scholarly journals A unique gene organization for two cholinergic markers, choline acetyltransferase and a putative vesicular transporter of acetylcholine.

1994 ◽  
Vol 269 (35) ◽  
pp. 21944-21947
Author(s):  
S. Bejanin ◽  
R. Cervini ◽  
J. Mallet ◽  
S. Berrard
Keyword(s):  
Choline Acetyltransferase ◽  
Gene Organization ◽  
Unique Gene ◽  
Vesicular Transporter ◽  
Cholinergic Markers

Choline acetyltransferase and the vesicular transporter of acetylcholine: A unique gene organization

1994 ◽  
Vol 88 (6) ◽  
pp. 367 ◽  
Author(s):  
Riccardo Cervini ◽  
Stéphane Bejanin ◽  
Jacques Mallet ◽  
Sylvie Berrard
Keyword(s):  
Choline Acetyltransferase ◽  
Gene Organization ◽  
Unique Gene ◽  
Vesicular Transporter

Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae

1995 ◽  
Vol 16 (5) ◽  
pp. 921-929 ◽  
Author(s):  
Brigitte Wieles ◽  
Dick Soolingen ◽  
Arne Holmgren ◽  
Rienk Offringa ◽  
Tom Ottenhoff ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Mycobacterium Leprae ◽  
Gene Organization ◽  
Unique Gene

scholarly journals Acetylcholine Levels and Choline Acetyltransferase Activity in Rat Cerebrovascular Bed after Uni- or Bilateral Sphenopalatine Ganglionectomy

1991 ◽  
Vol 11 (2) ◽  
pp. 253-260 ◽  
Author(s):  
François Dauphin ◽  
Jean W. Richard ◽  
Jacques Seylaz ◽  
Rémi Quirion ◽  
Edith Hamel
Keyword(s):  
Choline Acetyltransferase ◽  
Cerebral Arteries ◽  
Peripheral Arteries ◽  
Sphenopalatine Ganglion ◽  
Surgical Ablation ◽  
Chat Activity ◽  
Pial Vessels ◽  
Putative Origin ◽  
Cholinergic Markers ◽  
Choline Acetyltransferase Activity

Endogenous acetylcholine (ACh) levels and choline acetyltransferase (ChAT) activity were measured in several vascular segments (major cerebral arteries, cortical pial vessels, and peripheral arteries) and nervous tissues [including the sphenopalatine ganglion (SPG)] in the rat. The effects of uni- or bilateral surgical ablation of the SPG, a putative origin of the cholinergic cerebrovascular innervation, were investigated on these two specific cholinergic markers at various postoperative times. ChAT activity and ACh levels were enriched in the cerebral as compared to the peripheral arteries. Among the cerebrovascular tissues tested, ACh levels were particularly high in the circle of Willis and the vertebrobasilar segments and, to a lesser extent, in the middle cerebral artery. Lower levels were found in the small pial vessels and choroid plexus. Overall, ChAT activity measured in different arterial beds paralleled the distribution of ACh. Following uni- or bilateral removal of the SPG, slight reductions (18–36%, statistically not significant) were observed in ChAT activity in rostral cerebral arteries and pial vessels overlying the frontal cortex. Similarly, bilateral ganglionectomy resulted in minor decreases (11–22%, not significant) in the cerebrovascular contents of ACh in these same vascular segments. These results clearly show that the SPG does not or only partly contributes to the cholinergic fibers that supply the cerebrovascular bed.

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