scholarly journals A SPECTROPHOTOMETRIC METHOD FOR THE MEASUREMENT OF RIBONUCLEASE ACTIVITY

1946 ◽  
Vol 164 (2) ◽  
pp. 563-568 ◽  
Author(s):  
M. Kunitz
Keyword(s):  
Spectrophotometric Method ◽  
Ribonuclease Activity

Spectrophotometric Method for Following Periodate Oxidations

1949 ◽  
Vol 21 (2) ◽  
pp. 315-315 ◽  
Author(s):  
N McDonald ◽  
Jacqueline Thompsett ◽  
J Mead
Keyword(s):  
Spectrophotometric Method

THE HORMONAL CONTROL OF RIBONUCLEASE ACTIVITY IN THE LYMPHATIC TISSUE OF MICE

1973 ◽  
Vol 74 (1) ◽  
pp. 201-208 ◽  
Author(s):  
D. Maor ◽  
E. Eylan ◽  
P. Alexander
Keyword(s):  
Growth Hormone ◽  
Lymph Nodes ◽  
Hormonal Control ◽  
Ribonuclease Activity ◽  
Lymphatic Tissue

ABSTRACT Ribonuclease activity in thymus and lymph nodes is stimulated by cortisone; insulin increases ribonuclease activity only in the thymus. Growth hormone and theophylline do not cause changes in thymus and lymph nodes ribonuclease levels. Injections of cortisone combined with growth hormone or with theophylline increase the activity more than cortisone alone. Insulin does not enhance the action of cortisone on ribonuclease activity. A synergistic loss in weight of thymus and spleen was found after administration of cortisone in combination with either growth hormone or with theophylline.

Novel UV Spectrophotometric Method for the Quantitative Analysis of CefpodoximeProxetil in Pharmaceutical Formulations by First Derivative Technique

2017 ◽  
Vol 8 (03) ◽  
Author(s):  
Potdar S. S. ◽  
Karajgi S. R. ◽  
Simpi C. C. ◽  
Kalyane N. V.
Keyword(s):  
Quantitative Analysis ◽  
Spectrophotometric Method ◽  
Dosage Form ◽  
Pharmaceutical Formulations ◽  
First Derivative ◽  
Good Linearity ◽  
Beer's Law ◽  
Beer’S Law ◽  
Tablet Dosage ◽  
Ich Guideline

The spectrophotometric method for estimation of CefpodoximeProxetil employed first derivative amplitude UV spectrophotometric method for analysis using methanol as solvent for the drug. CefpodoximeProxetil has absorbance maxima at 235nm and obeys Beer’s law in concentration range 10-50µg/ml with good linearity i.e. r2 about 0.999. The recovery studies established accuracy of the proposed method; result validated according to ICH guideline. Results were found satisfactory and reproducible. The method was successfully for evaluation of CefpodoximeProxetil in tablet dosage form without interference of common excipients.

Extractive Spectrophotometric Method for the Determination of Glibenclamide by Ion-Pair Complex in Pure Form and Pharmaceutical Formulation

2019 ◽  
Vol 9 (o3) ◽  
Author(s):  
RUAA MUAYAD MAHMOOD ◽  
HAMSA MUNAM YASSEN ◽  
SAMAR , NAJWA ISSAC ABDULLA AHMED DARWEESH ◽  
NAJWA ISSAC ABDULLA
Keyword(s):  
Spectrophotometric Method ◽  
Molar Absorptivity ◽  
Ion Pair ◽  
Pharmaceutical Formulation ◽  
Ratio Method ◽  
Colored Complex ◽  
Colored Product ◽  
Method Of Continuous Variation ◽  
Job's Method

Simple, rapid and sensitive extractive spectrophotometric method is presented for the determination of glibenclamide (Glb) based on the formation of ion-pair complex between the Glb and anionic dye, methyl orange (MO) at pH 4. The yellow colored complex formed was quantitatively extracted into dichloromethane and measured at 426 nm. The colored product obeyed Beer’s law in the concentration range of (0.5-40) μg.ml-1. The value of molar absorptivity obtained from Beer’s data was found to be 31122 L.mol-1.cm-1, Sandell’s sensitivity value was calculated to be 0.0159 μg.cm-2, while the limits of detection (LOD) and quantification (LOQ) were found to be 0.1086 and 0.3292 μg.ml-1, respectively. The stoichiometry of the complex created between the Glb and MO was 1:1 as determined via Job’s method of continuous variation and mole ratio method. The method was successfully applied for the analysis of pharmaceutical formulation.

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