Selected topics related to occupational exposures Part IX. Laboratory evaluation of low-level chemical or toxic exposures

2000 ◽  
Vol 46 (9) ◽  
pp. 617-645
Author(s):  
Robert H. Williams ◽  
Adam Negrusz
2019 ◽  
Vol 76 (Suppl 1) ◽  
pp. A24.1-A24
Author(s):  
Tea Lallukka ◽  
Leena Kaila-Kangas ◽  
Minna Mänty ◽  
Johanna Seppänen ◽  
Eija Haukka ◽  
...  

BackgroundPhysical workload factors have been linked to the risk of sickness absence, however, some work exposures can also be protective of work ability. We aimed to first identify sickness absence trajectories in a nationally representative occupational cohort, and second to examine the associations between physical workload factors, potential protective factors and sickness absence trajectories.MethodsWe examined a nationally representative cohort of working aged Finnish adults interviewed and medically examined at baseline in 2000–2001 (n=3814). Both potentially protective (sitting and keyboard use) and risk factors (e.g. handling of heavy loads and vibration) were included. All medically confirmed sickness absence periods 2002–2008 were included in the trajectory analyses to identify latent groups with similar sickness absence trends. These data were derived from the registers of the Social Insurance Institution of Finland. The models were adjusted for sociodemographic factors, health behaviors and physical and mental health.ResultsWe found a group with a very low level, a group with a stable low level, and a group with a high and increasing level of sickness absence. After full adjustments, prolonged sitting and use of keyboard emerged as protective factors that were associated with a lower risk of belonging to the trajectory with high and increasing sickness absence (HR 0.60; 95% CI 0.45–0.80). In turn, the risk increased with the number of physical workload factors reported, and was highest for those with four or more workload factors (HR 2.84; 95% 2.08–3.88).ConclusionsPhysical work is associated with the risk of long-term sickness absence, with the highest risk found for those with several different physical workload factors. As the risk remained after controlling for various pertinent risk factors, this highlights the need to find ways to better maintain work ability of those with the physically most strenuous work.


2020 ◽  
Vol 2020 ◽  
pp. 1-5
Author(s):  
Jason S. Oh ◽  
Uni Wong ◽  
Divyansh Bajaj ◽  
Stella E. Hines

We present a case report of a patient with Isolated pauci-immune pulmonary capillaritis (IPIPC). A 40-year-old male presented with acute onset severe hypoxemic respiratory failure. He had just returned home from work as a cabinetmaker, where he experienced inhalational exposure to hydrocarbons and solvents, and had smoked a marijuana cigarette. He was hypotensive, and his chest imaging showed bilateral dependent infiltrates. His hypoxemia made little improvement after conventional ventilator support and broad-spectrum antibacterial therapy and he was considered too unstable to tolerate diagnostic bronchoscopy with bronchoalveolar lavage. His laboratory evaluation initially showed microscopic hematuria which later cleared, but other tests including serologic autoimmune assessment were negative, and he did not have any traditional risk factors for vasculitis. A video-assisted thoracoscopic lung biopsy revealed diffuse alveolar hemorrhage with pulmonary capillaritis on histopathology. He was diagnosed with IPIPC and initiated on immunosuppressive therapy. He was soon liberated from mechanical ventilation and improved to hospital discharge. Diffuse alveolar hemorrhage from Goodpasture’s Syndrome has manifested following inhalation of hydrocarbons and following smoking. This has not previously been reported with IPIPC. Given the lack of other findings and risk factors, his IPIPC was likely associated with occupational exposures to hydrocarbons as a cabinetmaker compounded by marijuana smoking.


BMJ Open ◽  
2021 ◽  
Vol 11 (12) ◽  
pp. e053028
Author(s):  
Liqaa Raffee ◽  
Hamza M Daradkeh ◽  
Khaled Alawneh ◽  
Aida I Al-Fwadleh ◽  
Moath Darweesh ◽  
...  

ObjectivesTo describe the effect of the COVID-19 lockdown in Jordan (21 March 2020–21 May 2020) on the incidence and patterns of toxic exposures and poisoning as compared with the same period from the previous year (21 March 2019–21 May 2019).DesignA retrospective descriptive study.MethodsCall data sourced from Pharmacy One Poison Center from the lockdown period (21 March 2020–21 May 2020) and the same period during 2019 (21 March 2019–21 May 2019) were revised. In addition, a database was established and analysed.ResultsWe noticed that not only did calls increased, but there was also a noticeable change in call patterns. Calls increased by 91% (544 vs 285 calls) during the lockdown period. Drugs were the most common among types of exposure, and the most prevalent route of exposure was ingestion. There was a notable increase in ocular exposure by 550% (13 vs 2 cases). The majority of exposures were at home and there were no occupational exposures. We found an increase in household cleaner exposure among males and an increase in alcohol exposure in females. Children aged below 5 years are the most affected. Even though there is an increase in the total number of cases, severe cases decreased.ConclusionThe lockdown effect on rates of toxic exposures was prominent, whether through the increase in calls or the change in patterns. As people spent more time at home, their exposure to toxic agents increased. Furthermore, cleaning recommendations led to the misuse of cleaning and disinfectant products, increasing exposures related to abating the COVID-19 infection.


2010 ◽  
Vol 113-116 ◽  
pp. 1342-1344 ◽  
Author(s):  
B. Gao ◽  
Y. Lin

In order to treat acid mine drainage with low-level uranium(AMDU), this paper considers 721 mine, located in Jiangxi province, as an example. So the permeable reactive barriers(PRBs) was been experimented as a new method for treatment AMDU. The results showed that the effects of removal of uranium are obvious and can meet radioactive wastewater discharged standard, and acidity meets guide standard. Moreover, the rock-water interaction mechanism between uranium and media of PRBs has been studied.


1978 ◽  
Vol 26 (11) ◽  
pp. 14-18
Author(s):  
Bertha A. Hohman ◽  
Marshal S. Levine

The role of nursing personnel in the medical monitoring of occupational exposures to the fire atmosphere is presented. The rationale and the techniques of the investigation and its impact on prevention are discussed.


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