Separation and determination of homovanillic acid and vanillylmandelic acid by capillary electrophoresis with electrochemical detection

2002 ◽  
Vol 461 (1) ◽  
pp. 123-130 ◽  
Author(s):  
Xiujun Li ◽  
Wenrui Jin ◽  
Qianfeng Weng
Keyword(s):  
Capillary Electrophoresis ◽  
Electrochemical Detection ◽  
Homovanillic Acid ◽  
Vanillylmandelic Acid

Determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid in dried urine on filter-paper discs by high-performance liquid chromatography with coulometric electrochemical detection for neuroblastoma screening.

1988 ◽  
Vol 34 (11) ◽  
pp. 2228-2230 ◽  
Author(s):  
Y Kinoshita ◽  
S Yamada ◽  
K Haraguchi ◽  
T Takayanagi ◽  
Y Mori ◽  
...  
Keyword(s):  
High Performance Liquid Chromatography ◽  
Liquid Chromatography ◽  
Electrochemical Detection ◽  
Filter Paper ◽  
High Performance ◽  
Homovanillic Acid ◽  
Vanillylmandelic Acid ◽  
Chromatographic Procedure ◽  
One Year

Abstract We report a method for determination of vanillylmandelic acid, vanillactic acid, and homovanillic acid by high-performance liquid chromatography (HPLC), with coulometric electrochemical detection, for mass screening of neuroblastoma. Urine samples were collected on filter paper, dried, and then pretreated. The chromatographic procedure is reliable and fast, allowing for a large sample throughput for routine screening. Intricate extraction procedures and centrifugal separation are unnecessary. Screening for neuroblastoma by HPLC is rapidly gaining acceptance in Japan, and our method is being used at many screening centers. Of 26,571 infants screened in one year in Yokohama City, our method detected five with neuroblastoma.

Determination of Bioactive Components inPolygonum perfoliatumL. by Capillary Electrophoresis with Electrochemical Detection

2009 ◽  
Vol 27 (4) ◽  
pp. 773-776 ◽  
Author(s):  
Shuping JIN ◽  
Xifeng GUO ◽  
Yinyan ZHANG ◽  
Ping LI ◽  
Pingang HE ◽  
...  
Keyword(s):  
Capillary Electrophoresis ◽  
Electrochemical Detection ◽  
Bioactive Components

Liquid-chromatographic method for determination of homovanillic acid in plasma, with electrochemical detection.

1987 ◽  
Vol 33 (1) ◽  
pp. 72-75 ◽  
Author(s):  
M Zumárraga ◽  
I Andia ◽  
B Bárcena ◽  
M I Zamalloa ◽  
R Dávilla
Keyword(s):  
Electrochemical Detection ◽  
Homovanillic Acid ◽  
Chromatographic Method ◽  
Detection Sensitivity ◽  
Simple Method ◽  
Liquid Chromatographic Method ◽  
Analytical Recovery ◽  
Standard Additions ◽  
Liquid Chromatographic

Abstract We describe a sensitive, simple method for measuring homovanillic acid in human plasma. The method is based on liquid chromatography with electrochemical detection. Sensitivity was 125 pg of homovanillic acid per injection. Samples were deproteinized and extracted with organic solvent before chromatography. Quantification was by the standard-additions technique. Analytical recovery of added HVA was 44.8 (SD 6.2%). We confirmed specificity by using serial amperometric detectors.

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