A Single Administration of Dehydroepiandrosterone Does Not Enhance Memory Performance in Young Healthy Adults, but Immediately Reduces Cortisol Levels

1997 ◽  
Vol 42 (9) ◽  
pp. 845-848 ◽  
Author(s):  
Oliver T Wolf ◽  
Birthe Köster ◽  
Clemens Kirschbaum ◽  
Reinhard Pietrowsky ◽  
Werner Kern ◽  
...  
Keyword(s):  
Memory Performance ◽  
Healthy Adults ◽  
Single Administration ◽  
Cortisol Levels

scholarly journals Effect of cortisol levels on working memory performance in elderly subjects with Alzheimer's disease

2008 ◽  
Vol 66 (3b) ◽  
pp. 619-624 ◽  
Author(s):  
Juliana Nery de Souza-Talarico ◽  
Paulo Caramelli ◽  
Ricardo Nitrini ◽  
Eliane Corrêa Chaves
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Working Memory ◽  
Digit Span ◽  
Memory Performance ◽  
Elderly Subjects ◽  
Control Group ◽  
Acute Administration ◽  
Healthy Elderly ◽  
Cortisol Levels

BACKGROUND: Subjects with Alzheimer's disease (AD) have elevated cortisol levels as a result of hypothalamic-pituitary-adrenal (HPA) axis dysfunction. Acute administration of hydrocortisone has been associated with working memory (WM) performance in young adults. OBJECTIVE: To investigate whether cortisol levels are associated with WM performance in subjects with AD. METHOD: Eighty subjects were included, comprising 40 patients with mild AD and 40 healthy elderly controls. WM was assessed using the Digit Span Backward test (DSB). Saliva samples were collected to determine cortisol levels. RESULTS: AD subjects had poorer performance on the DSB than controls (p=0.002) and also presented higher levels of cortisol than control group (p=0.04). No significant correlation was observed between the DSB and cortisol levels in both groups (r= -0.29). CONCLUSION: In this study, elevated cortisol levels were not associated with poorer WM performance in patients with AD or in healthy elderly subjects.

scholarly journals Anxiety mediates the effect of acute stress on working memory performance when cortisol levels are high: a moderated mediation analysis

2015 ◽  
Vol 28 (5) ◽  
pp. 545-562 ◽  
Author(s):  
Anna Hood ◽  
Kim Pulvers ◽  
Thomas J. Spady ◽  
Alexa Kliebenstein ◽  
Jennifer Bachand
Keyword(s):  
Working Memory ◽  
Mediation Analysis ◽  
Acute Stress ◽  
Memory Performance ◽  
Moderated Mediation ◽  
Cortisol Levels

Acute and long-term associations between ApoE genetic polymorphism, cortisol levels, and declarative memory performance in older adults

2008 ◽  
Vol 33 (5) ◽  
pp. 625-633 ◽  
Author(s):  
Alexandra J. Fiocco ◽  
Judes Poirier ◽  
Ridha Joober ◽  
N.P.V. Nair ◽  
Sonia J. Lupien
Keyword(s):  
Older Adults ◽  
Genetic Polymorphism ◽  
Declarative Memory ◽  
Memory Performance ◽  
Cortisol Levels

F1-02-04: Connectivity within the default mode network is related to working memory performance in young but not elderly healthy adults

2012 ◽  
Vol 8 (4S_Part_2) ◽  
pp. P81-P81
Author(s):  
Igor Yakushev ◽  
Gaël Chetelat ◽  
Florian Fischer ◽  
Brigitte Landeau ◽  
Christine Bastin ◽  
...  
Keyword(s):  
Working Memory ◽  
Default Mode Network ◽  
Memory Performance ◽  
Healthy Adults ◽  
Default Mode

scholarly journals Marital status as a predictor of diurnal salivary cortisol levels and slopes in a community sample of healthy adults

2017 ◽  
Vol 78 ◽  
pp. 68-75 ◽  
Author(s):  
Brian Chin ◽  
Michael L.M. Murphy ◽  
Denise Janicki-Deverts ◽  
Sheldon Cohen
Keyword(s):  
Marital Status ◽  
Salivary Cortisol ◽  
Community Sample ◽  
Healthy Adults ◽  
Cortisol Levels
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