Metabolic engineering of light-driven cytochrome P450 dependent pathways into Synechocystis sp. PCC 6803

2016 ◽  
Vol 33 ◽  
pp. 1-11 ◽  
Author(s):  
Artur Wlodarczyk ◽  
Thiyagarajan Gnanasekaran ◽  
Agnieszka Zygadlo Nielsen ◽  
Nodumo Nokolunga Zulu ◽  
Silas Busck Mellor ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Metabolic Engineering ◽  
Synechocystis Sp ◽  
Pcc 6803

scholarly journals Metabolic engineering of Synechocystis sp. PCC 6803 for the production of aromatic amino acids and derived phenylpropanoids

2020 ◽  
Vol 57 ◽  
pp. 129-139 ◽  
Author(s):  
Laura Furelos Brey ◽  
Artur J. Włodarczyk ◽  
Jens F. Bang Thøfner ◽  
Meike Burow ◽  
Christoph Crocoll ◽  
...  
Keyword(s):  
Amino Acids ◽  
Metabolic Engineering ◽  
Aromatic Amino Acids ◽  
Synechocystis Sp ◽  
Pcc 6803

scholarly journals A Comparison of Constitutive and Inducible Non-Endogenous Keto-Carotenoids Biosynthesis in Synechocystis sp. PCC 6803

2019 ◽  
Vol 7 (11) ◽  
pp. 501 ◽  
Author(s):  
Menin ◽  
Lami ◽  
Musazzi ◽  
Petrova ◽  
Santabarbara ◽  
...  
Keyword(s):  
Metabolic Engineering ◽  
Biosynthetic Pathway ◽  
Wide Spectrum ◽  
Industrial Applications ◽  
Inducible Expression ◽  
Added Value ◽  
Significant Attention ◽  
Synechocystis Sp ◽  
Carotenoid Biosynthetic Pathway ◽  
Pcc 6803

The model cyanobacterium Synechocystis sp. PCC 6803 has gained significant attention as an alternative and sustainable source for biomass, biofuels and added-value compounds. The latter category includes keto-carotenoids, which are molecules largely employed in a wide spectrum of industrial applications in the food, feed, nutraceutical, cosmetic and pharmaceutical sectors. Keto-carotenoids are not naturally synthesized by Synechocystis, at least in any significant amounts, but their accumulation can be induced by metabolic engineering of the endogenous carotenoid biosynthetic pathway. In this study, the accumulation of the keto-carotenoids astaxanthin and canthaxanthin, resulting from the constitutive or temperature-inducible expression of the CrtW and CrtZ genes from Brevundimonas, is compared. The benefits and drawbacks of the two engineering approaches are discussed.

A retinoic acid binding cytochrome P450: CYP120A1 from Synechocystis sp. PCC 6803

2005 ◽  
Vol 436 (1) ◽  
pp. 110-120 ◽  
Author(s):  
Na Ke ◽  
Jerome Baudry ◽  
Thomas M. Makris ◽  
Mary A. Schuler ◽  
Stephen G. Sligar
Keyword(s):  
Cytochrome P450 ◽  
Retinoic Acid ◽  
Synechocystis Sp ◽  
Pcc 6803
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