Relation of Menstrual Losses to Iron Requirement

1949 ◽  
Vol 25 (3) ◽  
pp. 217-220
Author(s):  
Ruth Frenchman ◽  
Frances A. Johnston
Keyword(s):  
1986 ◽  
Vol 3 (5) ◽  
pp. 299-309 ◽  
Author(s):  
I.Q. Thomson ◽  
D.L. Collins-Thompson

1978 ◽  
Vol 44 (3-4) ◽  
pp. 257-267 ◽  
Author(s):  
J. H. Marcelis ◽  
Hanneke J. den Daas-Slagt ◽  
Jacomina A. A. Hoogkamp-Korstanje

2008 ◽  
Vol 75 (5) ◽  
pp. 1229-1235 ◽  
Author(s):  
Iman A. El Gheriany ◽  
Daniela Bocioaga ◽  
Anthony G. Hay ◽  
William C. Ghiorse ◽  
Michael L. Shuler ◽  
...  

ABSTRACT A common form of biocatalysis of Mn(II) oxidation results in the formation of biogenic Mn(III, IV) oxides and is a key reaction in the geochemical cycling of Mn. In this study, we grew the model Mn(II)-oxidizing bacterium Leptothrix discophora SS-1 in media with limited iron (0.1 μM iron/5.8 mM pyruvate) and sufficient iron (0.2 μM iron/5.8 mM pyruvate). The influence of iron on the rate of extracellular Mn(II) oxidation was evaluated. Cultures in which cell growth was limited by iron exhibited reduced abilities to oxidize Mn(II) compared to cultures in medium with sufficient iron. While the extracellular Mn(II)-oxidizing factor (MOF) is thought to be a putative multicopper oxidase, Mn(II) oxidation in the presence of zero added Cu(II) was detected and the decrease in the observed Mn(II) oxidation rate in iron-limited cultures was not relieved when the medium was supplemented with Cu(II). The decline of Mn(II) oxidation under iron-limited conditions was not accompanied by siderophore production and is unlikely to be an artifact of siderophore complex formation with Mn(III). The temporal variations in mofA gene transcript levels under conditions of limited and abundant iron were similar, indicating that iron limitation did not interfere with the transcription of the mofA gene. Our quantitative PCR results provide a step forward in understanding the regulation of Mn(II) oxidation. The mechanistic role of iron in Mn(II) oxidation is uncertain; the data are consistent with a direct requirement for iron as a component of the MOF or an indirect effect of iron resulting from the limitation of one of many cellular functions requiring iron.


Author(s):  
Sir Peter Gluckman ◽  
Mark Hanson ◽  
Chong Yap Seng ◽  
Anne Bardsley

Iron requirements increase approximately 2.5-fold by the end of pregnancy, representing the largest relative increase in nutrient requirements for pregnant women. The total additional iron requirement in the third trimester is 9#amp;#x2013;12 mg/day above pre-pregnancy needs, and even with this additional intake, women need to enter pregnancy with iron stores of approximately 500 mg to be able to fully meet the demands of pregnancy. The prevalence of iron deficiency and anaemia is therefore very high among pregnant women and can result in cognitive and motor deficits in the infant that may be irreversible. Prevention of deficiency is therefore critical. Building sufficient iron stores prior to conception is preferable, as it is difficult to obtain adequate iron from diet alone to meet late pregnancy requirements. Iron supplementation of 30 mg/day should be considered, particularly if dietary intake of meat is low.


Blood ◽  
1969 ◽  
Vol 33 (3) ◽  
pp. 421-429 ◽  
Author(s):  
J. D. COOK ◽  
M. LAYRISSE ◽  
C. A. FINCH

Abstract Sources of variation in iron absorption measurements and methods of controlling them have been reviewed. There are marked differences in the mean level of absorption in different individuals and appreciable day-to-day variation in absorption in the same individual. Intersubject variations can be reduced by the selection of individuals with a more uniform iron requirement, but large variations remain which can be dealt with only by applying appropriate statistical methods to the skewed data obtained and by studying sufficient subjects to provide statistical validity to the results. Comparative studies of the availability of food iron are best carried out against a reference standard in the same subject, and intrasubject variations can be reduced by multiple dose administration.


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