pathway by 6-Hydroxydopamine In Vivo and In Vitro

Toxicological Sciences ◽

10.1093/toxsci/kfi241 ◽

2005 ◽

Vol 87 (1) ◽

pp. 176-186 ◽

Cited By ~ 45

Author(s):

Rebekah J. Jakel ◽

Jonathan T. Kern ◽

Delinda A. Johnson ◽

Jeffrey A. Johnson

Keyword(s):

Antioxidant Response ◽

Response Element ◽

6 Hydroxydopamine

Homocysteine stimulates antioxidant response element-mediated expression of glutamate-cysteine ligase in mouse macrophages

Atherosclerosis ◽

10.1016/j.atherosclerosis.2008.06.024 ◽

2009 ◽

Vol 203 (1) ◽

pp. 105-111 ◽

Cited By ~ 16

Author(s):

Florian Bea ◽

Francesca N. Hudson ◽

Haley Neff-LaFord ◽

Collin C. White ◽

Terrance J. Kavanagh ◽

...

Keyword(s):

Antioxidant Response ◽

Glutamate Cysteine Ligase ◽

Response Element ◽

Mouse Macrophages

Characterization of Nrf1b, a Novel Isoform of the Nuclear Factor-Erythroid-2 Related Transcription Factor-1 That Activates Antioxidant Response Element-Regulated Genes

PLoS ONE ◽

10.1371/journal.pone.0048404 ◽

2012 ◽

Vol 7 (10) ◽

pp. e48404 ◽

Cited By ~ 5

Author(s):

Eric K. Kwong ◽

Kyung-Mi Kim ◽

Patrick J. Penalosa ◽

Jefferson Y. Chan

Keyword(s):

Transcription Factor ◽

Antioxidant Response ◽

Nuclear Factor ◽

Response Element ◽

Related Transcription Factor ◽

Transcription Factor 1