Long-Chain 3-Isopropyl Alkanes: A New Class of Sedimentary Acyclic Hydrocarbons

1998 ◽  
Vol 62 (6) ◽  
pp. 961-964 ◽  
Author(s):  
Stefan Schouten ◽  
Marianne Baas ◽  
Heidy M.E van Kaam-Peters ◽  
Jaap S Sinninghe Damsté
Keyword(s):  
New Class ◽  
Long Chain ◽  
Acyclic Hydrocarbons

Long-chain metabolites of α-tocopherol emerge from the shadow of their precursors: Α-13’-OH and Α-13’-COOH as a new class of regulatory metabolites

2016 ◽  
Vol 252 ◽  
pp. e209
Author(s):  
L. Schmölz ◽  
M. Wallert ◽  
S. Ciffolilli ◽  
S. Kluge ◽  
G. Cruciani ◽  
...  
Keyword(s):  
New Class ◽  
Long Chain

ChemInform Abstract: Long-Chain Acetals Derived from Sucrose as a New Class of Surfactants.

ChemInform ◽  
2010 ◽  
Vol 28 (29) ◽  
pp. no-no
Author(s):  
E. FANTON ◽  
C. FAYET ◽  
J. GELAS
Keyword(s):  
New Class ◽  
Long Chain

Recent Advances in the Total Synthesis of Clavaminols

Synthesis ◽  
2018 ◽  
Vol 50 (23) ◽  
pp. 4569-4576
Author(s):  
Tian Jin ◽  
Lu Zhao ◽  
Zhe-Bin Zheng ◽  
Xiao Liu ◽  
Liang Sun ◽  
...  
Keyword(s):  
Total Synthesis ◽  
Research Groups ◽  
Total Syntheses ◽  
New Class ◽  
Recent Advances ◽  
Molecular Architectures ◽  
Synthetic Approaches ◽  
Long Chain

Clavaminols are a new class of long-chain 2-amino-3-­alkanols that mostly contain 2R,3S-configurations. Owing to their interesting molecular architectures and promising activities, they have ­become popular targets for synthetic organic chemists. In this review, we highlight 12 total syntheses of clavaminols from different research groups during the period 2009 to 2018.1 Introduction2 Synthetic Approaches toward Clavaminols2.1 Total Synthesis by Chemla and Colleagues (2009)2.2 Total Synthesis by Greck and Colleagues (2010)2.3 Total Synthesis by Sutherland and Zaed (2011)2.4 Total Synthesis by Huang and Colleagues (2011)2.5 Total Synthesis by Kotora and Colleagues (2012)2.6 Total Synthesis by Kumar and Colleagues (2013)2.7 Total Synthesis by Prabhavathi Devi and Colleagues (2013 and 2016)2.8 Total Synthesis by Sarabia and Colleagues (2014)2.9 Total Synthesis by Mohapatra and Colleagues (2016)2.10 Total Synthesis by Lu and Colleagues (2016)2.11 Total Synthesis by Jin and Colleagues (2017)2.12 Total Synthesis by Kumar Pandey and Colleagues (2018)3 Conclusion

Long-Chain Diols: A New Class of Membrane Lipids from a Thermophilic Bacterium

Science ◽  
1986 ◽  
Vol 231 (4742) ◽  
pp. 1134-1136 ◽  
Author(s):  
J. L. POND ◽  
T. A. LANGWORTHY ◽  
G. HOLZER
Keyword(s):  
Membrane Lipids ◽  
Thermophilic Bacterium ◽  
New Class ◽  
Long Chain

New class of cocogem surfactants based on hexamethylenediamine, propylene oxide, and long chain carboxylic acids: Theory and application

2020 ◽  
Vol 86 ◽  
pp. 123-135 ◽  
Author(s):  
Elgun E. Hasanov ◽  
Ravan A. Rahimov ◽  
Yusif Abdullayev ◽  
Ziyafaddin H. Asadov ◽  
Gulnara A. Ahmadova ◽  
...  
Keyword(s):  
Carboxylic Acids ◽  
Propylene Oxide ◽  
New Class ◽  
Long Chain

Long chain arginine esters: A new class of cationic detergents for preparation of hydrophobic ion-paired complexes

2000 ◽  
Vol 78 (1) ◽  
pp. 59-65 ◽  
Author(s):  
David J Claffey ◽  
Jeffrey D Meyer ◽  
Robert Beauvais ◽  
Tessa Brandt ◽  
Eli Shefter ◽  
...  
Keyword(s):  
Tetradecyltrimethylammonium Bromide ◽  
New Class ◽  
Dna And Rna ◽  
Naturally Occurring ◽  
Cationic Detergents ◽  
Acidic Compounds ◽  
Oppositely Charged ◽  
Modest Level ◽  
Long Chain

The ability of stoichiometric amounts (based on charged groups) of ionic detergents to bind to oppositely charged ionic compounds has been recently reviewed. These hydrophobic ion-paired (HIP) complexes display altered solubility properties. Most of the work to date on HIP compelxes has focused on basic drugs and anionic detergents. It would be extremely useful to extend this approach to acidic compounds, including DNA and RNA. However, most cationic detergents are relatively toxic. It is hypothesized that detergents constructed from naturally occurring or well tolerated components, coupled by labile linkages, will be less toxic and still able to form strong HIP complexes. This study describes the synthesis and characterization of long chain alkyl esters of arginine. This class of cationic detergents, which have not been reported previously, are less cytotoxic than alkyltrimethylammonium detergents, possibly making them more acceptable in drug delivery applications. These arginine esters exhibit detergent-like properties. For example, the dodecyl ester of arginine has a critical micelle concentration of 0.07 mM, while being approximately 5-10 fold less toxic than tetradecyltrimethylammonium bromide. The arginine dodecyl ester forms stable HIP complexes with plasmid DNA. The complex is sufficiently stable to allow some modest level of transfection with Cos-7 cells in a time- and concentration-dependent fashion. This work demonstrates that arginine-based cationic detergents are effective ion-pairing agents, appear to be less toxic than alkyltrimethylammonium compounds, and form stable complexes with DNA.

scholarly journals Synthesis and Characterization of New Ethylenediamine Platinum(IV) Complexes Containing Lipophilic Carboxylate Ligands

1995 ◽  
Vol 2 (1) ◽  
pp. 57-63 ◽  
Author(s):  
M. Galanski ◽  
B. K. Keppler
Keyword(s):  
Axial Position ◽  
Synthesis And Characterization ◽  
Equatorial Position ◽  
Spectroscopic Techniques ◽  
Acyl Halide ◽  
Carboxylate Ligands ◽  
New Class ◽  
Carboxylate Groups ◽  
Long Chain

A series of new ethylenediamine (en) platinum(IV) complexes of the type Pt(IV)enX2A2 , with X2 = cyclobutane-1,1-dicarboxylato (CBDCA), dichloro or bis(decanoato) and A = acetato, dodecanoato, tetradecanoato, hexadecanoato, octadecanoato, adamantanecarboxylato (Ad) or 3α, 12α -diformoxy-5β-cholato (DFCA) were synthesized and characterized by elemental analysis, infrared and NMR (H1 and C13) spectroscopic techniques. Previous platinum(IV) compounds were usually restricted to trans-dihydroxo or trans-dichloro platinum(IV) complexes. Recently trans-dicarboxylato platinum(IV) complexes with mainly acetate, trifluoracetate or short-chain carboxylate groups (<11 carbons) in the axial position have been described in the literature[1,2,3]. In this paper we report on the synthesis and characterization of a new class of ethylenediamine platinum(IV) compounds that have high lipophilic long-chain carboxylate ligands either in the axial or equatorial position. The platinum(IV) compounds with the lipophilic trans-carboxylate ligands in the axial position were prepared by acylation of the trans-dihydroxo platinum(IV) species using an acyl halide in the presence of pyridine. In contrast to previous publications[1] the yields were excellent (up to 94%!).

Long-chain acetals derived from sucrose as a new class of surfactants

1997 ◽  
Vol 298 (1-2) ◽  
pp. 85-92 ◽  
Author(s):  
Elisabeth Fanton ◽  
Catherine Fayet ◽  
Jacques Gelas
Keyword(s):  
New Class ◽  
Long Chain
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