Reduced CD147 expression is linked to ERG fusion-positive prostate cancers but lacks substantial impact on PSA recurrence in patients treated by radical prostatectomy

2013 ◽  
Vol 95 (2) ◽  
pp. 227-234 ◽  
Author(s):  
Katharina Grupp ◽  
Thorsten Simon Höhne ◽  
Kristina Prien ◽  
Claudia Hube-Magg ◽  
Maria Christina Tsourlakis ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Substantial Impact ◽  
Cd147 Expression ◽  
Psa Recurrence ◽  
Prostate Cancers

scholarly journals FOXA1 expression is a strong independent predictor of early PSA recurrence in ERG negative prostate cancers treated by radical prostatectomy

2017 ◽  
Vol 38 (12) ◽  
pp. 1180-1187 ◽  
Author(s):  
Maria Christina Tsourlakis ◽  
Agapi Eleftheriadou ◽  
Annegret Stender ◽  
Philipp Weigand ◽  
Katharina Grupp ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Independent Predictor ◽  
Psa Recurrence ◽  
Prostate Cancers ◽  
Strong Independent Predictor ◽  
Foxa1 Expression

1188: Time to PSA Recurrence after Radical Prostatectomy and Risk of Prostate Cancer Specific Mortality

2006 ◽  
Vol 175 (4S) ◽  
pp. 382-382
Author(s):  
Stephen J. Freedland ◽  
Elizabeth B. Humphreys ◽  
Leslie A. Mangold ◽  
Mario Eisenberger ◽  
Alan W. Partin
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Specific Mortality ◽  
Psa Recurrence ◽  
Cancer Specific Mortality

DELAYED PSA RECURRENCE AFTER RADICAL PROSTATECTOMY: HOW TO IDENTIFY PATIENTS AT RISK AND THEIR CLINICAL OUTCOMES?

2009 ◽  
Vol 181 (4S) ◽  
pp. 457-457
Author(s):  
Benjamin D Lack ◽  
Leon Sun ◽  
Arthur A Caire ◽  
Oludotun Ode ◽  
Danielle A Stackhouse ◽  
...  
Keyword(s):  
At Risk ◽  
Radical Prostatectomy ◽  
Clinical Outcomes ◽  
Patients At Risk ◽  
Psa Recurrence

Limited Sampling of Radical Prostatectomy Specimens With Excellent Preservation of Prognostic Parameters of Prostate Cancer

2009 ◽  
Vol 133 (8) ◽  
pp. 1278-1284
Author(s):  
Kyungeun Kim ◽  
Pil June Pak ◽  
Jae Y. Ro ◽  
Dongik Shin ◽  
Soo-Jin Huh ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Sampling Method ◽  
Resection Margin ◽  
Gleason Grade ◽  
Posterior Half ◽  
Margin Involvement ◽  
Partial Sampling ◽  
Prostate Cancers ◽  
Extraprostatic Extension

Abstract Context.—The widespread use of the serum prostate-specific antigen test has increased the early detection of prostate cancer and consequently reduced grossly definable prostate cancers. Objective.—To find the most efficient gross sampling method for radical prostatectomy specimens not only preserving important prognostic factors but also being cost effective. Design.—We initially analyzed clinicopathologic features of the entire prostate sections from 148 radical prostatectomy specimens, which then were used to examine the impact of 5 partial sampling methods on tumor stage, Gleason score, extraprostatic extension, resection margin status, and paraffin block numbers. The methods included submission of (1) alternative slices, (2) alternative slices plus biopsy-positive posterior quarters, (3) every posterior half, (4) every posterior half plus one midanterior half, and (5) alternative slices plus peripheral 3-mm rim of the remaining prostate. Results.—Prostate cancers and their extraprostatic extension and resection margin involvement were commonly located in the right posterior portion of the prostate. Method 5 was most efficient, detecting all cases with extraprostatic extension and resection margin involvement and reducing 25% of paraffin blocks compared with the entire sampling of the prostate. The Gleason scores were retained in most of cases, except reversal of the primary and secondary Gleason grade component in only 2 cases (1%). Only 4 cases (3%) were downstaged within the same T2 stage. Conclusions.—These results demonstrate that sampling of alternative slices plus peripheral rim of the remaining prostate is the most efficient partial sampling method for radical prostatectomy specimens.

scholarly journals Loss of SOX9 Expression Is Associated with PSA Recurrence in ERG-Positive and PTEN Deleted Prostate Cancers

PLoS ONE ◽  
2015 ◽  
Vol 10 (6) ◽  
pp. e0128525 ◽  
Author(s):  
Christoph Burdelski ◽  
Erzen Bujupi ◽  
Maria Christina Tsourlakis ◽  
Claudia Hube-Magg ◽  
Martina Kluth ◽  
...  
Keyword(s):  
Sox9 Expression ◽  
Psa Recurrence ◽  
Prostate Cancers

scholarly journals Prognostic significance of a novel indicator (PSApostd3/PSApre) for PSA recurrence in patients after radical prostatectomy

2019 ◽  
Vol Volume 11 ◽  
pp. 5777-5783
Author(s):  
Zhien Zhou ◽  
Yinyan Xu ◽  
Qianyue Li ◽  
Weigang Yan ◽  
Yi Zhou ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
Prognostic Significance ◽  
Psa Recurrence

Quantification of total and high-grade cancer in biopsy cores improves the prediction of PSA recurrence after Radical Prostatectomy (RP)

2002 ◽  
Vol 1 (1) ◽  
pp. 119
Author(s):  
Peter Hammerer ◽  
Markus Graefen ◽  
Pierre Karakiewicz ◽  
Salvador Fernandez ◽  
Makoto Ohori ◽  
...  
Keyword(s):  
Radical Prostatectomy ◽  
High Grade ◽  
Psa Recurrence

scholarly journals Exploring Prostate Cancer Genome Reveals Simultaneous Losses of PTEN, FAS and PAPSS2 in Patients with PSA Recurrence after Radical Prostatectomy

2015 ◽  
Vol 16 (2) ◽  
pp. 3856-3869 ◽  
Author(s):  
Chinyere Ibeawuchi ◽  
Hartmut Schmidt ◽  
Reinhard Voss ◽  
Ulf Titze ◽  
Mahmoud Abbas ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Cancer Genome ◽  
Psa Recurrence
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