scholarly journals Sa1017 Effects of Hyperbaric Oxygen Therapy on the Liver After Induction of the Hepatic Ischemia/Reperfusion Complex

2014 ◽  
Vol 146 (5) ◽  
pp. S-938
Author(s):  
Nathalia M. Cardoso ◽  
Daniela Antoniali ◽  
Ricardo Nejo Júnior ◽  
Leticia B. Baldim ◽  
Marina R. Silveira ◽  
...  
2014 ◽  
Vol 29 (suppl 1) ◽  
pp. 29-33 ◽  
Author(s):  
Marina Rodrigues Garcia da Silveira ◽  
Maria Rita Margarido ◽  
José Carlos Vanni ◽  
Ricardo Nejo Junior ◽  
Orlando de Castro-e-Silva

2014 ◽  
Vol 29 (suppl 2) ◽  
pp. 61-66 ◽  
Author(s):  
Daniele Moraes Losada ◽  
Agnaldo Bruno Chies ◽  
Omar Feres ◽  
Eleazar Chaib ◽  
Luiz Augusto Carneiro D'Albuquerque ◽  
...  

2007 ◽  
Vol 73 (3) ◽  
pp. 261-266
Author(s):  
Dennis E. Weiland

Fasciotomies performed for compartment syndrome and ischemic vascular disease often requires closure in 2 to 4 weeks by skin graft. This leaves the patient with an unsightly scar and a limb with reduced strength. The use of vacuum-assisted closure (VAC) and hyperbaric oxygen therapy (HBOT) quickly reduce the edema and permit earlier closure with adjacent skin. A study of three trauma patients with compartment syndrome, fasciotomies, and the use of the VAC and HBOT to close the fasciotomy wounds with adjacent skin is presented. The pathophysiology of compartment syndrome and ischemia-reperfusion syndrome is discussed. These patients had closure of the fasciotomy wounds in 3 to 18 days. The simultaneous use of HBOT and VAC accelerates the reduction of edema in a synergistic fashion, permitting early closure of fasciotomy wounds.


2011 ◽  
Vol 26 (6) ◽  
pp. 463-469 ◽  
Author(s):  
Rosemary Aparecida Furlan Daniel ◽  
Vinícius Kannen Cardoso ◽  
Emanuel Góis Jr ◽  
Rogério Serafim Parra ◽  
Sérgio Britto Garcia ◽  
...  

PURPOSE: Adequate tissue oxygenation is essential for healing. Hyperbaric oxygen therapy (HBOT) has potential clinical applications to treat ischemic pathologies, however the exact nature of any protective effects are unclear at present. We therefore investigated the potential role of HBOT in modulating the ischemia/reperfusion (I/R) injury response in intestinal model of I/R injury. METHODS: Male Wistar rats were subjected to surgery for the induction of intestinal ischemia followed by reperfusion. HBOT was provided before and/or after intestinal ischemia. Cell viability in the intestinal tissue was assessed using the MTT assay and by measuring serum malondealdehyde (MDA). Microvascular density and apoptosis were evaluated by immunohistochemistry. RESULTS: The results indicate that HBOT treatment pre- and post-ischemia reduces lesion size to the intestinal tissue. This treatment increases cell viability and reduces the activation of caspase-3, which is associated with increased number of tissue CD34 cells and enhanced VEGF expression. CONCLUSION: The hyperbaric oxygen therapy can limit tissue damage due to ischemia/reperfusion injury, by inducing reparative signaling pathways.


2012 ◽  
Vol 44 (8) ◽  
pp. 2333-2336 ◽  
Author(s):  
R.J. Ramalho ◽  
P.S.T. de Oliveira ◽  
R.C. Cavaglieri ◽  
C. Silva ◽  
P.R.B. Medeiros ◽  
...  

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