scholarly journals A role of cholinergic neurons on the 2-deoxyglucose uptake in hippocampus and cerebral cortex in young and old rat brain slices

1990 ◽  
Vol 52 ◽  
pp. 356
Author(s):  
Kohtaro Kodama ◽  
Shigenobu Shibata ◽  
Showa Ueki
1980 ◽  
Vol 190 (2) ◽  
pp. 333-339 ◽  
Author(s):  
M C W Minchin

1. Protoveratrine A increased the release of gamma-amino[3H]butyrate from small slices of rat cerebral cortex. This effect increased with increasing protoveratrine concentration, reaching a maximum at 100 microM. 2. Removal of Ca2+ from the superfusing medium did not change the increase in release due to 10 microM-protoveratrine; however, the Ca2+ antagonists, compound D-600, La3+, Mn2+, Mg2+ and also high Ca2+ concentration inhibited the effect of the alkaloid, as did procaine. 3. Protoveratrine A increased the uptake of 22Na+ into the slices with a similar dose-response curve to that found for gamma-aminobutyrate release. For the most part, the substances that inhibited protoveratrine-stimulated gamma-aminobutyrate release also inhibited 22Na+ uptake, although the correlation was not perfect. 4. Although extracellular Ca2+ is not required for protoveratrine-induced gamma-aminobutyrate release, an increase in Na+ influx that is susceptible to inhibition by some Ca2+ antagonists does appear to be associated with this phenomenon. However, the possibility remains that changes in the free intracellular Ca2+ concentration may be important for transmitter release induced by depolarizing veratrum alkaloids.


1991 ◽  
Vol 204 (3) ◽  
pp. 257-263 ◽  
Author(s):  
Matsuda Toshio ◽  
Shimizu Isao ◽  
Baba Akemichi

1999 ◽  
Vol 837 (1-2) ◽  
pp. 229-235 ◽  
Author(s):  
A.R Jayakumar ◽  
R Sujatha ◽  
V Paul ◽  
C Asokan ◽  
S Govindasamy ◽  
...  

2003 ◽  
Vol 552 (1) ◽  
pp. 135-148 ◽  
Author(s):  
Makoto Funahashi ◽  
Yoshihiro Mitoh ◽  
Atsushi Kohjitani ◽  
Ryuji Matsuo

2013 ◽  
Vol 24 (12) ◽  
pp. 2152-2157 ◽  
Author(s):  
Susana Cabrerizo ◽  
José Pedro De La Cruz ◽  
Juan Antonio López-Villodres ◽  
Javier Muñoz-Marín ◽  
Ana Guerrero ◽  
...  

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