Choline acetyltransferase and the vesicular transporter of acetylcholine: A unique gene organization

1994 ◽  
Vol 88 (6) ◽  
pp. 367 ◽  
Author(s):  
Riccardo Cervini ◽  
Stéphane Bejanin ◽  
Jacques Mallet ◽  
Sylvie Berrard
Keyword(s):  
Choline Acetyltransferase ◽  
Gene Organization ◽  
Unique Gene ◽  
Vesicular Transporter

Unique gene organization of thioredoxin and thioredoxin reductase in Mycobacterium leprae

1995 ◽  
Vol 16 (5) ◽  
pp. 921-929 ◽  
Author(s):  
Brigitte Wieles ◽  
Dick Soolingen ◽  
Arne Holmgren ◽  
Rienk Offringa ◽  
Tom Ottenhoff ◽  
...  
Keyword(s):  
Thioredoxin Reductase ◽  
Mycobacterium Leprae ◽  
Gene Organization ◽  
Unique Gene

Unique gene organization: alternative splicing in Drosophila produces two structurally unrelated proteins

Gene ◽  
1997 ◽  
Vol 198 (1-2) ◽  
pp. 229-236 ◽  
Author(s):  
Randy C. Mottus ◽  
Ian P. Whitehead ◽  
Michael O'Grady ◽  
Richard E. Sobel ◽  
Rod H.L. Burr ◽  
...  
Keyword(s):  
Alternative Splicing ◽  
Gene Organization ◽  
Unique Gene

Ultrastructural Localization of Acetylcholinesterase in the Arcuate Nucleus and Median Eminence of the Rat

1977 ◽  
Vol 35 ◽  
pp. 440-441
Author(s):  
K.A. Carson ◽  
C.B. Nemeroff ◽  
M.S. Rone ◽  
J.S. Kizer ◽  
J.S. Hanker
Keyword(s):  
Choline Acetyltransferase ◽  
Median Eminence ◽  
Arcuate Nucleus ◽  
Cholinergic Neurons ◽  
Ultrastructural Localization ◽  
Male Rats ◽  
Neonatal Rats ◽  
Good Marker ◽  
Chemical Studies ◽  
High Doses

Biochemical, physiological, pharmacological, and more recently enzyme histo- chemical data have indicated that cholinergic circuits exist in the hypothalamus. Ultrastructural correlates of these pathways such as acetylcholinesterase (AchE) positive neurons in the arcuate nucleus (ARC) and stained terminals in the median eminence (ME) have yet to be described. Initial studies in our laboratories utilizing chemical lesioning and microdissection techniques coupled with microchemical and light microscopic enzyme histo- chemical studies suggested the existence of cholinergic neurons in the ARC which project to the ME (1). Furthermore, in adult male rats with Halasz deafferentations (hypothalamic islands composed primarily of the isolated ARC and the ME) choline acetyltransferase (ChAc) activity, a good marker for cholinergic neurons, was not significantly reduced in the ME and was only somewhat reduced in the ARC (2). Treatment of neonatal rats with high doses of monosodium 1-glutamate (MSG) results in a lesion largely restricted to the neurons of the ARC.

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