Su1469 Subclinical Abnormal Glucose Tolerance Is Associated With Reduced Survival of Patients With Compensated Cirrhosis and Normal Fasting Plasma Glucose. A Prospective Study

2014 ◽  
Vol 146 (5) ◽  
pp. S-477
Author(s):  
Diego Garcia-Compean ◽  
Joel O. Jaquez-Quintana ◽  
Fernando J. Lavalle-Gonzalez ◽  
Jose A Gonzalez ◽  
Linda E. Munoz-Espinosa ◽  
...  
2011 ◽  
Vol 86 (11) ◽  
pp. 1042-1049 ◽  
Author(s):  
Xuemei Sui ◽  
Carl J. Lavie ◽  
Steven P. Hooker ◽  
Duck-Chul Lee ◽  
Natalie Colabianchi ◽  
...  

Diabetes ◽  
1980 ◽  
Vol 29 (4) ◽  
pp. 272-277 ◽  
Author(s):  
G. Bolli ◽  
P. Compagnucci ◽  
M. G. Cartechini ◽  
F. Santeusanio ◽  
C. Cirotto ◽  
...  

Diabetes ◽  
1980 ◽  
Vol 29 (4) ◽  
pp. 272-277 ◽  
Author(s):  
G. Bolli ◽  
P. Compagnucci ◽  
M. G. Cartechini ◽  
F. Santeusanio ◽  
C. Cirotto ◽  
...  

Author(s):  
Tarekegn Geberhiwot ◽  
Angela Haddon ◽  
Mourad Labib

Background: Although the oral glucose tolerance test (OGTT) is the 'gold standard' for diagnosing prediabetes/diabetes, it is inconvenient for the patient and time consuming. The only alternative simple screening test is fasting plasma glucose (FPG). FPG concentrations of >6.0 mmol/L represent prediabetes/diabetes. FPG concentrations of 6.0 mmol/L may be considered 'normal', although some such patients will demonstrate abnormal glucose tolerance when subjected to an OGTT. We have evaluated the use of glycated haemoglobin (HbA1c) as a screening test for diabetes or impaired glucose tolerance (IGT) in patients who have risk factors for diabetes but FPG ≤6.0 mmol/L. Methods and results: A total of 580 patients with at least two risk factors for diabetes underwent an OGTT and HbA1c measurement. In all, 225 patients had a FPG ≤6.0 mmol/L and met the inclusion criteria. Of these, 23.1% ( n=52) had an abnormal OGTT result (45 had IGT and 7 had diabetes). Subjects with abnormal glucose tolerance had a higher percentage of HbA1c than subjects with normal glucose tolerance ( P<0.001). An HbA1c of 5.6% gave an optimal sensitivity of 72% and specificity of 77% to predict a 2 h plasma glucose ≥7.8 mmol/L. Conclusion: The use of FPG concentration followed by selective measurement of HbA1c in patients who are at high risk of developing diabetes may represent a reasonable approach to identifying patients requiring an OGTT.


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