The Academy of Medical Sciences, Association of Medical Research Charities, Cancer Research UK, Biotechnology and Biological Sciences Research Council, Medical Research Council, Progress Educational Trust, Wellcome Trust, Wellcome Trust Sanger Institute (UK) Genome Editing in Human Cells – Initial Joint Statement

2017 ◽  
Vol 21 (1) ◽  
2005 ◽  
Vol 33 (5) ◽  
pp. 519-527 ◽  
Author(s):  
Nirmala Bhogal ◽  
Michelle Hudson ◽  
Michael Balls ◽  
Robert D. Combes

The Academy of Medical Sciences, the Medical Research Council, the Royal Society and the Wellcome Trust are undertaking a study into the use of non-human primates in biological and medical research. An independent working group of scientific experts, led by Sir David Weatherall, aims to produce a report summarising the findings of this study, early in 2006. The trends in primate research, and the nature and effects of recent and proposed changes in the global use of non-human primates in research, will be investigated. The associated ethical, welfare and regulatory issues, and the role and impact of the Three Rs principles of refinement, reduction and replacement will also be reviewed. As part of this study, a call for evidence was made. The evidence submitted by FRAME emphasised that the use of non-human primates for fundamental research or for regulatory testing still fails to take into account the fact that, although non-human primates are anatomically and physiologically similar to humans, they are not necessarily relevant models for studies on human disease or human physiology. FRAME continues to believe that we have a duty to ensure that these animals are not used without overwhelming evidence that they are the only suitable and relevant models for use in work of undeniable significance.


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