scholarly journals INFLUENCE OF ANTERIOR PITUITARY SUBSTANCES ON THE TOTAL IODINE CONTENT OF THE THYROID GLAND IN THE YOUNG DUCK

1932 ◽  
Vol 95 (1) ◽  
pp. 89-94
Author(s):  
J.A. Schockaert ◽  
G.L. Foster
Keyword(s):  
Thyroid Gland ◽  
Anterior Pituitary ◽  
Iodine Content ◽  
Total Iodine

scholarly journals Iodine and iodothyronine content in human neonate thyroid gland

2002 ◽  
Vol 54 (3-4) ◽  
pp. 69-74 ◽  
Author(s):  
Svetlana Savin-Zegarac ◽  
Dubravka Cvejic ◽  
Olgica Nedic ◽  
R. Radosavljevic ◽  
Ivana Petrovic
Keyword(s):  
Thyroid Gland ◽  
Gestational Age ◽  
Thyroid Tissue ◽  
Iodine Content ◽  
Postnatal Life ◽  
Total Iodine ◽  
Mean Values ◽  
Human Neonate ◽  
The Mean ◽  
Human Neonates

A few years after the iodine content of salt in Serbia was increased from 7 to 15 mg/kg NaCI, iodine, thyroxine (T4) and triiodothyronine (T3) concentrations were measured in thyroid tissue obtained at autopsy from 21 human neonates who died within 30 days after birth. The thyroidal iodine as well as T4 and T3 content per gland in?creased progressively with gestational age of human neonates (r = 0.73, 0.70 and 0.67 respectively, p < 0.001). In seven newborns (gestational age 36 to 41 weeks) the mean values for total iodine, T4 and T3 per gland were 109.1 ?g, 52.2 ?g and 4.4 ?g respectively. The results of iodine and iodothyroninc content found in neonatal thyroid gland, particularly at the end of gestation and a few days of postnatal life, indicates that the iodine supply was satisfactory.

THE CONTENT OF THYROID HORMONES AND OTHER IODINATED COMPOUNDS IN THYROID TISSUE IN AUTOIMMUNE THYROIDITIS

1972 ◽  
Vol 69 (2) ◽  
pp. 309-320 ◽  
Author(s):  
B.-A. Lamberg ◽  
J. Mäenpää ◽  
V. Kivikangas ◽  
R. Karlsson ◽  
P. Saarinen
Keyword(s):  
Thyroid Gland ◽  
Autoimmune Thyroiditis ◽  
Thyroid Tissue ◽  
Iodine Content ◽  
Distribution Profile ◽  
Surgical Biopsy ◽  
Total Iodine ◽  
Hypothyroid Patients ◽  
Cellulose Column

ABSTRACT The total iodine content and the content of iodocompounds in the thyroid gland were studied in 9 patients with autoimmune thyroiditis. The thyroids were labelled in vivo with radioactive iodine before surgical biopsy. Five grams of tissue were homogenized and the iodocompounds were separated both by paper chromatography and on a cellulose column. The distribution profile of both the radioactive and the stable compounds was determined. The thyroid tissue contained on an average 11.0 ± 8.0 (sd) per cent of radioactive and 15.0 ± 9.4 per cent of stable iodothyronines. The MIT/DIT ratio was 1.16 ± 0.26 for the radioactive and 0.92 ± 0.30 for the stable compounds. Clinically evident hypothyroidism occurred only in patients with a very low iodine content and was not correlated with the proportion of iodothyronines found in the thyroid tissue. For instance, in two hypothyroid patients the iodothyronines corresponded to about 20 per cent of the iodocompounds of the tissue. These findings suggest that iodine depletion of the thyroid gland plays an important role in the development of clinical hypothyroidism in autoimmune thyroiditis and that up to a very late stage of the disease the thyroid is evidently capable of producing iodothyronines in fairly normal proportions.

Effect of Estrone on Some Criteria of Thyroid Function

1958 ◽  
Vol 193 (2) ◽  
pp. 408-410 ◽  
Author(s):  
Warner H. Florsheim
Keyword(s):  
Amino Acids ◽  
Amino Acid ◽  
Thyroid Gland ◽  
Thyroid Function ◽  
Iodine Content ◽  
Amino Acid Pattern ◽  
Acute Administration ◽  
Stock Diet ◽  
Total Iodine

The effects of estrogen upon thyroidal I131 uptake, hormone discharge, total iodine content and distribution of radioiodine among the iodinated amino acids of the thyroid gland have been investigated in orchiectomized rats. Acute administration of estrone increased significantly the 24-hour I131 uptake and augmented thyroidal weight at the higher of the two levels employed. It had no effect upon the serum PBI, the I127 content of the thyroid or the iodinated amino acid pattern. I131 discharge from the thyroid was slowed significantly by estrone, both on a stock diet and when propylthiouracil was used to block I131 reaccumulation.

TheIn VivoMeasurement of the Total Iodine Content of the Thyroid Gland by X-Ray Fluorescence

Radiology ◽  
1978 ◽  
Vol 126 (1) ◽  
pp. 197-200 ◽  
Author(s):  
Daniel A. Gollnick ◽  
Moses A. Greenfield
Keyword(s):  
Thyroid Gland ◽  
Iodine Content ◽  
Total Iodine ◽  
X Ray

DIE ZUSAMMENSETZUNG DER JODHALTIGEN VERBINDUNGEN UND IHRE BEZIEHUNG ZUM JODUMSATZ IN EUTHYREOTEN STRUMEN

1962 ◽  
Vol 41 (4) ◽  
pp. 584-594 ◽  
Author(s):  
Dankwart Reinwein ◽  
Erich Klein
Keyword(s):  
Column Chromatography ◽  
Iodine Content ◽  
High Plasma ◽  
Secretion Rate ◽  
Total Iodine ◽  
Iodine Compound ◽  
Hormonal Secretion ◽  
Carrier Free ◽  
Iodine Metabolism ◽  
Diffuse Goiter

ABSTRACT The iodine metabolism was investigated in 29 patients with euthyroid non-endemic diffuse goiter. 1 to 14 days before thyroidectomy the patients received carrier-free 131I. The chemical iodine fractions (PBI, BEI and iodide) of the thyroid and the labelled iodine compound were analyzed by means of paper- and column chromatography. In one gland the total iodine content varied only by ± 19.6% of the average, the relative shares of PBI, BEI and iodide as well as that of the iodoamino acids being equal. Monoiodotyrosine, diiodotyrosine and thyroxine were found in the thyroid homogenate without hydrolysis. The homogenate after hydrolysis contained more iodotyrosines at the expense of iodothyronines than do normal glands. 17 goiters with normal 131I-uptake showed a high total iodine content (14.2 ± 5.0 mg) whilst 9 goiters with an increased 131I-uptake had low values (3.58 ± 0.6 mg). The opposite was found for the relative shares of BEI with the chromatographically isolated iodothyronines thyroxine, triiodothyronine and an unidentified iodine compound. Goiters with »high plasma PB131I« were characterized by a faster transfer of 131I into the more heavily iodinated compounds than is found in glands with a normal hormonal secretion rate. The highest values for the iodothyronines were found in goiters with increased 131I-uptake together with a high hormonal secretion rate. From this study it appears that the changes in the iodine-poor glands are due to a defective exo- or endogenous iodine supply. The observed alterations in iodine-rich glands are probably induced by a faulty iodine utilization characterized by an incomplete iodotyrosyl-coupling defect.

PARTIAL FAILURE OF ANTERIOR PITUITARY AND THYROID PRESENTING AS MYXOEDEMA

1975 ◽  
Vol 79 (4) ◽  
pp. 688-690
Author(s):  
A. D. Toft ◽  
W. J. Irvine
Keyword(s):  
Thyroid Gland ◽  
Anterior Pituitary ◽  
Clinical Presentation ◽  
Present Report ◽  
Thyrotrophin Releasing Hormone ◽  
Releasing Hormone ◽  
Partial Failure ◽  
Impaired Function ◽  
Precise Evaluation ◽  
Thyroid Axis

ABSTRACT The development of a sensitive radioimmunoassay of plasma thyrotrophin (TSH) and the isolation and synthesis of thyrotrophin-releasing hormone (TRH) allows a precise evaluation of the disordered brain-thyroid axis. The present report describes a patient who presented with myxoedema due to partial failure of both the anterior pituitary and the thyroid gland. The degree of impaired function of either gland alone would not have caused her clinical presentation.

STUDIES OF IODINE METABOLISM IN ICELAND

1964 ◽  
Vol 46 (4) ◽  
pp. 679-683 ◽  
Author(s):  
W. D. Alexander ◽  
Th. Veiger Gudmundsson ◽  
M. M. Bluhm ◽  
R. McG. Harden
Keyword(s):  
Thyroid Gland ◽  
Iodine Content ◽  
Iodine Uptake ◽  
Hormone Production ◽  
High Iodine ◽  
Iodine Level ◽  
Iodine Metabolism ◽  
Inorganic Iodine

ABSTRACT The relation between plasma inorganic iodine level, thyroid clearance and absolute iodine uptake of the thyroid gland has been studied in Iceland and compared with results obtained in Glasgow using identical methods. In Iceland the plasma inorganic iodine (PII) is higher than in Glasgow due to the high iodine content of the diet and the thyroid clearance lower. This adjustment is, however, incomplete, relatively high PII levels being associated with a low thyroid clearance and a raised absolute uptake by the thyroid. There was no evidence of increased hormone production as reflected in the serum PBI.

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