Elevated prolactin levels in oral contraceptive pill-related hypertension**Supported by grants from the Foundation of Gynecological Research, Finland, the Finnish Cultural Foundation (P. L. and T. R.), the Research Council for Medical Sciences, Academy of Finland, and the Medical Research Council of England (M. S.).

1981 ◽  
Vol 35 (4) ◽  
pp. 403-405 ◽  
Author(s):  
Pentti Lehtovirta ◽  
Tapio Ranta ◽  
Markku Seppälä
Keyword(s):  
Oral Contraceptive ◽  
Medical Research ◽  
Research Council ◽  
Medical Research Council ◽  
Oral Contraceptive Pill ◽  
Medical Sciences ◽  
Contraceptive Pill

scholarly journals The Use of Non-Human Primates in Biological and Medical Research: Evidence Submitted by FRAME to the Academy of Medical Sciences/Medical Research Council/Royal Society/Wellcome Trust Working Group

2005 ◽  
Vol 33 (5) ◽  
pp. 519-527 ◽  
Author(s):  
Nirmala Bhogal ◽  
Michelle Hudson ◽  
Michael Balls ◽  
Robert D. Combes
Keyword(s):  
Medical Research ◽  
Working Group ◽  
Royal Society ◽  
Research Council ◽  
Medical Research Council ◽  
Primate Research ◽  
Medical Sciences ◽  
Scientific Experts ◽  
Overwhelming Evidence ◽  
Fundamental Research

The Academy of Medical Sciences, the Medical Research Council, the Royal Society and the Wellcome Trust are undertaking a study into the use of non-human primates in biological and medical research. An independent working group of scientific experts, led by Sir David Weatherall, aims to produce a report summarising the findings of this study, early in 2006. The trends in primate research, and the nature and effects of recent and proposed changes in the global use of non-human primates in research, will be investigated. The associated ethical, welfare and regulatory issues, and the role and impact of the Three Rs principles of refinement, reduction and replacement will also be reviewed. As part of this study, a call for evidence was made. The evidence submitted by FRAME emphasised that the use of non-human primates for fundamental research or for regulatory testing still fails to take into account the fact that, although non-human primates are anatomically and physiologically similar to humans, they are not necessarily relevant models for studies on human disease or human physiology. FRAME continues to believe that we have a duty to ensure that these animals are not used without overwhelming evidence that they are the only suitable and relevant models for use in work of undeniable significance.

Correlação entre a frequência respiratória e escalas de avaliação de dispneia

2016 ◽  
Vol 13 (6) ◽  
Author(s):  
Ivete Alonso Bredda Saad ◽  
Mariana De Moraes ◽  
Vinicius Minatel ◽  
Bruna Alonso Saad
Keyword(s):  
Medical Research ◽  
Research Council ◽  
Medical Research Council

A avaliação da dispneia tem sido feita por meio de instrumentos como escala de Borg modificada, a escala de cores e a escala do Medical Research Council modificada (mMRC). O objetivo deste estudo foi correlacionar a frequência respiratória com a sensação de dispneia, através das escalas citadas, correlacioná-las entre si e verificar se o grau de alfabetização influenciou na resposta do paciente sobre a sensação de dispneia. Para avaliar o esforço físico utilizou-se o teste de caminhada de seis minutos. Este foi um estudo prospectivo, transversal e analítico-descritivo composto por 124 voluntários com diagnóstico de doença pulmonar. Para comparar as variáveis categóricas entre os grupos foram utilizados os testes Qui-Quadrado e exato de Fisher. Para comparar as variáveis contínuas foi utilizado o teste Kruskal-Wallis e para análise de correlação foi utilizado o coeficiente de correlação de Spearman. A idade média foi de 55,9 (± 13,08 anos), 14% eram analfabetos. Nos tempos de análise houve correlação positiva entre as escalas mMRC e Borg, r = 0,43, r = 0,61 e r = 0,55. Entre as escalas mMRC e Cores, observou-se correlação negativa. Concluiu-se que a frequência respiratória correlacionou-se com as três escalas. O grau de alfabetização não modificou a resposta do paciente em relação à sensação de dispneia.Palavras-chave: dispneia, fisioterapia, avaliação.

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