Metabolic engineering of enhanced glycerol-3-phosphate synthesis to increase lipid production in Synechocystis sp. PCC 6803

2016 ◽  
Vol 100 (13) ◽  
pp. 6091-6101 ◽  
Author(s):  
Xi Wang ◽  
Xiaochao Xiong ◽  
Na Sa ◽  
Sanja Roje ◽  
Shulin Chen
2020 ◽  
Vol 57 ◽  
pp. 129-139 ◽  
Author(s):  
Laura Furelos Brey ◽  
Artur J. Włodarczyk ◽  
Jens F. Bang Thøfner ◽  
Meike Burow ◽  
Christoph Crocoll ◽  
...  

2016 ◽  
Vol 33 ◽  
pp. 1-11 ◽  
Author(s):  
Artur Wlodarczyk ◽  
Thiyagarajan Gnanasekaran ◽  
Agnieszka Zygadlo Nielsen ◽  
Nodumo Nokolunga Zulu ◽  
Silas Busck Mellor ◽  
...  

2019 ◽  
Vol 7 (11) ◽  
pp. 501 ◽  
Author(s):  
Menin ◽  
Lami ◽  
Musazzi ◽  
Petrova ◽  
Santabarbara ◽  
...  

The model cyanobacterium Synechocystis sp. PCC 6803 has gained significant attention as an alternative and sustainable source for biomass, biofuels and added-value compounds. The latter category includes keto-carotenoids, which are molecules largely employed in a wide spectrum of industrial applications in the food, feed, nutraceutical, cosmetic and pharmaceutical sectors. Keto-carotenoids are not naturally synthesized by Synechocystis, at least in any significant amounts, but their accumulation can be induced by metabolic engineering of the endogenous carotenoid biosynthetic pathway. In this study, the accumulation of the keto-carotenoids astaxanthin and canthaxanthin, resulting from the constitutive or temperature-inducible expression of the CrtW and CrtZ genes from Brevundimonas, is compared. The benefits and drawbacks of the two engineering approaches are discussed.


2019 ◽  
Vol 12 (1) ◽  
Author(s):  
Kamonchanock Eungrasamee ◽  
Rui Miao ◽  
Aran Incharoensakdi ◽  
Peter Lindblad ◽  
Saowarath Jantaro

2018 ◽  
Vol 8 (1) ◽  
Author(s):  
Umaporn Towijit ◽  
Nutchaya Songruk ◽  
Peter Lindblad ◽  
Aran Incharoensakdi ◽  
Saowarath Jantaro

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