scholarly journals The menD and menE homologs code for 2-succinyl-6-hydroxyl-2,4-cyclohexadiene-1-carboxylate synthase and O-succinylbenzoic acid–CoA synthase in the phylloquinone biosynthetic pathway of Synechocystis sp. PCC 6803

2003 ◽  
Vol 1557 ◽  
pp. 67-76 ◽  
Author(s):  
T Wade Johnson ◽  
Sushma Naithani ◽  
Charles Stewart ◽  
Boris Zybailov ◽  
A Daniel Jones ◽  
...  
2019 ◽  
Vol 7 (11) ◽  
pp. 501 ◽  
Author(s):  
Menin ◽  
Lami ◽  
Musazzi ◽  
Petrova ◽  
Santabarbara ◽  
...  

The model cyanobacterium Synechocystis sp. PCC 6803 has gained significant attention as an alternative and sustainable source for biomass, biofuels and added-value compounds. The latter category includes keto-carotenoids, which are molecules largely employed in a wide spectrum of industrial applications in the food, feed, nutraceutical, cosmetic and pharmaceutical sectors. Keto-carotenoids are not naturally synthesized by Synechocystis, at least in any significant amounts, but their accumulation can be induced by metabolic engineering of the endogenous carotenoid biosynthetic pathway. In this study, the accumulation of the keto-carotenoids astaxanthin and canthaxanthin, resulting from the constitutive or temperature-inducible expression of the CrtW and CrtZ genes from Brevundimonas, is compared. The benefits and drawbacks of the two engineering approaches are discussed.


1991 ◽  
Vol 266 (17) ◽  
pp. 11111-11115
Author(s):  
M. Ikeuchi ◽  
B. Eggers ◽  
G.Z. Shen ◽  
A. Webber ◽  
J.J. Yu ◽  
...  

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