Polycystic ovarian syndrome (PCOS) patients have a favorable response to ganirelix acetate during controlled ovarian hyperstimulation (COH) for in vitro fertilization (IVF)-embryo transfer (ET)

2002 ◽  
Vol 78 ◽  
pp. S149-S150 ◽  
Author(s):  
Nabal Bracero ◽  
Marcus Jurema ◽  
Nikos Vlahos ◽  
Lisa Kolp ◽  
Jairo Garcia
Keyword(s):  
In Vitro Fertilization ◽  
Embryo Transfer ◽  
Polycystic Ovarian Syndrome ◽  
Controlled Ovarian Hyperstimulation ◽  
Ovarian Hyperstimulation ◽  
Vitro Fertilization ◽  
Ovarian Syndrome

scholarly journals Changes in Coagulation and Fibrinolytic Indices in Women with Polycystic Ovarian Syndrome Undergoing Controlled Ovarian Hyperstimulation

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Ying Huang ◽  
Yong Zhao ◽  
Ling Yan ◽  
Yun-Hai Chuai ◽  
Ling-Ling Liu ◽  
...  
Keyword(s):  
Polycystic Ovarian Syndrome ◽  
Controlled Ovarian Hyperstimulation ◽  
Endocrine Function ◽  
Control Group ◽  
Ovarian Hyperstimulation ◽  
Vitro Fertilization ◽  
The Status ◽  
Pcos Group ◽  
Ovarian Syndrome

Background. Polycystic ovarian syndrome (PCOS) women undergoing in vitro fertilization and embryo transfer (IVF-ET) treatment always attain a low cumulative pregnancy rate disaccording with the satisfactory number of oocytes.Objective. We aim to evaluate the status of coagulation and fibrinolytic system in PCOS patients undergoing controlled ovarian hyperstimulation (COH) process.Method. Of the 97 women, 30 patients with PCOS composed the study group; 67 women of child-bearing age with normal endocrine function composed the control group. All participants underwent GnRH agonist standard long protocol, and plasma HCY, FVIII, FX, and D-dimer levels as well as hormone parameters were measured at day of full downregulation, hCG priming, and embryos transfer.Results. On day of full downregulation, FX levels were significantly higher in PCOS group (P<0.01). On hCG priming day, FX and estrogen levels in PCOS group were higher than in the control group and FVIII levels were significantly lower on day of embryos transfer whereas FX and E2 levels were significantly higher in PCOS group.Conclusion. Hypercoagulable state during peri-implantation phase would probably lead to poor microcirculation of endometrium and be one of the most important disadvantages of successful implantation and subsequent clinical pregnancy.

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